Results 101 to 110 of about 86,994 (300)

Antibodies to Enteroviruses in Cerebrospinal Fluid of Patients with Acute Flaccid Myelitis. [PDF]

, 2019
Acute flaccid myelitis (AFM) has caused motor paralysis in >560 children in the United States since 2014. The temporal association of enterovirus (EV) outbreaks with increases in AFM cases and reports of fever, respiratory, or gastrointestinal illness
Briese, Thomas, Burns, Jane C, Caciula, Adrian, Garcia, Joel A, Hetzler, Kimbell L, Jain, Komal, Konopka-Anstadt, Jennifer L, Lipkin, W Ian, Marine, Rachel L, Mishra, Nischay, Ng, James, Ng, Terry Fei Fan, Nix, W Allan, Oberste, M Steven, Price, Adam, Routh, Janell A, Thakkar, Riddhi, Thakkar, Roshni, Thakur, Kiran T, Tokarz, Rafal   +19 more
core   +2 more sources

Targeting Immune Checkpoints: Basic Signaling Pathways and Clinical Translation in Cancer Therapeutics

MedComm – Oncology, Volume 4, Issue 3, September 2025.
Immune checkpoints in tumor immunotherapy. Ligand binding to the receptor inhibits immune cell function, promotes tumor cell immune escape, and suppresses the immune response. The pathways of action are VISTA‐IGSF11, TIM‐3‐Ceacam1, CD47‐SIRPα, CTLA‐4‐CD80/CD86, PD‐L1‐PD‐1, MHC‐1‐LILRB, and CD24 ‐ Siglec ‐10. There are also other immune checkpoints such
Han Sun, Dan Huang, Huiling Zhang, Mingyuan Dong, Simiao Wang, Man Sun, Jiayi Liu, Yiqi Wang, Xiaojie Qu, Xuefeng Li, Zhaogang Yang   +10 more
wiley   +1 more source

Will containment of wild poliovirus in laboratories and inactivated poliovirus vaccine production sites be effective for global certification?

Bulletin of the World Health Organization, 2004
The absolute laboratory containment of any virus cannot be guaranteed, but a wealth of experience indicates that effective containment of wild poliovirus materials for global certification is technically and operationally feasible.
Dowdle Walter R., Wolff Christopher, Sanders Raymond, Lambert Scott, Best Maureen   +4 more
doaj  

Efficacy of commercial disinfectants Virkon®S and Microchem Plus against poliovirus

Journal of Biosafety and Biosecurity
Introduction: The WHO Global Action Plan for Poliovirus Containment, 4th edition (GAPIV) describes the necessary conditions for the containment of poliovirus material in poliovirus-essential facilities (PEFs).
Leesa Bruggink, David Bagnara, Yi Nong, Matthew Kaye, Linda Hobday, Jade McKenzie, Ann Cornish, Bruce Thorley, Chuan Kok Lim   +8 more
doaj   +1 more source

An evaluation of the sensitivity of acute flaccid paralysis surveillance for poliovirus infection in Australia

BMC Infectious Diseases, 2009
Background World Health Organization (WHO) targets for acute flaccid paralysis (AFP) surveillance, including the notification of a minimum rate of AFP among children, are used to assess the adequacy of AFP surveillance for the detection of poliovirus ...
Madin Ben, Kelly Heath, Martin P Anthony J, Watkins Rochelle E, Watson Charles   +4 more
doaj   +1 more source

Few and Far Between: How HIV May Be Evading Antibody Avidity [PDF]

, 2010
No ...
Bjorkman, Pamela J., Klein, Joshua S.
core   +3 more sources

Circulating Vaccine‐Derived Poliovirus Type 2 (cVDPV2) Outbreak Response With Novel Oral Poliovirus Vaccine Type 2 (nOPV2), Sierra Leone's Experience

Public Health Challenges, Volume 4, Issue 3, September 2025.
ABSTRACT Background In March 2024, a circulating vaccine‐derived poliovirus type 2 (cVDPV2) was isolated in environmental samples (ESs) collected at the Mabella Sawmill Bridge environmental surveillance (ES) site. The Ministry of Health and its partners responded to the outbreak by conducting a novel oral poliovirus vaccine type 2 (nOPV2) nationwide ...
Desmond M. Kangbai, Edwin N. Sesay, Nella Clemens‐Kangbai, Andrew K. Kemoh, Sallu Lansana, Hassan Benya, Aminata Nunie, Joyce M. Kallon, Edna G. Samuels, Amanda Clemens, Michael Jones, Braima Patrick Kanneh, Peter B. James, Andrew Alfred Nyakeh Jimmy, Mohamed T. M. Kallay, Tom Sesay   +15 more
wiley   +1 more source

Coalescence of the sites of cowpea mosaic virus RNA replication into a cytopathic structure [PDF]

Cowpea mosaic virus (CPMV) replication induces an extensive proliferation of endoplasmic reticulum (ER) membranes, leading to the formation of small membranous vesicles where viral RNA replication takes place.
Carette, J.E., Gühl, K., Kammen, A., van, Wellink, J.   +3 more
core   +2 more sources

Development of an In‐House Antigen ELISA Using Monoclonal and Polyclonal Antibodies Against an Isolated Canine Distemper Virus

Veterinary Medicine and Science, Volume 11, Issue 5, September 2025.
The present work describes the isolation and characterization of CDV from dogs and its molecular confirmation by RT‐PCR targeting the gene encoding the F protein. Sequencing and phylogenetic analysis were undertaken to determine the strain relatedness of the viral genome.
Serkan Kökkaya, Ayşe Gençay Göksu
wiley   +1 more source

Unleashing the Antiviral Potential of Stapled Peptides: A New Frontier in Combating Human Neurotropic Viral Infections

Microbial Biotechnology, Volume 18, Issue 9, September 2025.
Human neurotropic viruses like SARS‐CoV‐2, HSV, HOPV and RSV pose significant risks due to their ability to invade and persist in the nervous system. Stapled peptides represent a promising therapeutic approach with enhanced stability, target affinity and bioavailability, emerging as an effective strategy for neutralising human neurotropic viruses ...
Sanskruti Patil, Rakesh Rahangdale, Mukesh Pasupuleti, Puttur Santhoshkumar, Raghu Chandrashekar Hariharapura   +4 more
wiley   +1 more source