Results 91 to 100 of about 88,319 (314)

An economic analysis of poliovirus risk management policy options for 2013–2052

BMC Infectious Diseases, 2015
BackgroundThe Global Polio Eradication Initiative plans for coordinated cessation of oral poliovirus vaccine (OPV) after interrupting all wild poliovirus (WPV) transmission, but many questions remain related to long-term poliovirus risk management ...
R. D. Duintjer Tebbens, M. Pallansch, S. Cochi, S. Wassilak, K. Thompson   +4 more
semanticscholar   +1 more source

Engineering the 3′‐UTR of Tobacco Vein Mottling Virus to Confer Cross‐Protection Against Potyviruses

Molecular Plant Pathology, Volume 27, Issue 5, May 2026.
The 3′‐untranslated region (3′‐UTR) and its secondary structure of virus genomic RNA of tobacco vein mottling virus (TVMV) are important in symptoms attenuation, which can be engineered for cross‐protection against further viral infection. We provide experimental evidence that supports the roles of 3′‐UTR in potyvirus infection.
Haijuan Wang, Zhenqi Sun, Baolong Zhang, Zhaoran Wu, Jiaxin Xu, Mingmin Zhao   +5 more
wiley   +1 more source

The Impact of Capsid Proteins on Virus Removal and Inactivation During Water Treatment Processes [PDF]

, 2015
This study examined the effect of the amino acid composition of protein capsids on virus inactivation using ultraviolet (UV) irradiation and titanium dioxide photocatalysis, and physical removal via enhanced coagulation using ferric chloride.
Abbaszadegan, Morteza A., Gerrity, Daniel, Mayer, Brooke K., Yang, Yu   +3 more
core   +3 more sources

CSPG4 Mediates Inflammatory, Cell Death, and Senescence Responses in Enteric Glia Exposed to Clostridioides difficile Toxins

The FASEB Journal, Volume 40, Issue 8, 30 April 2026.
Enteric glia in humans, mice, and rats express all known receptors for TcdA (LDLR) and TcdB (CSPG4, FZD‐1, FZD2, FZD7, PVRL3, TFPI, LRP1). CSPG4 expression is increased in colonic tissues from humans and mice with C. difficile infection, as well as in rat enteric glia exposed to TcdA or TcdB. C.
Francisco M. S. Marques, Deiziane V. S. Costa, Conceição S. M. Rebouças, Gerly A. C. Brito, Cirle A. Warren, Renata F. C. Leitão   +5 more
wiley   +1 more source

Coronavirus Nsp3 Hijacks CLTC to Modulate Autophagosome Nucleation for Promoting DMV Formation and Viral Replication

Advanced Science, Volume 13, Issue 24, 27 April 2026.
In wild‐type cells, FIPV infection recruits CLTC to nsp3, facilitates DMV biogenesis and block autophagic flux to promote viral replication. CLTC knockout impairs autophagosome nucleation by reducing Beclin1–ATG14 complex expression. This disrupts the formation of autophagic precursor membranes, thereby preventing their hijacking by nsp3 for DMV ...
Juan Xu, Hang Li, Peng Liu, Zhe Jiao, Ding Zhang, Zhelin Su, Sai Niu, Jintao Zhang, Yuejun Shi, Guiqing Peng   +9 more
wiley   +1 more source

Three-dimensional structure of poliovirus receptor bound to poliovirus [PDF]

Proceedings of the National Academy of Sciences, 2000
Poliovirus initiates infection by binding to its cellular receptor (Pvr). We have studied this interaction by using cryoelectron microscopy to determine the structure, at 21-Å resolution, of poliovirus complexed with a soluble form of its receptor (sPvr). This density map aided construction of a homology-based model of sPvr and, in conjunction with the
D M, Belnap, B M, McDermott, D J, Filman, N, Cheng, B L, Trus, H J, Zuccola, V R, Racaniello, J M, Hogle, A C, Steven   +8 more
openaire   +2 more sources

Diversity of Rhinovirus and Enterovirus Infections Among Pediatric Patients Hospitalized in Wisconsin, 2022–2023

Journal of Medical Virology, Volume 98, Issue 4, April 2026.
ABSTRACT Severe rhinovirus (RV)/enterovirus (EV) respiratory infections in pediatric patients increased in the US during 2022–2023. This study aimed to characterize RV/EV genetic diversity among hospitalized children in Wisconsin and describe demographic and clinical factors of patients by RV/EV type.
Hannah L. Litwak, Carlos M. Perez, Allen Bateman, Kyley Anhalt, Xiaoyan Lu, Shannon Rogers, Brian Emery, Terry Fei Fan Ng, Caelin Cubenas, Cria O. Gregory, Clinton Paden, Thomas Haupt, Hannah L. Kirking, Hannah E. Segaloff   +13 more
wiley   +1 more source

Isolation and Identification of Polioviruses from Stool Specimens of Suspected Cases

Journal of Rawalpindi Medical College, 2014
Background: To study the isolation and identification of polioviruses from the stool specimen of suspected cases of poliomyelitis (polio). Methods : In this descriptive study two poliovirus-sensitive cell lines of human origin HEp-2, and RD were used for
Inaam Qadir J. Hashmi
doaj   +2 more sources

Coverage, spatial distribution and determinants of childhood inactivated poliovirus vaccine immunization in Ethiopia.

PLoS ONE
IntroductionPolio eradication is a current and common strategy throughout the globe. The study of the newly introduced inactivated poliovirus vaccine provides a grasp on the current status of immunization and identifies any disparities in the ...
Tadesse Tarik Tamir, Belayneh Shetie Workneh, Enyew Getaneh Mekonen, Alebachew Ferede Zegeye   +3 more
doaj   +1 more source

Epidemiological and Clinical Characteristics of the Enterovirus D68 Outbreak in Spain in 2024

Journal of Medical Virology, Volume 98, Issue 4, April 2026.
ABSTRACT Enterovirus D68 (EV‐D68) is a significant cause of respiratory and neurological disease worldwide. In 2024, Spain experienced its largest recorded EV‐D68 outbreak, accounting for 37.4% of all typed EV (294/892). This study describes the epidemiological, clinical, and phylogenetic features of EV‐D68 infections.
Juan Camacho, Nerea García‐Ibáñez, María Dolores Fernández‐García, Yasmin Biya, Estrella Ruiz de Pedro, Almudena Gutiérrez, María Carmen Nieto, María Montserrat Ruiz‐García, María Teresa Pastor‐Fajardo, Eduardo Lagarejos, Carlos de Leonardo Simón, Ana Navascués, Antonio Moreno‐Docón, Mónica Gozalo‐Marguello, Carla Berengua, Pedro Antequera, María Dolores Huéscar‐Pascual, Cristina Calvo, María Cabrerizo   +18 more
wiley   +1 more source