Results 21 to 30 of about 22,356 (221)
Molecules, 2022 Polyphenolic compounds are used for treating various diseases due to their antioxidant and anticancer properties. However, utilization of hydrophobic compounds is limited due to their low bioavailability.
Katarina S. Postolović +5 more
doaj +1 more source
Effect of a poloxamer 407-based thermosensitive gel on minimization of thermal injury to diaphragm during microwave ablation of the liver. [PDF]
, 2017 AIM: To assess the insulating effect of a poloxamer 407 (P407)-based gel during microwave ablation of liver adjacent to the diaphragm. METHODS: We prepared serial dilutions of P407, and 22.5% (w/w) concentration was identified as suitable for ablation ...
Dou, Rui +7 more
core +2 more sources
Berberine Ameliorates Brain Inflammation in Poloxamer 407-Induced Hyperlipidemic Rats [PDF]
International Neurourology Journal, 2019 Purpose Hyperlipidemia, which promotes the development of atherosclerosis, ischemic stroke, and other forms of brain injury, can be induced by poloxamer-407. Berberine is a primary pharmacological active component of Coptidis Rhizoma that has a number of
Mia Kim +6 more
doaj +1 more source
Synthesis and Evaluation of Thiol-Conjugated Poloxamer and Its Pharmaceutical Applications
Pharmaceutics, 2021 The current study was designed to convert the poloxamer (PLX) into thiolated poloxamer (TPLX), followed by its physicochemical, biocompatibilities studies, and applications as a pharmaceutical excipient in the development of tacrolimus (TCM)-containing ...
Muhammad Zaman +13 more
doaj +1 more source
Calcitermin-Loaded Smart Gels Activity against Candida albicans: A Preliminary In Vitro Study
Gels, 2023 Calcitermin is an antimicrobial peptide of 15 amino acids found in human nasal fluid characterized by antifungal and antibacterial properties. Candida albicans is the most common human fungal pathogen affecting many tissues, such as vaginal mucosa.
Denise Bellotti +7 more
doaj +1 more source
Formulation of Poloxamers for Drug Delivery [PDF]
Journal of Functional Biomaterials, 2018 Poloxamers, also known as Pluronics®, are block copolymers of poly(ethylene oxide) (PEO) and poly(propylene oxide) (PPO), which have an amphiphilic character and useful association and adsorption properties emanating from this. Poloxamers find use in many applications that require solubilization or stabilization of compounds and also have notable ...
Andrew M. Bodratti +1 more
openaire +3 more sources
Supra and subgingival application of antiseptics or antibiotics during periodontal therapy
Periodontology 2000, EarlyView., 2023 Abstract Periodontal diseases (gingivitis and periodontitis) are characterized by inflammatory processes which arise as a result of disruption of the balance in the oral ecosystem. According to the current S3 level clinical practice guidelines, therapy of patients with periodontitis involves a stepwise approach that includes the control of the patient ...
Elena Figuero +5 more
wiley +1 more source
Albendazole Solid Dispersions: Influence of Dissolution Medium Composition on In Vitro Drug Release [PDF]
, 2014 The rate-limiting step to drug absorption is often dissolution from the dosage form, especially for poorly soluble com-pounds. Two possibilities for improving the dissolution of these drugs are to increase the available surface area and to im-prove their
Allemandi, Daniel Alberto +4 more
core +1 more source
International Journal of Pharmaceutics: X, 2019 The objective of this study was to evaluate in vitro and in vivo drug release from in situ forming gels prepared with poloxamer 338 (P338) and/or 407 (P407) in N-methyl-2-pyrrolidone (NMP)/water mixtures for the model compound bedaquiline fumarate salt ...
Sandy Van Hemelryck +7 more
doaj +1 more source
Chemoprevention of aberrant crypt foci in the colon of rats by dietary onion [PDF]
, 2007 Onion intake might reduce the risk of colorectal cancer, according to epidemiology. However, Femia showed in 2003 that diets with a 20% onion intake increase carcinogenesis in rats. We speculated this dose was too high.
Corpet, Denis E. +2 more
core +4 more sources