Ending Use of Oral Poliovirus Vaccine - A Difficult Move in the Polio Endgame.
Ending Use of Oral Poliovirus Vaccine The global health community has taken the first step toward eliminating use of oral poliovirus vaccine: switching from trivalent to bivalent vaccine.
M. Pallansch
semanticscholar +1 more source
Vaccination plays a crucial role in mediating protection against infectious diseases, but immune responses to vaccination are highly variable and frequently sub‐optimal in vulnerable populations. Here, we review the latest preclinical and clinical evidence demonstrating that the gut microbiota plays a significant role in regulating immune responses to ...
Charné Rossouw +2 more
wiley +1 more source
Seroepidemiology: an underused tool for designing and monitoring vaccination programmes in low- and middle-income countries. [PDF]
Seroepidemiology, the use of data on the prevalence of bio-markers of infection or vaccination, is a potentially powerful tool to understand the epidemiology of infection before vaccination and to monitor the effectiveness of vaccination programmes ...
Cutts, Felicity T, Hanson, Matt
core +2 more sources
Problems in the development and use of oral poliovirus vaccine
I am highly honored to be one of the recipients of the Oscar B. Hunter Memorial Award. The esteem of one's colleagues is the greatest reward for a scientist. For the scientist realizes, as Aristotle pointed out long ago, that each one at best can add but a little to our knowledge of Nature, and that the real grandeur arises only from all the assembled ...
openaire +4 more sources
Metastatic brain tumors: from development to cutting‐edge treatment
This abstract briefly reviews the diagnosis and treatment of brain metastases from lung cancer and breast cancer, the progress of artificial intelligence and multiomics. Importantly, we focus on the pathogenesis of brain metastases and the tumor microenvironment to seek treatment strategies.
Guilong Tanzhu +7 more
wiley +1 more source
Trends and measurement of HIV prevalence in northern Malawi.
BACKGROUND: Most data on HIV prevalence in Malawi come from antenatal clinic (ANC) surveillance and are, therefore, subject to bias. OBJECTIVES: HIV prevalence and risk factors were measured using population-based data to assess the accuracy of ANC ...
Crampin, Amelia C +6 more
core +1 more source
Role of Serial Polio Seroprevalence Studies in Guiding Implementation of the Polio Eradication Initiative in Kano, Nigeria: 2011-2014. [PDF]
BACKGROUND: Nigeria was one of 3 polio-endemic countries before it was de-listed in September 2015 by the World Health Organization, following interruption of transmission of the poliovirus. During 2011-2014, Nigeria conducted serial polio seroprevalence
Abdullahi Walla +19 more
core +1 more source
Tissue‐resident memory T cells in diseases and therapeutic strategies
Tissue‐resident memory T (TRM) cells are crucial components of the immune system and play vital roles in antiviral, antibacterial, and antitumor immunity, as well as chronic inflammation conditions and graft‐versus‐host diseases. Understanding the intricate regulation of TRM cells is crucial for developing targeted therapeutic strategies, such as ...
Daoyuan Xie +4 more
wiley +1 more source
Vaccine coverage and determinants of incomplete vaccination in children aged 12-23 months in dschang, west region, cameroon: a cross-sectional survey during a polio outbreak [PDF]
Inadequate immunization coverage with increased risk of vaccine preventable diseases outbreaksremains a problem in Africa. Moreover, different factors contribute to incomplete vaccination status. This study wasperformed in Dschang (West Region, Cameroon),
Biguioh, Rodrigue Mabvouna +8 more
core +2 more sources
Background A new Sabin strain inactivated poliovirus vaccine (sIPV) proved to be immunogenic and safe in all IPV primary immunization in the previous study, with the corresponding profiles in sequential immunizations unclear.
Yuemei Hu +10 more
semanticscholar +1 more source

