Results 61 to 70 of about 65,927 (307)

Christian Religious Education in Divided Societies: Resisting Polarisation and Reimagining Civic Engagement [PDF]

Pharos Journal of Theology
Contemporary societies are increasingly marked by political, cultural, and religious polarisation that undermines social cohesion and democratic life. This condition presents not only a political crisis but also a pedagogical and theological challenge ...
Daniel Sudibyo Tjandra
doaj   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Occupational Prestige and Gendered Polarisation [PDF]

Occupations are at the core of the restructuring of labour markets. It is occupations that, due to technologisation, stand the risk of being fundamentally changed or even eliminated. Occupations are the ‘backbone’ of social stratification.
Ulfsdotter Eriksson, Ylva,, Nordlander, Erica,   +1 more
core   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Social polarisation at the local level: a four-town comparative study on the challenges of politicising inequality in Britain [PDF]

, 2020
This paper examines how intensifying inequality in the UK plays out at a local level, in order to bring out the varied ways polarisation takes place ‘on the ground’.
Savage, Mike, Ebrey, J., Ebrey, Jill, Cant, S., Glucksberg, L., Savage, M., Koch, Insa, Fransham, Mark, Cant, Sarah, Glucksberg, Luna, Koch, I., Fransham, M.   +11 more
core   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

High performance optical fibre polarisers based on long period gratings in birefringent optical fibres [PDF]

, 1997
We have demonstrated the feasibility of achieving high performance fibre polarisers (insertion loss 30 dB), based on polarisation mode dispersion in a long period grating.
Ortega, B., Dong, L., de Sandro, J.P., Reekie, L., Laming, R.I., Liu, W.F.   +5 more
core   +1 more source

Monitoring and early warning detection of collapse and subsidence sinkholes using an optical fibre seismic sensor

Cogent Engineering
We present and experimentally demonstrate a seismic ambient noise monitoring optical fibre sensor for early warning detection of sinkholes. The developed optical fibre sensor is designed for warning alert of subsidence and cover collapse sinkholes.
James Jena, Gaathier Mahed, Tichakunda Chabata, Moctar Doucoure, Timothy Gibbon   +4 more
doaj   +1 more source

Quo Vadis, Business? The migration of companies between cities using the example of the Mazowieckie voivodship in Poland

Miscellanea Geographica: Regional Studies on Development, 2020
Relations between metropolitan core cities and regional and sub-regional centres are part of a broader discussion on the importance of metropolitan areas for the development of regions.
Cybulska Magdalena, Dziemianowicz Wojciech   +1 more
doaj   +1 more source