Results 81 to 90 of about 11,077 (197)

Multi‐Target Anti‐Obesity Potential of Coula edulis Nut Extract in High‐Fat Diet‐Induced Obesity in Rats

Food Science &Nutrition, Volume 14, Issue 8, August 2026.
This study evaluated the multi‐target anti‐obesity effects of Coula edulis nut extract (CEE) in high‐fat diet‐induced obese Wistar rats. Following 4 weeks of obesity induction, rats received oral CEE at 1 or 2 g/kg body weight, or orlistat for 5 weeks under continued high‐fat diet or normal diet conditions.
Chidimma Emmanuel Ibeneme, Item Justin Atangwho, Godwin Eneji Egbung, Diana Ochuole Odey, Chinedum Ekeleme Martins, Uket Nta Obeten, Wilson Arong Obio, Louisiane Patrick Nangah, Emmanuel O. Ibeneme, Daniel Ejim Uti   +9 more
wiley   +1 more source

Microenvironment‐Responsive Drug Delivery Systems for Ocular Surface Diseases: Mechanisms, Applications, and Translational Challenges

Small Science, Volume 6, Issue 8, August 2026.
Microenvironment‐responsive drug delivery systems overcome ocular physiological barriers by responding to temperature, pH, ions, reactive oxygen species, and enzymes. This review bridges material design, performance evaluation, and clinical translation, offering actionable insights for treating dry eye disease, infectious keratitis, and corneal ...
Jiamin Liu, Liangbo Chen, Yao Fu, Siyi Zhang   +3 more
wiley   +1 more source

Honeydew: A Fluorescent Aptamer for Low‐Cost Azo Food Dyes

ChemBioChem, Volume 27, Issue 14, 29 July 2026.
Light‐up RNA aptamers that bind nonfluorescent dyes and conditionally activate their fluorescence are powerful tools for RNA imaging and biomolecular sensing. A barrier to widespread adoption of this technology is a reliance on bespoke dyes prepared by labor‐intensive or costly custom synthesis.
Joseph M. Heili, Paul H. Mroch, Tanner G. Hoog, Orion M. Venero, Grace M. Gustafson, Katarzyna P. Adamala, Aaron E. Engelhart   +6 more
wiley   +1 more source

Anaphylaxis Due to Poloxamer 238 [PDF]

Journal of Investigational Allergology and Clinical Immunology, 2018
A, Carbonell, A I, Escudero, J C, Miralles, A, González, C, Navarro, P, Cardona, L, Jimeno, F, Pineda   +7 more
openaire   +2 more sources

Evaluation of a Novel Cisplatin Poloxamer Gel Formulation in the Treatment of Incompletely Excised Soft-Tissue Sarcomas: 42 Dogs

Veterinary Sciences
Soft-tissue sarcomas are a heterogenous group of mesenchymal tumours that occur in dogs. Complete surgical excision is the ideal treatment for this tumour, but often, the location of the tumour makes this challenging, and the morbidity and cost of such a
Nicholas Lai, Veronika Langova, Penny Thomas, Sandra Nguyen, Johanna Todd, Joe Herbert, John Edward Blaxill   +6 more
doaj   +1 more source

Pickering Emulsion-Based Gels with Halloysite as a Stabilizer: Formulation, Mechanical Properties and In Vitro Drug Release Studies

Molecules
Lidocaine is an analgesic agent frequently incorporated in topical formulations intended for application in minor surgical procedures or relieving neuropathic pain associated with numerous conditions, including post-herpetic neuralgia or diabetic ...
Anna Froelich
doaj   +1 more source

Silver sulfadiazine nanosuspension-loaded thermosensitive hydrogel as a topical antibacterial agent

International Journal of Nanomedicine, 2018
Xiaoya Liu, Hui Gan, Chaoran Hu, Wenzhong Sun, Xiaoxia Zhu, Zhiyun Meng, Ruolan Gu, Zhuona Wu, Guifang Dou Department of Pharmaceutical Sciences, Beijing Institute of Radiation Medicine, Beijing 100850, People’s Republic of China Background ...
Liu X, Gan H, Hu C, Sun W, Zhu X, Meng Z, Gu R, Wu Z, Dou G   +8 more
doaj  

Ethyl cellulose nanoparticles as a platform to decrease ulcerogenic potential of piroxicam: formulation and in vitro/in vivo evaluation

International Journal of Nanomedicine, 2016
Salma E El-Habashy, Ahmed N Allam, Amal H El-Kamel Department of Pharmaceutics, Faculty of Pharmacy, Alexandria University, Alexandria, Egypt Abstract: Nanoparticles (NPs) have long gained significant interest for their use in various drug formulations
El-Habashy SE, Allam AN, El-Kamel AH
doaj  

SUPPOSITORIES: ASPECTS OF DOSAGE FORM MODERNIZATION

Разработка и регистрация лекарственных средств, 2019
In this material were reviewed biopharmaceutical aspects of suppositories – described the relation between rectal route of administration, bioaccessibility and principles of dosage forms formulation.
N. B. Diomina, M. N. Anurova
doaj  

Green Approach to Enhance Dissolution of Gliclazide: Thermoresponsive Solid Dispersion Based on Poloxamer 188/Propylene Glycol/Labrasol Ternary System. [PDF]

Pharmaceutics
Sherif AY, Ibrahim MA.
europepmc   +1 more source