Results 51 to 60 of about 16,153 (200)

New Biopharmaceutical Characteristics of In Situ Systems Based on Poloxamer 407

open access: yesGels, 2023
Thermosensitive systems based on poloxamer 407 are widely used in targeted drug delivery; however, the stability of the phase transition temperature remains insufficiently studied.
Elena O. Bakhrushina   +8 more
doaj   +1 more source

Bridging the translational gap in clinical nanomedicine: From rational design to clinical reality

open access: yesBMEMat, EarlyView.
Nanotechnology offers a multi‐faceted approach to modern healthcare, encompassing high‐sensitivity diagnostic imaging, innovative vaccine delivery, and targeted therapeutics. This review explores how these nanomedicine applications address critical challenges in cancer recurrence and the treatment of neurologic and respiratory diseases to combat rising
Ahmed H. Ghonaim   +9 more
wiley   +1 more source

Poloxamers Have Vaccine-Adjuvant Properties by Increasing Dissemination of Particulate Antigen at Distant Lymph Nodes

open access: yesMolecules, 2023
Vaccine technology is still facing challenges regarding some infectious diseases, which can be addressed by innovative drug delivery systems. In particular, nanoparticle-based vaccines combined with new types of adjuvants are actively explored as a ...
Myriam Lamrayah   +9 more
doaj   +1 more source

High‐throughput development and scale‐up of recombinant adeno‐associated virus 5 anion‐exchange chromatography for high‐purity capsid separation

open access: yesBiotechnology Progress, EarlyView.
High‐throughput anion‐exchange chromatography process development enables scalable purification of high‐purity recombinant adeno‐associated virus capsids. Abstract Recombinant adeno‐associated virus (rAAV) production commonly yields a high proportion of empty and partially filled capsids, necessitating downstream purification to enrich full capsids ...
Kevin Vera   +8 more
wiley   +1 more source

FTIR spectra of poloxamer and 1H-NMR spectra of Poloxamer 407 and HP.

open access: yes, 2013
(A: FTIR spectra; B: 1H-NMR spectra. a: Poloxamer 407; b: HP).
Ho Lun Wong (450683)   +11 more
core   +1 more source

Cytoskeleton–Membrane Uncoupling in Duchenne Muscular Dystrophy: Implications for Newborn Screening and Early Protection

open access: yesCytoskeleton, EarlyView.
ABSTRACT The cytoskeleton of striated muscle integrates force transmission, mechanotransduction, and sarcolemmal stability through coordinated networks of sarcomeres, costameres, and intermediate filaments. Together, these systems establish mechanical continuity between the contractile apparatus, the sarcolemma, and the extracellular matrix.
Houda Cohen   +3 more
wiley   +1 more source

Membrane Sealant Poloxamer P188 Protects Against Isoproterenol Induced Cardiomyopathy in Dystrophin Deficient Mice

open access: yesBMC Cardiovascular Disorders, 2011
Background Cardiomyopathy in Duchenne muscular dystrophy (DMD) is an increasing cause of death in patients. The absence of dystrophin leads to loss of membrane integrity, cell death and fibrosis in cardiac muscle.
Sali Arpana   +6 more
doaj   +1 more source

Microfluidic production of monodisperse food‐additive polymer capsules for biological applications

open access: yesDroplet, EarlyView.
Monodisperse TGPR polymer capsules are generated via a robust microfluidic approach exploiting droplet interface transfer across the oil‒water interface. Unlike lipid vesicles, these capsules offer high thermal stability and biocompatibility. They successfully demonstrated utility as robust bioreactors for in‐capsule PCR and bacterial cultivation ...
Yuki Gondo   +5 more
wiley   +1 more source

Electrospraying poloxamer/(bio-)polymer blends using a needleless electrospinning machine

open access: yes, 2018
Electrospinning can be used to create nanofiber mats with high material purity and a large inner surface, applicable for medical or biotechnological filters, cell growth, and so on.
Daria Wehlage   +3 more
core   +1 more source

Potential Unlocking of Biological Activity of Caffeic Acid by Incorporation into Hydrophilic Gels

open access: yesGels
Caffeic acid, a phenolic compound with antioxidant and antimicrobial properties, shows promise in the dermatological field. The research aimed to incorporate caffeic acid into hydrophilic gels based on poloxamer 407, carbomer 980, and their mixture in ...
Monika Jokubaite, Kristina Ramanauskiene
doaj   +1 more source

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