Results 51 to 60 of about 16,153 (200)
New Biopharmaceutical Characteristics of In Situ Systems Based on Poloxamer 407
Thermosensitive systems based on poloxamer 407 are widely used in targeted drug delivery; however, the stability of the phase transition temperature remains insufficiently studied.
Elena O. Bakhrushina +8 more
doaj +1 more source
Bridging the translational gap in clinical nanomedicine: From rational design to clinical reality
Nanotechnology offers a multi‐faceted approach to modern healthcare, encompassing high‐sensitivity diagnostic imaging, innovative vaccine delivery, and targeted therapeutics. This review explores how these nanomedicine applications address critical challenges in cancer recurrence and the treatment of neurologic and respiratory diseases to combat rising
Ahmed H. Ghonaim +9 more
wiley +1 more source
Vaccine technology is still facing challenges regarding some infectious diseases, which can be addressed by innovative drug delivery systems. In particular, nanoparticle-based vaccines combined with new types of adjuvants are actively explored as a ...
Myriam Lamrayah +9 more
doaj +1 more source
High‐throughput anion‐exchange chromatography process development enables scalable purification of high‐purity recombinant adeno‐associated virus capsids. Abstract Recombinant adeno‐associated virus (rAAV) production commonly yields a high proportion of empty and partially filled capsids, necessitating downstream purification to enrich full capsids ...
Kevin Vera +8 more
wiley +1 more source
FTIR spectra of poloxamer and 1H-NMR spectra of Poloxamer 407 and HP.
(A: FTIR spectra; B: 1H-NMR spectra. a: Poloxamer 407; b: HP).
Ho Lun Wong (450683) +11 more
core +1 more source
ABSTRACT The cytoskeleton of striated muscle integrates force transmission, mechanotransduction, and sarcolemmal stability through coordinated networks of sarcomeres, costameres, and intermediate filaments. Together, these systems establish mechanical continuity between the contractile apparatus, the sarcolemma, and the extracellular matrix.
Houda Cohen +3 more
wiley +1 more source
Background Cardiomyopathy in Duchenne muscular dystrophy (DMD) is an increasing cause of death in patients. The absence of dystrophin leads to loss of membrane integrity, cell death and fibrosis in cardiac muscle.
Sali Arpana +6 more
doaj +1 more source
Microfluidic production of monodisperse food‐additive polymer capsules for biological applications
Monodisperse TGPR polymer capsules are generated via a robust microfluidic approach exploiting droplet interface transfer across the oil‒water interface. Unlike lipid vesicles, these capsules offer high thermal stability and biocompatibility. They successfully demonstrated utility as robust bioreactors for in‐capsule PCR and bacterial cultivation ...
Yuki Gondo +5 more
wiley +1 more source
Electrospraying poloxamer/(bio-)polymer blends using a needleless electrospinning machine
Electrospinning can be used to create nanofiber mats with high material purity and a large inner surface, applicable for medical or biotechnological filters, cell growth, and so on.
Daria Wehlage +3 more
core +1 more source
Potential Unlocking of Biological Activity of Caffeic Acid by Incorporation into Hydrophilic Gels
Caffeic acid, a phenolic compound with antioxidant and antimicrobial properties, shows promise in the dermatological field. The research aimed to incorporate caffeic acid into hydrophilic gels based on poloxamer 407, carbomer 980, and their mixture in ...
Monika Jokubaite, Kristina Ramanauskiene
doaj +1 more source

