Results 111 to 120 of about 18,453 (257)
Fragment Edges Benefit a Common Predator of Pollinators via Bottom‐Up Effects
Integrative Zoology, EarlyView.This study investigated the hypotheses regarding the effects of habitat fragmentation on spider biomass and causing bottom‐up or top‐down effects on multi‐trophic relationships. ABSTRACT Defaunation following habitat fragmentation typically threatens predators at higher trophic levels, which further alter prey and plants via top‐down effects.
Wenlong Zhou +7 more
wiley +1 more source
Serotonin Degradation and Lipid Metabolism Regulate Human Tc2 Cell Effector Functions
Allergy, EarlyView.Human Tc2 cells exhibit a metabolically active phenotype characterized by enhanced glycolysis, mitochondrial respiration, and fatty acid uptake dependent on PPARγ. Alarmins strongly amplify IL‐5 and IL‐13 production in Tc2 cells, supporting a shared immunometabolic program across type 2 lymphocytes.
Sabrina de Souza Ferreira +13 more
wiley +1 more source
Allergy, EarlyView.ABSTRACT The skin is far from a passive shield; it functions as a dynamic “living barrier” whose structural and immunological integrity is paramount in preventing atopic dermatitis (AD) and the subsequent progression of the atopic march toward food allergy (FA).
Klaudia Ryczaj +4 more
wiley +1 more source
Allergy, EarlyView.We compared Finnish and Russian Karelian adolescents with contrasting allergy burden using integrated proteomic, metabolomic, and transcriptomic profiling. Finnish adolescents showed a broader pro‐inflammatory PBMC secretory profile consistent with a low‐grade inflammatory phenotype.
Nanna Fyhrquist +11 more
wiley +1 more source
Allergy, EarlyView.Birch pollen and PM10 are key determinants of clinical symptoms, particularly in asthma. Allergic people react stronger to the pollen collected in the highly polluted area than in the less polluted areas. When evaluating the effectiveness of allergen immunotherapy, it is essential to consider not only pollen concentrations but also levels of air ...
Maria Czarnobilska +5 more
wiley +1 more source
Archaeometry, EarlyView.ABSTRACT Lake sediments are natural archives of past environmental dynamics and how these systems have responded to past climate variability. Sediment geochemistry, governed by local geology and climate processes, is unique to each lake‐catchment and geochemical proxies must be validated for each study site.
Jalene Nalbant +6 more
wiley +1 more source
Boreas, EarlyView.Palynological records are central to the biostratigraphic subdivision of the Late Pleistocene in central Europe. Yet many interglacial and interstadial phases—such as the Eemian, Brörup and Odderade—remain only poorly constrained in time due to limited numerical dating.
Michael Hein +19 more
wiley +1 more source
Boreas, EarlyView.Land snail successions in the lower Rhône valley allow us to reconstruct the postglacial recolonization. From the Lateglacial period onwards, Mediterranean steppe communities appeared. The arrival of forest taxa was significantly delayed by aridity. The question of glacial refugia, both local and distant, primarily concerned Mediterranean species of ...
Frédéric Magnin
wiley +1 more source
MCL‐1 inhibition triggers a largely reversible cardiac stress signature in a humanised mouse model
British Journal of Pharmacology, EarlyView.Abstract Background and Purpose Myeloid cell leukaemia‐1 (MCL‐1) is an essential anti‐apoptotic protein and a promising therapeutic target in oncology. Early clinical studies of MCL‐1 inhibitors reported unexpected elevations in cardiac troponin, raising concerns about potential cardiotoxicity.
Markus B. Heckmann +7 more
wiley +1 more source
Geophysical Monograph Series, Page 263-304., 2021 Exploring the links between Large Igneous Provinces and dramatic environmental impact
An emerging consensus suggests that Large Igneous Provinces (LIPs) and Silicic LIPs (SLIPs) are a significant driver of dramatic global environmental and biological changes, including mass extinctions.
Jessica H. Whiteside +3 more
wiley +1 more source