Results 41 to 50 of about 3,819,008 (342)

Making tau amyloid models in vitro: a crucial and underestimated challenge

FEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

Friedrich Engels’s view on theoretical thinking: innovative application by the Communist Party of Vietnam in the reform process

Humanities & Social Sciences Communications
Marxism-Leninism has become a widespread ideological foundation that is consistently and firmly pursued by the Communist Party of Vietnam (CPV) in its leadership orientation for national development.
Nguyen Van Quang, Nguyen Hai Thanh, Nguyen Ngoc Anh, Tran Nhat Duat, Nguyen Dung Anh   +4 more
doaj   +1 more source

Intimate partner violence and its associations among HIV-infected MSM with new drug abuse in Jinan, China

BMC Public Health, 2023
Background Intimate Partner Violence (IPV) is prevalent among HIV-infected men who have sex with men (MSM), with well-established risk factors and adverse outcomes. However, there is a lack of comprehensive investigation of both upstream risk factors and
Yong Yu, Huiling Cai, Xi Chen, Fuqun Xiao, Keke Qin, Jiahong Li   +5 more
doaj   +1 more source

Justice and the Politics of Difference

The New Social Theory Reader, 1990
This book challenges the prevailing philosophical reduction of social justice to distributive justice. It critically analyzes basic concepts underlying most theories of justice, including impartiality, formal equality, and the unitary moral subjectivity.
I. Young
semanticscholar   +1 more source

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

FEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu, Huseyn Babayev, Ismail Ogulur, Sena Ardicli, Yagiz Pat, Duygu Yazici, Bingjie Zhao, Lihong Chang, Xiaoqing Liu, Paolo D'Avino, Manru Li, Ceren Biçer, Fatma Hacer Kurtoğlu Babayev, Raja Dhir, Kari C. Nadeau, Marie‐Charlotte Brüggen, Mubeccel Akdis, Cezmi A. Akdis   +17 more
wiley   +1 more source

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

FEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan, Lu Qi, Pierre Zalloua   +2 more
wiley   +1 more source

Human Security and the Special Autonomy

Bestuurskunde, 2022
Issues of human rights violations, poverty, unemployment, low HDI, low access to education, and poor health are the most important parts of the concept of human security introduced by the UNDP report 1994. These issues have not been adequately addressed
Hendy Setiawan, Khalimatus Sa’diyah
doaj   +1 more source

Functional role and folding properties of the glucan‐binding domain of oral bacterial glucansucrase

FEBS Letters, EarlyView.
The role of the glucan‐binding domain in Streptococcus sobrinus glucansucrase was examined, focusing on its impact on enzymatic activity, dextran binding, and structural stability of deletion mutants and a circularly permuted protein. Our research revealed that glucosyl transfer efficiency is linked to cooperative interdomain folding.
Hideyuki Komatsu, Takayuki Sadakane, Yudai Murata, Junichi Taira, Hiroshi Sakamoto, Takao Kodama   +5 more
wiley   +1 more source

An Overview of Post-structuralism in Comparative Analysis of Pakistan and Türkiye in Managing Refugee Crisis

Journal of Research in Social Sciences, 2022
Pakistan and Türkiye host millions of registered Afghan and Syrian refugee respectively and provide them with humanitarian aid. This study highlights the picture demonstrated to the world, made by Türkiye and Pakistan to address refugee crises. In Middle
Khushboo Fatima, Dr. Amna Mahmood, Muneeba Shahid   +2 more
doaj   +1 more source

Historical Institutionalism in comparative politics

, 1997
This article provides an overview of recent developments in historical institutionalism. First, it reviews some distinctions that are commonly drawn between the ihistoricali and the irational choicei variants of institutionalism and shows that there are ...
K. Thelen
semanticscholar   +1 more source