Addressing the inactivated poliovirus vaccine shortage
Lancet, The, 2019Roland W Sutter, Michel Zaffran
exaly +3 more sources
Seventy eight infants aged 6-8 weeks received either two doses of 0.1 ml of inactivated poliovirus vaccine (IPV) intradermally 8 weeks apart (group A) or three doses 4 weeks apart (group B).
Thomas Cherian, P Raghupathy, T J John
exaly +2 more sources
Vaccination with Inactivated Poliovirus Vaccine and Oral Poliovirus Vaccine in Denmark
Clinical Infectious Diseases, 1984In Denmark a polio vaccination program including both inactivated poliovirus vaccine (IPV) and oral poliovirus vaccine ( OPV ) has been in use since 1968. Three injections of IPV are given when the children are five, six, and 15 months of age. Subsequently, three vaccinations with trivalent OPV are administered at the age of three, four, and five years.
H, von Magnus, I, Petersen
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Humoral and intestinal immunity induced by new schedules of bivalent oral poliovirus vaccine and one or two doses of inactivated poliovirus vaccine in Latin American infants: an open-label randomised controlled trial [PDF]
© 2016 Elsevier Ltd Background Replacement of the trivalent oral poliovirus vaccine (tOPV) with bivalent types 1 and 3 oral poliovirus vaccine (bOPV) and global introduction of inactivated poliovirus vaccine (IPV) are major steps in the polio endgame ...
Edwin J Asturias +2 more
exaly +2 more sources
In The Netherlands the inactivated poliovirus vaccine (IPV) is used for protection against poliomyelitis. It is not clear if parenteral vaccination with IPV can lead to priming of the mucosal immune system. We developed and evaluated enzyme-linked immunosorbent assays for the detection of poliovirus serotype-specific immunoglobulin A (IgA) and ...
Herremans, MMPT +6 more
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Efficacy and safety of oral poliovirus vaccine and inactivated poliovirus vaccine
Pediatric Infectious Disease, 1991Inactivated poliovirus vaccine (IPV) is the vaccine of choice for protection against paralytic poliomyelitis provided that it is used within the context of a program to increase and sustain the level of uptake to as close to 100% as possible. This means targeting the disadvantaged in society as well as those who have their own pediatrician. The reasons
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Comparison of Inactivated Poliovirus Vaccine and Oral Poliovirus Vaccine Programs in Israel
Clinical Infectious Diseases, 1984In spite of high vaccination coverage, paralytic poliomyelitis still occurs in Israel, either in sporadic form in the urban area or in small outbreaks in the rural, non-Jewish segment. At high risk are mainly very young infants, not yet protected by poliovirus vaccine and children who have failed to seroconvert after a full course of oral poliovirus ...
T A, Swartz +4 more
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Fractional Doses of Inactivated Poliovirus Vaccine in Oman
New England Journal of Medicine, 2010We conducted a clinical trial of fractional doses of inactivated poliovirus vaccine administered to infants in Oman, in order to evaluate strategies for making the vaccine affordable for use in developing countries.We compared fractional doses of inactivated poliovirus vaccine (0.1 ml, representing one fifth of a full dose) given intradermally with the
Mohammed, AJ +12 more
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Sequential Use of Inactivated Poliovirus Vaccine followed by Oral Poliovirus Vaccine in Oman
Journal of Infectious Diseases, 1997Seroprevalence and geometric mean titers (GMTs) were compared at 6 and 10 months after vaccination with monovalent type 1 oral poliovirus vaccine (OPV) at 6 months and trivalent OPV at 7 and 9 months. Group 1 had received 4 doses of OPV, group 2 OPV at birth and 3 doses of OPV and inactivated poliovirus vaccine (IPV), and group 3 placebo at birth and 3
R W, Sutter +9 more
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Use of inactivated poliovirus vaccine for poliovirus outbreak response
The Lancet Infectious DiseasesWith continued wild poliovirus transmission in Afghanistan and Pakistan and circulating vaccine-derived poliovirus in certain countries, there exists an ongoing risk of importation of polioviruses into other countries, including those that have been polio-free for decades.
Ananda S, Bandyopadhyay +7 more
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