Results 41 to 50 of about 74,859 (265)

Synthesis of purines and adenines containing the hexafluoroisopropyl group

Beilstein Journal of Organic Chemistry, 2020
Several new derivatives of adenine, purine, and theophylline containing the (CF3)2CH group connected to a nitrogen atom of the imidazole ring were prepared by the reaction of 2,2,4,4-tetrakis(trifluoromethyl)-1,3-dithietane (1) with the corresponding ...
Viacheslav Petrov, Rebecca J. Dooley, Alexander A. Marchione, Elizabeth L. Diaz, Brittany S. Clem, William Marshall   +5 more
doaj   +1 more source

Lipid profiling of polarized human monocyte-derived macrophages [PDF]

Prostaglandins & Other Lipid Mediators, 2016
The highly orchestrated transcriptional and metabolic reprogramming during activation drastically transforms the main functions and physiology of human macrophages across the polarization spectrum. Lipids, for example, can modify protein function by acting remotely as signaling molecules but also locally by altering the physical properties of cellular ...
J Rafael, Montenegro-Burke, Jessica A, Sutton, Lisa M, Rogers, Ginger L, Milne, John A, McLean, David M, Aronoff   +5 more
openaire   +2 more sources

Tetraoxanes as inhibitors of apicomplexan parasites Plasmodium falciparum and Toxoplasma gondii and anti-cancer molecules [PDF]

Journal of the Serbian Chemical Society, 2015
New cyclohexylidene 1,2,4,5-tetraoxanes with polar guanidine and urea based groups were synthesized and evaluated for antimalarial activity against chloroquine resistant and susceptible Plasmodium falciparum strains.
Opsenica Dejan M., Radivojević Jelena, Matić Ivana Z., Štajner Tijana, Knežević-Ušaj Slavica, Đurković-Đaković Olgica, Šolaja Bogdan A.   +6 more
doaj   +1 more source

Inequalities concerning polar derivative of polynomials

Annales UMCS, Mathematica, 2011
In this paper we obtain certain results for the polar derivative of a polynomial \(p(z) = c_nz^n +\sum_{j=\mu}^n c_{n-j}z^{n-j}\), \(1\leq\mu\leq n\), having all its zeros on \(|z| = k\), \(k\leq 1\), which generalizes the results due to Dewan and Mir, Dewan and Hans.
Ahuja, Arty, Dewan, K. K., Hans, Sunil
openaire   +2 more sources

Results of the Childhood Cancer and Leukaemia Group's United Kingdom Relapsed Wilms Tumour Trial

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background The United Kingdom relapsed Wilms tumour (UKW‐R) trial aimed to improve the historically low survival rates after relapse of Wilms tumour (WT) through a prospective national risk‐stratified protocol. The trial also evaluated efficacy and toxicity of high‐dose melphalan.
Sucheta J. Vaidya, Veronica Moroz, Juliet Hale, Vesna Pavasovic, Rachel Hobson, Patricia Sartori, Daniel Saunders, Mark Powis, Gordan M. Vujanic, Stephen Baker, Kathy Pritchard‐Jones   +10 more
wiley   +1 more source

Alveolar Soft Part Sarcoma in Pediatric and Young Adult Patients: A Report From the Children's Oncology Group Study ARST0332

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Alveolar soft part sarcoma (ASPS) is a rare soft tissue sarcoma occurring most commonly in adolescence and young adulthood. Methods We present the clinical characteristics, treatments, and outcomes of patients with newly diagnosed ASPS enrolled on the Children's Oncology Group study ARST0332.
Jacquelyn N. Crane, Wei Xue, Amira Qumseya, Thomas Scharschmidt, Kathryn R. Tringale, Oscar Lopez Nunez, Jiaqi Hu, Donald A. Barkauskas, Rajkumar Venkatramani, Sheri L. Spunt, Aaron R. Weiss, Noah C. Federman   +11 more
wiley   +1 more source

Refinements of inequalities on extremal problems of polynomials

Open Mathematics
Let H(z) be a polynomial of degree n, and for any complex number α, let D α H(z) = nH(z) + (α − z)H′(z) denote the polar derivative of H(z) with respect to α.
Devi Maisnam Triveni, Singh Thangjam Birkramjit, Chanam Barchand   +2 more
doaj   +1 more source

Polar compactons and solitons in a two dimensional optical waveguide: Theory and simulations

Results in Optics, 2023
The propagation of optical cylindrical compactons and solitons in a two dimensional nonlocal nonlinear waveguide is deeply investigated by carrying a particular emphasis on its nonlinear response function.
Fabien Kenmogne, Hatou-Yvelin Donkeng, Hervé Simo, Alexandre Mando Kongne, Joel Bruno Gonpe Tafo, Alexandre Teplaira Boum, David Yemélé   +6 more
doaj   +1 more source

Evaluation of the Utility of Baseline Echocardiogram in Patients With Standard Risk Precursor B‐Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
Abstract Background A routine baseline echocardiogram is often obtained prior to anthracycline administration in children with cancer. The utility of baseline echocardiogram is unclear in patients with standard risk B‐cell acute lymphoblastic leukemia (SR B‐ALL) as their anthracycline cumulative dose is low.
Ziyad Alrajhi, Alice Pozza, Luc Mertens, Adam Paul Yan, Sarah Alexander   +4 more
wiley   +1 more source

15 alpha-hydroxylation of a bile acid analogue, sodium 3 alpha,7 alpha-dihydroxy-25,26-bishomo-5 beta-cholane-26-sulfonate in the hamster.

Journal of Lipid Research, 1996
The metabolism of 3 alpha,7 alpha-dihydroxy-25,26-bishomo-5 beta-cholane-26-sulfonate (bishomoCDC-sul), the sulfonate analogue of bishomochenodeoxycholic acid, and its effect on biliary bile acid composition were studied during chronic administration in ...
T Mikami, A Ohshima, E H Mosbach, B I Cohen, N Ayyad, M Yoshii, K Ohtani, K Kihira, C D Schteingart, T Hoshita   +9 more
doaj   +1 more source