Results 51 to 60 of about 6,425 (167)

Limited duration of vaccine poliovirus and other enterovirus excretion among human immunodeficiency virus infected children in Kenya

open access: yesBMC Infectious Diseases, 2009
Background Immunodeficient persons with persistent vaccine-related poliovirus infection may serve as a potential reservoir for reintroduction of polioviruses after wild poliovirus eradication, posing a risk of their further circulation in inadequately ...
Tukei Peter   +9 more
doaj   +1 more source

Trained Immunity in Childhood Vaccination

open access: yesActa Paediatrica, EarlyView.
Trained immunity as an emerging concept in paediatric vaccinology. Trained immunity links vaccine stimuli through epigenetic and metabolic reprogramming to enhanced innate immune cell function, thereby strengthening protection against diverse pathogens while promoting adaptive immune responses through more efficient antigen presentation and co ...
ChenRongRong Cai   +2 more
wiley   +1 more source

Sabin and wild type polioviruses from children who presented with acute flaccid paralysis in Nigeria [PDF]

open access: yes, 2013
Background: Sensitive poliovirus surveillance to detect vaccine-derived-polioviruses will continue to increase in importance. Objective: Isolating and identifying poliovirus strains from children of pediatrics age in Nigeria.
Okonko, IO, Adu, FD, Adedeji, AO
core   +4 more sources

Therapeutic potential of natural products in cancer immunotherapy: Advances and challenges

open access: yesBritish Journal of Pharmacology, EarlyView.
This review systematically outlines the mechanisms underlying tumour immunotherapy resistance and elucidates the role of natural products in enhancing therapeutic efficacy as immunomodulatory adjuvants. Abstract Immunotherapy has emerged as a clinically pivotal approach in cancer treatment, but its application remains limited to a small subset of ...
Rao Hu   +6 more
wiley   +1 more source

Studies on the Interference Between Group B Coxsackie Viruses and Polioviruses 3. Studies in Tissue Culture. [PDF]

open access: yes, 1964
In the previous papers, the author reported the suppression of multiplication of type 1 and 2 polioviruses by Cox. B 5 in human intestines. The present report describes the interference between polioviruses, having different virulences, and group B ...
浦澤, 正三
core   +1 more source

Population Immunity and Polio Eradication

open access: yesPathogens
The Global Polio Eradication Initiative made immense progress after its establishment in 1988 as a consequence of high coverage with various poliovirus vaccines in all populations of the world.
Paul E. M. Fine
doaj   +1 more source

Acute Flaccid Myelitis: Something Old and Something New

open access: yesmBio, 2019
Since 2014, acute flaccid myelitis (AFM), a long-recognized condition associated with polioviruses, nonpolio enteroviruses, and various other viral and nonviral causes, has been reemerging globally in epidemic form.
David M. Morens   +2 more
doaj   +1 more source

Unmasking the Influence of Viral Micro‐RNAs on Host Immunity

open access: yesImmunology &Cell Biology, EarlyView.
Viral micro‐RNAs are increasingly recognized as key modulators of host–virus interactions. They influence multiple immune functions, including antigen presentation, T‐cell activation, and cytokine signaling, while also tuning viral gene expression to promote persistence.
Riley J. K. Easton   +1 more
wiley   +1 more source

Absence of poliovirus in apparently healthy school children in Bauchi state, Nigeria

open access: yesJournal of Infection in Developing Countries, 2016
Introduction: Poliovirus infections have been established to be in circulation in the remaining three polio-endemic nations. These pathogens have been associated with several chronic diseases, particularly acute flaccid paralysis of children. This study
Idris Abdullahi Nasir   +2 more
doaj   +1 more source

Next generation inactivated polio vaccine manufacturing to support post polio-eradication biosafety goals. [PDF]

open access: yesPLoS ONE, 2013
Worldwide efforts to eradicate polio caused a tipping point in polio vaccination strategies. A switch from the oral polio vaccine, which can cause circulating and virulent vaccine derived polioviruses, to inactivated polio vaccines (IPV) is scheduled ...
Yvonne E Thomassen   +5 more
doaj   +1 more source

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