Results 81 to 90 of about 6,425 (167)

Polioviruses and other enteroviruses isolated from faecal samples of patients with acute flaccid paralysis in Australia, 1996-2004

, 2006
Background: Acute flaccid paralysis (AFP) is the most common clinical presentation of acute poliovirus infection, occurring in 0.1-1% of infected cases. AFP surveillance has been used world-wide to monitor the control and eradication of circulating wild ...
Thorley, B., Kelly, H., Pearn, J. H., Lawrence, A., Brussen, K. A., Elliot, E.   +5 more
core   +1 more source

Patients with Primary Immunodeficiencies Are a Reservoir of Poliovirus and a Risk to Polio Eradication

Frontiers in Immunology, 2017
Immunodeficiency-associated vaccine-derived polioviruses (iVDPVs) have been isolated from primary immunodeficiency (PID) patients exposed to oral poliovirus vaccine (OPV).
Asghar Aghamohammadi, Hassan Abolhassani, Necil Kutukculer, Steve G. Wassilak, Mark A. Pallansch, Samantha Kluglein, Jessica Quinn, Roland W. Sutter, Xiaochuan Wang, Ozden Sanal, Tatiana Latysheva, Aydan Ikinciogullari, Ewa Bernatowska, Irina A. Tuzankina, Beatriz T. Costa-Carvalho, Jose Luis Franco, Raz Somech, Elif Karakoc-Aydiner, Surjit Singh, Liliana Bezrodnik, Francisco J. Espinosa-Rosales, Anna Shcherbina, Yu-Lung Lau, Yu-Lung Lau, Shigeaki Nonoyama, Fred Modell, Vicki Modell, The JMF Centers Network Investigators and Study Collaborators, Mohamed-Ridha Barbouche, Mark A. McKinlay   +29 more
doaj   +1 more source

Epidemiology and control of polioviruses in Nigeria

, 2010
Although the World Health Assembly resolved to eradicate wild poliovirus (WPV) by 2000, four countries have yet to interrupt transmission of WPVs. As of 2009, Nigeria has reported the largest burden of poliovirus of any single country for 5 of the last ...
Jenkins, Helen
core   +1 more source

PLAQUE AND GROWTH CHARACTERISTICS OF DIFFERENT POLIOVIRUSES ISOLATED FROM ACUTE FLACCID PARALYSIS IN NORTHERN NIGERIA

, 2011
Objective: To determine some virulent trait-related properties of poliovirus isolates from children with acute flaccid paralysis following vaccination with oral polio vaccine (OPV).Design: Six polioviruses earlier characterised into wild, vaccine-derived
SULE, W. F., ADU, F. D., OSEI-KWASI, M., ODOOM, J. K., OYEDELE, O. I   +4 more
core  

Poliovirus intrahost evolution is required to overcome tissue-specific innate immune responses

Nature Communications, 2017
RNA viruses, such as polioviruses, have a great evolutionary capacity and can adapt quickly during infection. Here, the authors show that poliovirus infection in mice requires adaptation to innate immune microenvironments encountered in different tissues.
Yinghong Xiao, Patrick Timothy Dolan, Elizabeth Faul Goldstein, Min Li, Mikhail Farkov, Leonid Brodsky, Raul Andino   +6 more
doaj   +1 more source

Poliovirus Excretion in Children with Primary Immunodeficiency Disorders, India

Emerging Infectious Diseases, 2017
Prolonged excretion of poliovirus can occur in immunodeficient patients who receive oral polio vaccine, which may lead to propagation of highly divergent vaccine-derived polioviruses (VDPVs), posing a concern for global polio eradication.
Madhu Chhanda Mohanty, Manisha Rajan Madkaikar, Mukesh Desai, Prasad Taur, Uma Prajwal Nalavade, Deepa Kailash Sharma, Maya Gupta, Aparna Dalvi, Snehal Shabrish, Manasi Kulkarni, Jahnavi Aluri, Jagadish Mohanrao Deshpande   +11 more
doaj   +1 more source

First case of vaccine derived poliovirus isolated from a patient with a primary immune deficiency in Sri Lanka

Sri Lankan Journal of Infectious Diseases, 2014
Persons with primary immune deficiency disorders (PID) exposed to oral polio vaccine (OPV)) are at increased risk of vaccine-associated paralytic poliomyelitis (VAPP)  and prolonged excretion of vaccine-derived polioviruses (VDPVs) VDPVs are identified ...
S Gunasena, R de Silva, D Ratnayake, C Kumarasiri, J Deshpande   +4 more
doaj   +1 more source

Neurovirulent vaccine-derived polioviruses in sewage from highly immune populations. [PDF]

, 2006
International audienceBACKGROUND: Vaccine-derived polioviruses (VDPVs) have caused poliomyelitis outbreaks in communities with sub-optimal vaccination.
Shulman, Lester M, Mendelson Ella, Swartz, Tiberio, Mendelson, Ella, Yossi Manor, Handsher Rachel, Francis Delpeyroux, Shulman Lester M., Ella Mendelson, Manor Yossi, Lester M Shulman, Sofer, Danit, Delpeyroux, Francis, Sofer Danit, Swartz Tiberio, Rachel H, Tiberio Swartz, Danit Sofer, Handsher, Rachel, Manor, Yossi, Delpeyroux Francis, Rachel Handsher, Lester M. Shulman   +22 more
core   +1 more source

Search for poliovirus carriers among people with primary immune deficiency diseases in the United States, Mexico, Brazil, and the United Kingdom

Bulletin of the World Health Organization, 2004
OBJECTIVE: To estimate the rate of long-term poliovirus excretors in people known to have B-cell immune deficiency disorders. METHODS: An active search for chronic excretors was conducted among 306 persons known to have immunoglobulin G (IgG) deficiency ...
Halsey Neal A., Pinto Jorge, Espinosa-Rosales Francisco, Faure-Fontenla María A., Silva Edson da, Khan Aamir J., Webster A.D.B., Minor Philip, Dunn Glynis, Asturias Edwin, Hussain Hamidah, Pallansch Mark A., Kew Olen M., Winkelstein Jerry, Sutter Roland   +14 more
doaj  

Is it time to switch to a formulation other than the live attenuated poliovirus vaccine to prevent poliomyelitis?

Frontiers in Public Health
The polioviruses (PVs) are mainly transmitted by direct contact with an infected person through the fecal-oral route and respiratory secretions (or more rarely via contaminated water or food) and have a primary tropism for the gut.
Christian Albert Devaux, Christian Albert Devaux, Pierre Pontarotti, Pierre Pontarotti, Anthony Levasseur, Philippe Colson, Didier Raoult   +6 more
doaj   +1 more source