Results 71 to 80 of about 380,733 (291)

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Modern methods for the determination of polar motion and UT1 [PDF]

, 1978
The applications and Doppler satellite observations, laser ranging to artificial satellites and the Moon, and astronomic radio interferometry to monitoring polar motion and Universal Time System 1 (UT1) are discussed.
Carter, W. S.
core   +1 more source

On 2D Viscoelasticity with Small Strain

, 2009
An exact two-dimensional rotation-strain model describing the motion of Hookean incompressible viscoelastic materials is constructed by the polar decomposition of the deformation tensor.
C. Liu, D. Christodoulou, F. John, F. John, F.H. Lin, F.H. Lin, J.Y. Chemin, K.O. Friedrichs, P.L. Lions, R. Agemi, S. Klainerman, S. Klainerman, T.C. Sideris, T.C. Sideris, T.C. Sideris, T.C. Sideris, Y. Chen, Z. Lei, Z. Lei, Z. Lei, Z. Lei, Zhen Lei   +21 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Reducing filter effects in GRACE-derived polar motion excitations

Earth, Planets and Space, 2019
Polar motion is caused by mass redistribution and motion within the Earth system. The GRACE (Gravity Recovery and Climate Experiment) satellite mission observed variations of the Earth’s gravity field which are caused by mass redistribution.
Franziska Göttl, Michael Murböck, Michael Schmidt, Florian Seitz   +3 more
doaj   +1 more source

Third order superintegrable systems separating in polar coordinates

, 2010
A complete classification is presented of quantum and classical superintegrable systems in $E_2$ that allow the separation of variables in polar coordinates and admit an additional integral of motion of order three in the momentum.
Cosgrove C M, Drach J, Frédérick Tremblay, Hietarinta J, Kalnins E G, Kalnins E G, Kalnins E G, Kalnins E G Miller W Pogosyan G S, Marquette I, Marquette I, Marquette I, Mitrinović D S, Pavel Winternitz, Quesne C, Tremblay F, Tremblay F, Tsiganov A V, Winternitz P, Winternitz P, Wojciechowski S   +19 more
core   +1 more source

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source

Polar electrostatic forces drive poleward chromosome motions [PDF]

Cell Division, 2014
Recent experiments revealing nanoscale electrostatic force generation at kinetochores for chromosome motions have prompted models for interactions between positively charged molecules in kinetochores and negative charge at and near the plus ends of microtubules.
Gagliardi, Lucian John, Shain, Daniel H
openaire   +2 more sources

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Modeling mobile robot motion with polar representations [PDF]

2009 IEEE/RSJ International Conference on Intelligent Robots and Systems, 2009
This article compares several parameterizations and motion models for improving the estimation of the nonlinear uncertainty distribution produced by robot motion. In previous work, we have shown that the use of a modified polar parameterization provides a way to represent nonlinear measurements distributions in the Cartesian space as linear ...
Djugash, Joseph A., Singh, Sanjiv, Grocholsky, Benjamin   +2 more
openaire   +1 more source