Results 71 to 80 of about 314,270 (307)

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Effects of Zn Doping on Optical Properties of Polycrystalline β-Ga₂O₃

Inorganics
In this study, Zn-doped Ga2O3 polycrystalline samples were prepared by solid-phase sintering, and the effects of Zn doping on the optical properties of Ga2O3 were investigated.
Yue Yan, Shuai Zhu, Jing Yang, Yuanyuan Zhang, Wei Bai, Xiaodong Tang   +5 more
doaj   +1 more source

Terrace scarp deflation as a renewable source for eolian sediments in an Arctic periglacial setting

, 1987
Glacial, glaciofluvial, and glaciolacustrine sediments deposited by the retreating Vibekes Glacier are being actively reworked into sand dunes and loess sheets on the tops of glaciofluvial terraces downvalley from Vibekes Glacier and Vihekes S ø ...
Swett, Keene, Mann, Keith
core   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Atomistic phase transition dynamics of In2Se3 semiconductor

Nano Research
van der Waals (vdW) layered α-In2Se3 possesses stable ferroelectricity even down to monolayer, showing great promise in emerging ferroelectric semiconductor non-volatile memory and in-memory computing.
Yufan Zheng, Beituo Liu, Fengrui Sui, Rui Ge, Yilun Yu, Rong Jin, Jiawen Dai, Shujing Jia, Fangyu Yue, Ruijuan Qi, Junhao Chu   +10 more
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Polar Materials Part 1: Classification and History

, 2008
In part I of this paper, an detailed classification of polar materials is presented. A historical background of the polar materials is outlined. Terminologies such as piezo-, pyro-, ferro-, paraeleclrics, etc., are defined.
Kamel, TM Talal, With, de, G., Kamel, T.M., With, de, G.; id_orcid, With, G Bert de   +4 more
core  

Enhancing ferroelectric photovoltaic effect by polar order engineering [PDF]

, 2018
Ferroelectric materials for photovoltaics have sparked great interest because of their switchable photoelectric responses and above-bandgap photovoltages that violate conventional photovoltaic theory.
Schmidt, D., Schmidt, Daniel, Tan, L.Z., Wang, Le, Rusydi, A., Wang, J., Zheng, Fan, Wang, L., Rusydi, Andrivo, Rappe, Andrew M, Chang, L., Chang, Lei, Rappe, Andrew M., You, Lu, Wang, Junling, Tan, Liang Z., Fang, L., You, L., Ma, Guohong, Rappe, A.M., Zhang, Z., Zhou, Yang, Zhang, Zeyu, Tan, Liang Z, Zhou, Y., Fang, Liang, Zheng, F., Ma, G.   +27 more
core   +1 more source

Hot-wall MOCVD of N-polar group-III nitride materials

, 2021
Group III-Nitride semiconductors: indium nitride (InN), gallium nitride (GaN), aluminum nitride (AlN) and their alloys continue to attract significant scientific interest due to their unique properties and diverse applications in photonic and electronic ...
Zhang, Hengfang, Hengfang Zhang
core   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source