Results 1 to 10 of about 42,414 (275)

Prolonged Excretion of Poliovirus among Individuals with Primary Immunodeficiency Disorder: An Analysis of the World Health Organization Registry [PDF]

Frontiers in Immunology, 2017
Individuals with primary immunodeficiency disorder may excrete poliovirus for extended periods and will constitute the only remaining reservoir of virus after eradication and withdrawal of oral poliovirus vaccine.
Grace Macklin, Yi Liao, Yi Liao, Marina Takane, Kathleen Dooling, Stuart Gilmour, Ondrej Mach, Olen M. Kew, Olen M. Kew, Roland W. Sutter, The iVDPV Working Group, Ousmane Diop, Nicksy Gumede Moeletsi, Raffaella Williams, Mohamed Seghier, Francis Delpeyroux, Gloria Rey Benito, Maria Cecilia Freire, Cara Burns, Humayun Asghar, Salman Sharif, Jagadish Deshpande, Shohreh Shahmahmoodi, Henda Triki, Laila E Bassioni, Amina Al-Jardani, Eugene Merav Weil Gavrilin, Javier Martín, Sirima Pattamadilok, Sunethra Gunasena, Yan Zhang, Wenbo Xu   +31 more
doaj   +3 more sources

Complexity of options related to restarting oral poliovirus vaccine (OPV) in national immunization programs after OPV cessation [version 1; peer review: 1 approved, 2 approved with reservations]

Gates Open Research, 2023
Background: The polio eradication endgame continues to increase in complexity.  With polio cases caused by wild poliovirus type 1 and circulating vaccine-derived polioviruses of all three types (1, 2 and 3) reported in 2022, the number, formulation, and ...
Steven GF Wassilak, Dominika A Kalkowska, Concepcion F Estivariz, Eric Wiesen, Kimberly M Thompson, Cara C Burns, Kamran Badizadegan   +6 more
doaj   +2 more sources

Poliovirus shedding after sequential immunization of Sabin-strain inactivated polio vaccines and oral attenuated polio vaccines [PDF]

npj Vaccines
The identification of poliovirus in stool samples post-Oral Poliovirus Vaccine (OPV) immunization is essential for implementing post-eradication monitoring of poliomyelitis.
Yuting Fu, Rufei Ma, Zhimei Zhao, Zhaojun Mo, Zhifang Ying, Jing Li, Hui Ye, Guoliang Li, Xiaochang Liu, Jiangli Liang, Ling Ping, Jingyan Li, Junhui Tao, Qinghai Yang, Dingkai Wei, Li Yi, Hongbo Chen, Jianfeng Wang, Ruiju Jiang, Lei Yu, Wei Cai, Wei Yang, Lei Yue, Mingxue Xie, Qiongzhou Yin, Jing Pu, Chao Hong, Lukui Cai, Yan Deng, Jiana Wen, Yan Ma, Na Gao, Xiaoyu Wang, Hongwei Liao, Qiuyan Ji, Guang Ji, Wenzhu Hu, Qin Gu, Xiaoyue He, Han Chu, Yixian Fu, Jian Zhou, Yu Wen, Xiaolei Yang, Changgui Li, Li Shi, Ting Zhao, Teng Huang, Jingsi Yang   +48 more
doaj   +2 more sources

Immunogenicity and safety evaluation of bivalent types 1 and 3 oral poliovirus vaccine by comparing different poliomyelitis vaccination schedules in China: A randomized controlled non-inferiority clinical trial

Human Vaccines & Immunotherapeutics, 2017
Background: The type 2 component of the oral poliovirus vaccine is targeted for global withdrawal through a switch from the trivalent oral poliovirus vaccine (tOPV) to a bivalent oral poliovirus vaccine (bOPV). The switch is intended to prevent paralytic
Jingjun Qiu, Yunkai Yang, Lirong Huang, Ling Wang, Zhiwei Jiang, Jian Gong, Wei Wang, Hongyan Wang, Shaohong Guo, Chanjuan Li, Shuyuan Wei, Zhaojun Mo, Jielai Xia   +12 more
doaj   +2 more sources

Intestinal antibody responses to a live oral poliovirus vaccine challenge among adults previously immunized with inactivated polio vaccine in Sweden

BMJ Global Health, 2019
Background Our understanding of the acquisition of intestinal mucosal immunity and the control of poliovirus replication and transmission in later life is still emerging.Methods As part of a 2011 randomised, blinded, placebo-controlled clinical trial of ...
Elizabeth B Brickley, Ruth I Connor, Wendy F Wieland-Alter, Marc S Collett, Marianne Hartford, Harrie Van Der Avoort, Austin W Boesch, Joshua A Weiner, Margaret E Ackerman, Mark A McKinlay, Minetaro Arita, Ananda S Bandyopadhyay, John F Modlin, Peter F Wright   +13 more
doaj   +2 more sources

Advances and challenges in poliomyelitis vaccines: a comprehensive review of development, production, and global deployment [PDF]

Frontiers in Public Health
Poliomyelitis has been a significant global health challenge for centuries. Since the launch of the Global Polio Eradication Initiative (GPEI) in 1988, remarkable progress has been achieved, with wild poliovirus (WPV) cases reduced by over 99%.
Jia Liang, Qi Zhang, Yanan Li, Lili Wang
doaj   +2 more sources

Excretion and clearance of Sabin-like type 3 poliovirus in a child diagnosed with severe combined immunodeficiency [PDF]

Human Vaccines & Immunotherapeutics
Children with primary immunodeficiency disorder (PID) are at higher risk of developing vaccine-associated paralytic poliomyelitis (VAPP) or vaccine-derived polioviruses (VDPV) infection when inadvertently expose to poliovirus vaccine, oral (OPV). A pilot
Ning Yao, Yang Liu, Zhi-Yong Zhang, Min Tian, Wu-Juan Xie, Hua Zhao, Hong Yang, Lance E. Rodewald, Ning Wen, Zun-Dong Yin, Fu-Zhen Wang, Qing Wang, Jia-Wei Xu   +12 more
doaj   +2 more sources

Population Immunity against Serotype-2 Poliomyelitis Leading up to the Global Withdrawal of the Oral Poliovirus Vaccine: Spatio-temporal Modelling of Surveillance Data. [PDF]

PLoS Medicine, 2016
BACKGROUND: Global withdrawal of serotype-2 oral poliovirus vaccine (OPV2) took place in April 2016. This marked a milestone in global polio eradication and was a public health intervention of unprecedented scale, affecting 155 countries.
Blake, Isobel M, Etsano, Andrew, Grassly, Nicholas C, Jafari, Hamid, Molodecky, Natalie A, O'Reilly, Kathleen M, Pons-Salort, Margarita, Safdar, Rana M, Vaz, Rui Gama, Wadood, Mufti Zubair   +9 more
core   +5 more sources

Looking back at prospective modeling of outbreak response strategies for managing global type 2 oral poliovirus vaccine (OPV2) cessation

Frontiers in Public Health, 2023
Introduction Detection of poliovirus transmission and ongoing oral poliovirus vaccine (OPV) use continue to delay poliomyelitis eradication. In 2016, the Global Polio Eradication Initiative (GPEI) coordinated global cessation of type 2 OPV (OPV2) for ...
K. Thompson, D. A. Kalkowska, K. Badizadegan   +2 more
semanticscholar   +1 more source

Poliomyelitis amidst the COVID-19 pandemic in Africa: Efforts, challenges and recommendations

Clinical Epidemiology and Global Health, 2022
Poliomyelitis is the leading infectious cause of acute flaccid paralysis among children under five years of age, caused by the Wild Poliovirus, with no medical cure other than prevention through vaccination.
Olivier Uwishema, Emmanuel Ebuka Elebesunu, Oumnia Bouaddi, Arushi Kapoor, Samaa Akhtar, Fortune Benjamin Effiong, Adhiraj Chaudhary, Helen Onyeaka   +7 more
doaj   +1 more source