Results 151 to 160 of about 11,077 (197)
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Food Chemistry
In this study, we fabricated and characterized nanoparticles with a core/shell structure using lecithin and poloxamer. We also evaluated their ability to load proteins. At a lecithin/poloxamer ratio of 0.2, the sizes of lecithin/P188 (low molecular weight poloxamer) and lecithin/P338 (high molecular weight poloxamer) nanoparticles were 316.1 and 280.7 ...
Jihyo, Lee, Eunhee, Yoo, Seung Jun, Choi
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In this study, we fabricated and characterized nanoparticles with a core/shell structure using lecithin and poloxamer. We also evaluated their ability to load proteins. At a lecithin/poloxamer ratio of 0.2, the sizes of lecithin/P188 (low molecular weight poloxamer) and lecithin/P338 (high molecular weight poloxamer) nanoparticles were 316.1 and 280.7 ...
Jihyo, Lee, Eunhee, Yoo, Seung Jun, Choi
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Poloxamer 188 as vehicle for injectable diazepam
Journal of Pharmaceutical Sciences, 1980The significant occurrence of thrombophlebitis in patients administered diazepam intravenously was described recently. This side effect has been attributed to the crystallization of diazepam and its subsequent precipitation upon contact with blood or intravenous fluids.
A V, Prancan +3 more
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Langmuir
Poloxamer 407 (P407) is an ABA triblock polymer widely used in therapeutic delivery due to its temperature-dependent micellization and ordering behavior. However, using P407 to deliver therapeutics across biological barriers remains difficult, as additives that enhance drug flux often hinder formulation stability and mechanical properties.
Charles T. Knisely +3 more
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Poloxamer 407 (P407) is an ABA triblock polymer widely used in therapeutic delivery due to its temperature-dependent micellization and ordering behavior. However, using P407 to deliver therapeutics across biological barriers remains difficult, as additives that enhance drug flux often hinder formulation stability and mechanical properties.
Charles T. Knisely +3 more
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Rheological properties of poloxamer vehicles
International Journal of Pharmaceutics, 1984Abstract The rheological behavior of poloxamer vehicles as a function of composition and temperature was evaluated using continuous shear methods. For poloxamer vehicles in the sol state (low concentration and temperature) a linear relationship was observed between shear rate and shear stress. For some of the vehicles, as concentration or temperature
Susan C. Miller, Bernadette R. Drabik
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Preparation of a novel poloxamer hydrogel
Journal of Applied Polymer Science, 2003AbstractPoloxamer hydrogels were prepared by photopolymerization from poloxamer macromer, which was synthesized by reaction of poloxamer 407 with acryloyl chloride. The synthesis of poloxamer macromer was confirmed using NMR and FTIR spectrometry. The gelation behavior and crystalline structure of poloxamer macromer was similar to those of poloxamer ...
HaeYong Kweon +6 more
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Thin Films of Non-Ionic Poloxamer Surfactants: Thinning and Polymerisation of Poloxamer 407
1989Thin liquid draining films of poloxamer 407 block co-polymeric surfactant solutions have been investigated using reflected laser light intensity to determine film thicknesses. Only in IM NaCl do stable thin films form. A discontinuous stepwise thinning has been found in these systems with metastable film thicknesses of, for example, 80nm and 58nm ...
A. T. Florence +2 more
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