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Efficacy and safety of oral poliovirus vaccine and inactivated poliovirus vaccine

Pediatric Infectious Disease, 1991
Inactivated poliovirus vaccine (IPV) is the vaccine of choice for protection against paralytic poliomyelitis provided that it is used within the context of a program to increase and sustain the level of uptake to as close to 100% as possible. This means targeting the disadvantaged in society as well as those who have their own pediatrician. The reasons
openaire   +2 more sources

Comparison of Inactivated Poliovirus Vaccine and Oral Poliovirus Vaccine Programs in Israel

Clinical Infectious Diseases, 1984
In spite of high vaccination coverage, paralytic poliomyelitis still occurs in Israel, either in sporadic form in the urban area or in small outbreaks in the rural, non-Jewish segment. At high risk are mainly very young infants, not yet protected by poliovirus vaccine and children who have failed to seroconvert after a full course of oral poliovirus ...
T A, Swartz   +4 more
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Fractional Doses of Inactivated Poliovirus Vaccine in Oman

New England Journal of Medicine, 2010
We conducted a clinical trial of fractional doses of inactivated poliovirus vaccine administered to infants in Oman, in order to evaluate strategies for making the vaccine affordable for use in developing countries.We compared fractional doses of inactivated poliovirus vaccine (0.1 ml, representing one fifth of a full dose) given intradermally with the
Mohammed, AJ   +12 more
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Use of inactivated poliovirus vaccine for poliovirus outbreak response

The Lancet Infectious Diseases
With continued wild poliovirus transmission in Afghanistan and Pakistan and circulating vaccine-derived poliovirus in certain countries, there exists an ongoing risk of importation of polioviruses into other countries, including those that have been polio-free for decades.
Ananda S, Bandyopadhyay   +7 more
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Sequential Use of Inactivated Poliovirus Vaccine followed by Oral Poliovirus Vaccine in Oman

Journal of Infectious Diseases, 1997
Seroprevalence and geometric mean titers (GMTs) were compared at 6 and 10 months after vaccination with monovalent type 1 oral poliovirus vaccine (OPV) at 6 months and trivalent OPV at 7 and 9 months. Group 1 had received 4 doses of OPV, group 2 OPV at birth and 3 doses of OPV and inactivated poliovirus vaccine (IPV), and group 3 placebo at birth and 3
R W, Sutter   +9 more
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Inactivated poliovirus vaccine and the final stages of poliovirus eradication

Vaccine, 2001
The use of the inactivated poliovirus vaccine (IPV) will increase before and probably also after the global eradication of the wild type poliovirus. Before eradication, the switch from the use of oral poliovirus vaccine (OPV) to IPV has been due to the better safety record of IPV. Introduction of IPV in the regular immunisation schedules is made easier
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Adjuvanticity of stearyl tyrosine on inactivated poliovirus vaccine

Vaccine, 1986
Preliminary studies of some of the properties of stearyl tyrosine have shown that it is non-toxic, free of adverse reactions at the sites of injection, non-pyrogenic, stable upon storage and easy to sterilize. Formalin inactivated poliovirus vaccine (IPV) adjuvanted with stearyl tyrosine hydrochloride induced significantly higher titres of antibodies ...
S, Landi   +5 more
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Inactivated Poliovirus Vaccine

Human Vaccines, 2007
Subhash C, Arya, Nirmala, Agarwal
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[Inactivated poliovirus vaccine].

Nihon rinsho. Japanese journal of clinical medicine, 2011
During the final stage of global polio eradication program, universal use of inactivated poliovirus vaccine (IPV) is the most feasible option to minimize the inherent risk of oral poliovirus vaccine (OPV), such as vaccine-associated paralytic poliomyelitis (VAPP) and polio outbreaks due to vaccine-derived polioviruses.
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Poliovirus Vaccine—Inactivated

2023
Emmanuel J. Vidor, John F. Modlin
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