Results 21 to 30 of about 11,077 (197)
International Journal of Pharmaceutics: X, 2019 The objective of this study was to evaluate in vitro and in vivo drug release from in situ forming gels prepared with poloxamer 338 (P338) and/or 407 (P407) in N-methyl-2-pyrrolidone (NMP)/water mixtures for the model compound bedaquiline fumarate salt ...
Sandy Van Hemelryck +7 more
doaj +1 more source
Effect of Poloxamer 407 on serum VLDL, LDL and HDL levels of rabbits
National Journal of Physiology, Pharmacy and Pharmacology, 2014 Background: Poloxamer 407 is used in parenteral formulations as solubilizing and wetting agent for traditional, low-molecular-weight organic drug molecules and as stabilizing agent for proteins and polypeptide drugs.
Harish Govind Naik +5 more
doaj +1 more source
Calcitermin-Loaded Smart Gels Activity against Candida albicans: A Preliminary In Vitro Study
Gels, 2023 Calcitermin is an antimicrobial peptide of 15 amino acids found in human nasal fluid characterized by antifungal and antibacterial properties. Candida albicans is the most common human fungal pathogen affecting many tissues, such as vaginal mucosa.
Denise Bellotti +7 more
doaj +1 more source
Evaluation of 25% Poloxamer As a Slow Release Carrier for Morphine in a Rat Model
Frontiers in Veterinary Science, 2018 The objectives of this study were to evaluate poloxamer as a slow release carrier for morphine (M) and potential tissue irritation after subcutaneous poloxamer–morphine (PM) injection in a rat model.
Nurul H. Sulimai +7 more
doaj +1 more source
Supra and subgingival application of antiseptics or antibiotics during periodontal therapy
Periodontology 2000, EarlyView., 2023 Abstract Periodontal diseases (gingivitis and periodontitis) are characterized by inflammatory processes which arise as a result of disruption of the balance in the oral ecosystem. According to the current S3 level clinical practice guidelines, therapy of patients with periodontitis involves a stepwise approach that includes the control of the patient ...
Elena Figuero +5 more
wiley +1 more source
Molecules, 2017 Emodin is a component in a Chinese herb, Rheum officinale Baill, traditionally used for diabetes and anticancer. Its poor solubility is one of the major challenges to pharmaceutical scientists.
Eunmi Ban +6 more
doaj +1 more source
A Novel Chitosan Nanosponge as a Vehicle for Transepidermal Drug Delivery
Pharmaceutics, 2021 Transepidermal drug delivery achieves high drug concentrations at the action site and ensures continuous drug delivery and better patient compliance with fewer adverse effects.
Jin Sil Lee +5 more
doaj +1 more source
Pharmaceutics, 2021 Human skin is dramatically exposed to toxic pollutants such as ozone. To counteract the skin disorders induced by the air pollution, natural antioxidants such as mangiferin could be employed.
Maddalena Sguizzato +10 more
doaj +1 more source
Iraqi Journal of Pharmaceutical Sciences, 2022 This study aims to develop a thermosensitive mucoadhesive periodontal in situ gel of secnidazole for local release of drug for treatment of periodontitis, in order to increase the drug residence time and to increase patient compliance while lowering the
Dheyaa A Raheema, Hanan Jalal Kassab
doaj +1 more source
PharmaceuticalsBackground: Surfactants can be added into polymer–amorphous drug systems to further enhance solubility. However, this may cause amorphous drugs to become physically unstable, and the inherent mechanism at play here is not fully understood.
Jie Zhang +13 more
doaj +1 more source