Results 81 to 90 of about 88,319 (314)
Poliovirus mutant that contains a cold-sensitive defect in viral RNA synthesis [PDF]
By manipulating an infectious cDNA clone of poliovirus, we have introduced a single-codon insertion into the 3A region of the viral genome which has been proposed to encode a functional precursor of the virion-linked protein VPg. The resulting mutant was
Baltimore, David, Bernstein, Harris D.
core
There are currently huge efforts by the World Health Organization and partners to complete global polio eradication. With the significant decline in poliomyelitis cases due to wild poliovirus in recent years, rare cases related to the use of live ...
G. Dunn +5 more
semanticscholar +1 more source
When Public Health Becomes the Weapon: Current and Prospective Consequences of the Genocide in Gaza
ABSTRACT Catastrophic humanitarian conditions during the 2023–2025 genocide in Gaza have caused a public health crisis of exceptional magnitude. This article summarizes key short‐ and long‐term health consequences for Gaza's civilian population and outlines priorities for recovery.
Therese Alexandra Evald +19 more
wiley +1 more source
Poliovirus-specific primer-dependent RNA polymerase able to copy poly(A) [PDF]
A template-dependent RNA polymerase has been isolated from poliovirus-infected cells by assaying for the ability of the enzyme to copy poly(A) complexed to an oligo(U) primer.
Baltimore, David, Flanegan, James B.
core
The role of cellular adhesion molecules in virus attachment and entry [PDF]
As obligate intracellular parasites, viruses must traverse the host-cell plasma membrane to initiate infection. This presents a formidable barrier, which they have evolved diverse strategies to overcome.
Bhella, David
core +1 more source
Abstract Passive environmental DNA (eDNA) sampling is rapidly emerging as a powerful alternative to active sampling methods (e.g. direct water sampling), with a rapidly growing diversity of tested approaches but little methodological convergence.
Fidji Sandré +2 more
wiley +1 more source
Seroprevalence of Poliovirus Antibodies in the United States Population, 2009–2010
Background Polio is eliminated in the United States, with the last indigenous transmission occurring in 1979. However, global eradication of polio has not yet been completed, so importation of poliovirus into the U.S. is still possible.
Gregory S. Wallace +3 more
doaj +1 more source
Delayed kinetics of poliovirus RNA synthesis in a human cell line with reduced levels of hnRNP C proteins. [PDF]
The hnRNP C heterotetramer [(C1(3))C2] binds RNA polymerase II transcripts in the nucleus, along with other proteins of the core hnRNP complex, and plays an important role in mRNA biogenesis and transport.
Brunner, Jo Ellen +3 more
core +1 more source
ABSTRACT Background and Aims Cirrhosis favours infections that can lead to liver decompensation and death. Some of these infections can be prevented by vaccination. This study aimed to evaluate the immune response after HBV, pneumococcal, diphtheria, and tetanus vaccination in cirrhotic patients.
Vincent Haghnejad +10 more
wiley +1 more source
Subversion of cellular autophagosomal machinery by RNA viruses.
Infection of human cells with poliovirus induces the proliferation of double-membraned cytoplasmic vesicles whose surfaces are used as the sites of viral RNA replication and whose origin is unknown.
William T Jackson +6 more
doaj +1 more source

