Results 11 to 20 of about 11,077 (197)
Thermogelling properties of purified poloxamer 407 [PDF]
Heliyon, 2017 Poloxamers are triblock copolymers with a center block of hydrophobic polypropylene oxide (PPO) flanked by two hydrophilic polyethyleneoxide (PEO) blocks.
Amir Fakhari +2 more
doaj +3 more sources
Hepatology, EarlyView., 2022 Hepatic APOF transcript levels correlate inversely with plasma TG and hepatic steatosis in humans. ApoF expression in mice promotes VLDL‐TG production and lipoprotein remnant clearance in mice. Abstract Background NAFLD affects nearly 25% of the global population. Cardiovascular disease (CVD) is the most common cause of death among patients with NAFLD,
Audrey Deprince +30 more
wiley +1 more source
Formulation of Poloxamers for Drug Delivery [PDF]
Journal of Functional Biomaterials, 2018 Poloxamers, also known as Pluronics®, are block copolymers of poly(ethylene oxide) (PEO) and poly(propylene oxide) (PPO), which have an amphiphilic character and useful association and adsorption properties emanating from this. Poloxamers find use in many applications that require solubilization or stabilization of compounds and also have notable ...
Andrew M. Bodratti +1 more
openaire +3 more sources
Hepatology, EarlyView., 2022 The role of SMLR1 in lipid metabolism (high fat + cholesterol diet in mice) Abstract Background and Aims The assembly and secretion of VLDL from the liver, a pathway that affects hepatic and plasma lipids, remains incompletely understood. We set out to identify players in the VLDL biogenesis pathway by identifying genes that are co‐expressed with the ...
Willemien van Zwol +22 more
wiley +1 more source
Evaluation of Ribavirin–Poloxamer Microparticles for Improved Intranasal Absorption
Pharmaceutics, 2021 Ribavirin is a water-soluble antiviral compound which, owing to its inability to cross the blood–brain barrier, has limited effectiveness in treating viruses affecting the central nervous system.
Dipy M. Vasa +4 more
doaj +1 more source
Drying of poloxamer hydrogel films [PDF]
Journal of Pharmaceutical Sciences, 2004 The drying of hydrogel films formed by Poloxamer 407 poly(ethylene oxide)-poly(propylene oxide)-poly(ethylene oxide) amphiphilic block copolymer was investigated at various air relative humidity (RH) conditions ranging from 11 to 97%. Initially, the amount of water lost increased linearly with the drying time.
Zhiyong, Gu, Paschalis, Alexandridis
openaire +2 more sources
Molecules, 2022 Polyphenolic compounds are used for treating various diseases due to their antioxidant and anticancer properties. However, utilization of hydrophobic compounds is limited due to their low bioavailability.
Katarina S. Postolović +5 more
doaj +1 more source
Berberine Ameliorates Brain Inflammation in Poloxamer 407-Induced Hyperlipidemic Rats [PDF]
International Neurourology Journal, 2019 Purpose Hyperlipidemia, which promotes the development of atherosclerosis, ischemic stroke, and other forms of brain injury, can be induced by poloxamer-407. Berberine is a primary pharmacological active component of Coptidis Rhizoma that has a number of
Mia Kim +6 more
doaj +1 more source
Synthesis and Evaluation of Thiol-Conjugated Poloxamer and Its Pharmaceutical Applications
Pharmaceutics, 2021 The current study was designed to convert the poloxamer (PLX) into thiolated poloxamer (TPLX), followed by its physicochemical, biocompatibilities studies, and applications as a pharmaceutical excipient in the development of tacrolimus (TCM)-containing ...
Muhammad Zaman +13 more
doaj +1 more source
Block copolymers as dispersants for nanomaterial added to fuel [PDF]
E3S Web of Conferences, 2023 Development and optimization of technologies using nanocomposite materials is one of important areas in modern industrial engineering. In transport industry and in fuel power engineering the use of nanoparticles can optimize fuel consumption, reduce ...
Makarova Anastasiya +5 more
doaj +1 more source