Results 71 to 80 of about 15,408 (221)

Circulating Vaccine‐Derived Poliovirus Type 2 (cVDPV2) Outbreak Response With Novel Oral Poliovirus Vaccine Type 2 (nOPV2), Sierra Leone's Experience

open access: yesPublic Health Challenges, Volume 4, Issue 3, September 2025.
ABSTRACT Background In March 2024, a circulating vaccine‐derived poliovirus type 2 (cVDPV2) was isolated in environmental samples (ESs) collected at the Mabella Sawmill Bridge environmental surveillance (ES) site. The Ministry of Health and its partners responded to the outbreak by conducting a novel oral poliovirus vaccine type 2 (nOPV2) nationwide ...
Desmond M. Kangbai   +15 more
wiley   +1 more source

Determination of Factors Affecting Bivalent (Type 1 and 3) Stability of Oral Poliomyelitis Vaccine

open access: yesMedical Laboratory Journal, 2020
Background and objectives: After using of trivalent oral poliovirus vaccine (OPV) for a long time in Iran, in recent years, due to the eradication of type 2 of poliovirus, a bivalent vaccine containing types 1 and 3 is used.
Sina Soleimani
doaj  

Seroepidemiology: an underused tool for designing and monitoring vaccination programmes in low- and middle-income countries. [PDF]

open access: yes, 2016
Seroepidemiology, the use of data on the prevalence of bio-markers of infection or vaccination, is a potentially powerful tool to understand the epidemiology of infection before vaccination and to monitor the effectiveness of vaccination programmes ...
Cutts, Felicity T, Hanson, Matt
core   +2 more sources

Unleashing the Antiviral Potential of Stapled Peptides: A New Frontier in Combating Human Neurotropic Viral Infections

open access: yesMicrobial Biotechnology, Volume 18, Issue 9, September 2025.
Human neurotropic viruses like SARS‐CoV‐2, HSV, HOPV and RSV pose significant risks due to their ability to invade and persist in the nervous system. Stapled peptides represent a promising therapeutic approach with enhanced stability, target affinity and bioavailability, emerging as an effective strategy for neutralising human neurotropic viruses ...
Sanskruti Patil   +4 more
wiley   +1 more source

Vaccine-Derived Poliovirus Infection among Patients with Primary Immunodeficiency and Effect of Patient Screening on Disease Outcomes, Iran

open access: yesEmerging Infectious Diseases, 2019
Patients with immunodeficiency-associated vaccine-derived poliovirus (iVDPV) are potential poliovirus reservoirs in the posteradication era that might reintroduce polioviruses into the community.
Mohammadreza Shaghaghi   +16 more
doaj   +1 more source

Increasing Occurrence of Marburg Virus Outbreaks in Africa: Risk Assessment for Public Health

open access: yesMicrobial Biotechnology, Volume 18, Issue 9, September 2025.
Bat and Marburg virus (Filovirus). Left: A Rousettus aegyptiacus bat; Center: a distribution map of R. aegyptiacus; Right: EM of Marburg virus. (figure credits: Left Wikipedia Nilflughund Lithuanian Zoological Gardens, Center; Center: Wikipedia Nilflughund IUCN Red List of Threatened Species, right Wikipedia Marburg virus CDC Fred Murphy; J.
Harald Brüssow
wiley   +1 more source

Rectal Microbiome Composition Correlates with Humoral Immunity to HIV-1 in Vaccinated Rhesus Macaques. [PDF]

open access: yes, 2019
The microbiome is an integral and dynamic component of the host and is emerging as a critical determinant of immune responses; however, its influence on vaccine immunogenicity is largely not well understood.
Dinasarapu, Ashok R   +9 more
core   +1 more source

The role of the gut microbiota in regulating responses to vaccination: current knowledge and future directions

open access: yesThe FEBS Journal, Volume 292, Issue 6, Page 1480-1499, March 2025.
Vaccination plays a crucial role in mediating protection against infectious diseases, but immune responses to vaccination are highly variable and frequently sub‐optimal in vulnerable populations. Here, we review the latest preclinical and clinical evidence demonstrating that the gut microbiota plays a significant role in regulating immune responses to ...
Charné Rossouw   +2 more
wiley   +1 more source

Macaque models of human infectious disease. [PDF]

open access: yes, 2008
Macaques have served as models for more than 70 human infectious diseases of diverse etiologies, including a multitude of agents-bacteria, viruses, fungi, parasites, prions.
Abe   +330 more
core   +1 more source

Metastatic brain tumors: from development to cutting‐edge treatment

open access: yesMedComm, Volume 6, Issue 1, January 2025.
This abstract briefly reviews the diagnosis and treatment of brain metastases from lung cancer and breast cancer, the progress of artificial intelligence and multiomics. Importantly, we focus on the pathogenesis of brain metastases and the tumor microenvironment to seek treatment strategies.
Guilong Tanzhu   +7 more
wiley   +1 more source

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