Results 71 to 80 of about 8,665 (215)

Vaccine-related poliovirus shedding in trivalent polio vaccine and human immunodeficiency virus status: analysis from under five children

BMC Research Notes, 2017
Background Poliomyelitis is an acute viral infection caused by poliovirus and transmitted via the fecal–oral route. The causative agent is one of the three serotypes of poliovirus (serotypes 1, 2, 3) that differ slightly in capsid protein.
Joanne Hassan, Laura Wangai, Peter Borus, Christopher Khayeka–Wandabwa, Lucy Wanja Karani, Mercy Kithinji, Michael Kiptoo   +6 more
doaj   +1 more source

CSPG4 Mediates Inflammatory, Cell Death, and Senescence Responses in Enteric Glia Exposed to Clostridioides difficile Toxins

The FASEB Journal, Volume 40, Issue 8, 30 April 2026.
Enteric glia in humans, mice, and rats express all known receptors for TcdA (LDLR) and TcdB (CSPG4, FZD‐1, FZD2, FZD7, PVRL3, TFPI, LRP1). CSPG4 expression is increased in colonic tissues from humans and mice with C. difficile infection, as well as in rat enteric glia exposed to TcdA or TcdB. C.
Francisco M. S. Marques, Deiziane V. S. Costa, Conceição S. M. Rebouças, Gerly A. C. Brito, Cirle A. Warren, Renata F. C. Leitão   +5 more
wiley   +1 more source

Viral Aetiology of Acute Flaccid Paralysis Surveillance Cases, before and after Vaccine Policy Change from Oral Polio Vaccine to Inactivated Polio Vaccine

Journal of Tropical Medicine, 2014
Since 1992, surveillance for acute flaccid paralysis (AFP) cases was introduced in Malaysia along with the establishment of the National Poliovirus Laboratory at the Institute for Medical Research.
T. S. Saraswathy Subramaniam, Mohd Apandi Apandi, Rohani Jahis, Mohd Samsul Samsudin, Zainah Saat   +4 more
doaj   +1 more source

Coronavirus Nsp3 Hijacks CLTC to Modulate Autophagosome Nucleation for Promoting DMV Formation and Viral Replication

Advanced Science, Volume 13, Issue 24, 27 April 2026.
In wild‐type cells, FIPV infection recruits CLTC to nsp3, facilitates DMV biogenesis and block autophagic flux to promote viral replication. CLTC knockout impairs autophagosome nucleation by reducing Beclin1–ATG14 complex expression. This disrupts the formation of autophagic precursor membranes, thereby preventing their hijacking by nsp3 for DMV ...
Juan Xu, Hang Li, Peng Liu, Zhe Jiao, Ding Zhang, Zhelin Su, Sai Niu, Jintao Zhang, Yuejun Shi, Guiqing Peng   +9 more
wiley   +1 more source

Role of environmental poliovirus surveillance in global polio eradication and beyond [PDF]

, 2017
Environmental poliovirus surveillance (ENV) means monitoring of poliovirus (PV) transmission in human populations by examining environmental specimens supposedly contaminated by human faeces.
DE GOURVILLE, E. M., DESHPANDE, J., HOVI, T., ROIVAINEN, M., SHULMAN, L. M., VAN DER AVOORT, H.   +5 more
core  

Acute Flaccid Myelitis: Something Old and Something New

mBio, 2019
Since 2014, acute flaccid myelitis (AFM), a long-recognized condition associated with polioviruses, nonpolio enteroviruses, and various other viral and nonviral causes, has been reemerging globally in epidemic form.
David M. Morens, Gregory K. Folkers, Anthony S. Fauci   +2 more
doaj   +1 more source

Diversity of Rhinovirus and Enterovirus Infections Among Pediatric Patients Hospitalized in Wisconsin, 2022–2023

Journal of Medical Virology, Volume 98, Issue 4, April 2026.
ABSTRACT Severe rhinovirus (RV)/enterovirus (EV) respiratory infections in pediatric patients increased in the US during 2022–2023. This study aimed to characterize RV/EV genetic diversity among hospitalized children in Wisconsin and describe demographic and clinical factors of patients by RV/EV type.
Hannah L. Litwak, Carlos M. Perez, Allen Bateman, Kyley Anhalt, Xiaoyan Lu, Shannon Rogers, Brian Emery, Terry Fei Fan Ng, Caelin Cubenas, Cria O. Gregory, Clinton Paden, Thomas Haupt, Hannah L. Kirking, Hannah E. Segaloff   +13 more
wiley   +1 more source

Absence of poliovirus in apparently healthy school children in Bauchi state, Nigeria

Journal of Infection in Developing Countries, 2016
Introduction: Poliovirus infections have been established to be in circulation in the remaining three polio-endemic nations. These pathogens have been associated with several chronic diseases, particularly acute flaccid paralysis of children. This study
Idris Abdullahi Nasir, Muhammad Sagir Shehu, Yunusa Thairu   +2 more
doaj   +1 more source

Next generation inactivated polio vaccine manufacturing to support post polio-eradication biosafety goals. [PDF]

PLoS ONE, 2013
Worldwide efforts to eradicate polio caused a tipping point in polio vaccination strategies. A switch from the oral polio vaccine, which can cause circulating and virulent vaccine derived polioviruses, to inactivated polio vaccines (IPV) is scheduled ...
Yvonne E Thomassen, Aart G van 't Oever, Monique G C T van Oijen, René H Wijffels, Leo A van der Pol, Wilfried A M Bakker   +5 more
doaj   +1 more source

Epidemiological and Clinical Characteristics of the Enterovirus D68 Outbreak in Spain in 2024

Journal of Medical Virology, Volume 98, Issue 4, April 2026.
ABSTRACT Enterovirus D68 (EV‐D68) is a significant cause of respiratory and neurological disease worldwide. In 2024, Spain experienced its largest recorded EV‐D68 outbreak, accounting for 37.4% of all typed EV (294/892). This study describes the epidemiological, clinical, and phylogenetic features of EV‐D68 infections.
Juan Camacho, Nerea García‐Ibáñez, María Dolores Fernández‐García, Yasmin Biya, Estrella Ruiz de Pedro, Almudena Gutiérrez, María Carmen Nieto, María Montserrat Ruiz‐García, María Teresa Pastor‐Fajardo, Eduardo Lagarejos, Carlos de Leonardo Simón, Ana Navascués, Antonio Moreno‐Docón, Mónica Gozalo‐Marguello, Carla Berengua, Pedro Antequera, María Dolores Huéscar‐Pascual, Cristina Calvo, María Cabrerizo   +18 more
wiley   +1 more source