Results 61 to 70 of about 11,077 (197)

Systematic Review and Meta‐Analysis: Plant‐Based Therapy for Irritable Bowel Syndrome

Phytotherapy Research, EarlyView.
ABSTRACT Irritable bowel syndrome (IBS) is a common disorder of brain‐gut interaction that presents with abdominal pain, bloating associated with variable stool consistency. Many IBS patients prefer plant‐based preparations to pharmacological therapy; however, the utility of this approach is not well established.
Anselm Meyer, Jonas Auer, Lorena Cascant‐Ortolano, Niclas Schreiber, Amy Zimmermann‐Klemd, Carsten Gründemann, Philipp Busche, Jörg Schirra, Mark R. Fox   +8 more
wiley   +1 more source

Development and Characterization of Thermosensitive and Bioadhesive Ophthalmic Formulations Containing Flurbiprofen Solid Dispersions

Gels
In this study, we aimed to develop thermosensitive and bioadhesive in situ gelling systems containing solid dispersions of flurbiprofen (FB-SDs) using poloxamer 407 (P407) and 188 (P188) for ophthalmic delivery.
Pınar Adısanoğlu, Işık Özgüney
doaj   +1 more source

Peptide‐based antibacterial nanoplatforms: Design principles, stimuli‐regulated behaviors, and applications

Responsive Materials, EarlyView.
Peptide‐based antibacterial nanoplatforms, encompassing self‐assembled peptides and peptide‐engineered inorganic, polymeric, and lipid nanocarriers, are systematically reviewed. The article highlights design principles and stimuli‐responsive regulation for improving peptide stability, delivery efficiency, and antibacterial performance.
Peng Tan, Chenlong Zhou, Shuaikang Yang, Zhenduo Chen, Guanghui Zhao, Qi Tang, Haoyu Yan, Feng Li, Xi Ma   +8 more
wiley   +1 more source

Stimuli‐responsive nanostructured hydrogen sulfide donors for enhanced cancer treatments

Smart Molecules, EarlyView.
Three typical kinds of stimuli‐responsive nanostructured hydrogen sulfide (H2S) donors are reviewed. The nanostructures ensure precise delivery of H2S to the lesion site and regulate the release behavior. The H2S‐based gas therapy has been used to synergize with other cancer treatment modalities, achieving enhanced efficacy while reducing side effects.
Yuxuan Lyu, Jiaxuan Zhu, Lei Lei, Qingyang Zhong, Zhao Li, Caihong Lei, Fan Rong, Yin Wang   +7 more
wiley   +1 more source

Recent progress on the development of hydrogel‐based microneedles for transdermal drug delivery

VIEW, EarlyView.
This study provides a comprehensive and up‐to‐date analysis of recent progress in HMN technology, covering fundamental transdermal delivery mechanisms and design principles, biomaterials used in HMN fabrication, drug loading and release strategies, and emerging therapeutic applications.
Mohammad Muhtasim Ittisaf, Salman Farsi Taharat, Md. Sadek Miah, Hasan Tasnim Salehin, M. Azam Ali, Shoeb Ahmed   +5 more
wiley   +1 more source

Engineering Thermoresponsive In Situ Gels Incorporating Nutraceutical-Laden Nanostructured Lipid Carriers for Controlled Periodontal Drug Release

Gels
Periodontitis is a chronic inflammatory disease marked by the progressive destruction of periodontal tissues, where conventional therapies often fail to maintain adequate drug levels at the target site.
Rabia Ashfaq, Anita Kovács, Szilvia Berkó, Gábor Katona, Rita Ambrus, Tamás Ferenc Polgár, Mária Szécsényi, Katalin Burián, Mária Budai-Szűcs   +8 more
doaj   +1 more source

Continuous Intraperitoneal Insulin Infusion for People With Type 1 Diabetes: A Literature Review and International Position Statement

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Achieving glucose targets without hypoglycaemia is the treatment goal in type 1 diabetes. Structured education, intensified insulin injection regimens, continuous glucose monitoring, automated insulin delivery, and ongoing support from a multidisciplinary team all support people with type 1 diabetes to achieve this goal. Despite these advances,
Nick Oliver, Bernhard Gehr, Rayhan Lal, Peter R. van Dijk, Eric Renard   +4 more
wiley   +1 more source

Investigation of Rheological Characteristics of Thermosensitive Nasal In Situ Gels Based on P407 and Their Effect on Spray Pattern

Gels
This article presents the results of a study on the rheological characteristics of in situ thermosensitive nasal gels based on poloxamer 407 (P407) and their effect on spray angle.
Natalia Menshutina, Vladislav Derkach, Elizaveta Mokhova, Mariia Gordienko   +3 more
doaj   +1 more source

Erosion Potential of Commercial Fluoride‐Free Mouthwashes on Dental Hard Tissues

International Journal of Dental Hygiene, EarlyView.
ABSTRACT Purpose Mouthwashes often present acidic pH, which raises concerns about their potential contribution to erosive tooth wear. This study evaluated the erosive potential of commercial fluoride‐free mouthwashes using a screening method.
Astrid C. Valdivia‐Tapia, Adam B. Kelly, Anderson T. Hara, Jaime Aparecido Cury, Antonio Pedro Ricomini‐Filho, Frank Lippert   +5 more
wiley   +1 more source

Microneedle System Coated with Hydrogels Containing Protoporphyrin IX for Potential Application in Pharmaceutical Technology

Methods and Protocols
The article aims to outline the potential of treating malignant skin cancer with microneedles covered with polymer layers containing a photosensitizer—protoporphyrin IX disodium salt (PPIX).
Beata Czarczynska-Goslinska, Tomasz Goslinski, Agata Roszak, Anna Froelich, Piotr Szyk, Dariusz T. Mlynarczyk, Lukasz Sobotta, Irena Budnik, Oliwia Kordyl, Tomasz Osmałek   +9 more
doaj   +1 more source