Results 81 to 90 of about 16,153 (200)

Development of a Mucoadhesive In Situ Gelling Formulation for the Delivery of Lactobacillus gasseri into Vaginal Cavity

Pharmaceutics, 2019
Local administration of vaginal probiotics, especially lactobacilli, has been recently proposed as an effective prevention strategy against candidosis recurrences, which affect 40−50% of women.
Barbara Vigani, Angela Faccendini, Silvia Rossi, Giuseppina Sandri, Maria Cristina Bonferoni, Pietro Grisoli, Franca Ferrari   +6 more
doaj   +1 more source

Laser‐Synthesized Carbon‐Coated Elemental Bismuth Nanoparticles for Sustained Reactive Oxygen Species Generation Under Visible‐Light Irradiation

Small, EarlyView.
Femtosecond laser ablation of bismuth in acetone yields carbon‐coated nanoparticles with a metallic Bi0 core and an amorphous carbon shell. The core‐shell architecture preserves visible‐light‐driven redox activity and enables sustained hydroxyl‐radical generation.
Pavel Bezrukov, Sravan Sangeeth Surendran, Andrey Machnev, Andrei Pastukhov, Alexander Gumennik, Andrei Kabashin, Pavel Ginzburg   +6 more
wiley   +1 more source

Investigation of Rheological Characteristics of Thermosensitive Nasal In Situ Gels Based on P407 and Their Effect on Spray Pattern

Gels
This article presents the results of a study on the rheological characteristics of in situ thermosensitive nasal gels based on poloxamer 407 (P407) and their effect on spray angle.
Natalia Menshutina, Vladislav Derkach, Elizaveta Mokhova, Mariia Gordienko   +3 more
doaj   +1 more source

Stimuli‐responsive nanostructured hydrogen sulfide donors for enhanced cancer treatments

Smart Molecules, EarlyView.
Three typical kinds of stimuli‐responsive nanostructured hydrogen sulfide (H2S) donors are reviewed. The nanostructures ensure precise delivery of H2S to the lesion site and regulate the release behavior. The H2S‐based gas therapy has been used to synergize with other cancer treatment modalities, achieving enhanced efficacy while reducing side effects.
Yuxuan Lyu, Jiaxuan Zhu, Lei Lei, Qingyang Zhong, Zhao Li, Caihong Lei, Fan Rong, Yin Wang   +7 more
wiley   +1 more source

Lipid corralling and poloxamer squeeze-out in membranes

, 2004
Using x-ray scattering measurements we have quantitatively determined the effect of poloxamer 188 (P188), a polymer known to seal damaged membranes, on the structure of lipid monolayers.
Kjær, K., Majewski, Jaroslaw, Kjaer, Kristian, Lee, Ka Yee C., Lee, K.Y.C., Ege, C., Wu, G.H., Ege, Canay, Wu, Guohui, Majewski, J., Weygand, M., Weygand, Markus Jan   +11 more
core   +1 more source

Microneedle System Coated with Hydrogels Containing Protoporphyrin IX for Potential Application in Pharmaceutical Technology

Methods and Protocols
The article aims to outline the potential of treating malignant skin cancer with microneedles covered with polymer layers containing a photosensitizer—protoporphyrin IX disodium salt (PPIX).
Beata Czarczynska-Goslinska, Tomasz Goslinski, Agata Roszak, Anna Froelich, Piotr Szyk, Dariusz T. Mlynarczyk, Lukasz Sobotta, Irena Budnik, Oliwia Kordyl, Tomasz Osmałek   +9 more
doaj   +1 more source

Recent progress on the development of hydrogel‐based microneedles for transdermal drug delivery

VIEW, EarlyView.
This study provides a comprehensive and up‐to‐date analysis of recent progress in HMN technology, covering fundamental transdermal delivery mechanisms and design principles, biomaterials used in HMN fabrication, drug loading and release strategies, and emerging therapeutic applications.
Mohammad Muhtasim Ittisaf, Salman Farsi Taharat, Md. Sadek Miah, Hasan Tasnim Salehin, M. Azam Ali, Shoeb Ahmed   +5 more
wiley   +1 more source

Slow eroding biodegradable multiblock poloxamer copolymers

, 2019
Biodegradable multiblock poloxamers (BMPs) with gel duration of 8h to several weeks were prepared by varying their molecular weights from 4000 to 40 000 g mol-1.
정병문, 이민영
core   +1 more source

Rheological characterization of Poloxamer 407 nimesulide gels

, 2006
The thermal gelling property of Poloxamer 407- nimesulide gels was characterized by rheological studies. Nimesulide, a local anti-inflammatory and anesthetic drug used for the treatment of acute and chronic pain, has a short duration of action and a long-
Farah, M., Bretas, R.E.S., Marchetti, J.M., Freitas, M.N., Ricci-Júnior, E.   +4 more
core   +1 more source

Design and development of thermosensitive rectal in situ gel from Luffa acutangula fruits for the treatment of ulcerative colitis

Journal of Applied Pharmaceutical Research
Background: Luffa acutangula has good anti-inflammatory and antioxidant activity.  Ulcerative colitis has inflamed intestinal mucosal lining with frequent diarrhoea, mucosal, and bloody stools.
Swati P. Barangule, Avish D. Maru
doaj   +1 more source