Results 1 to 10 of about 25,360,752 (379)
Charge Transport in Poly(dG)–Poly(dC) and Poly(dA)–Poly(dT) DNA Polymers [PDF]
Journal of Biological Physics, 2004 We investigate the charge transport in synthetic DNA polymers built up from single types of base pairs. In the context of a polaron-like model, for which an electronic tight-binding system and bond vibrations of the double helix are coupled, we present estimates for the electron-vibration coupling strengths utilizing a quantum-chemical procedure ...
Hennig, Dirk +3 more
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Prediction of Poly(A) Sites by Poly(A) Read Mapping. [PDF]
PLoS ONE, 2017 RNA-seq reads containing part of the poly(A) tail of transcripts (denoted as poly(A) reads) provide the most direct evidence for the position of poly(A) sites in the genome.
Thomas Bonfert, Caroline C Friedel
doaj +6 more sources
Poly(Ethylene Glycol)-Poly(Lactic Acid) TLR7 Agonist as a Novel HBsAg Immune Response Stimulant
Family Medicine & Primary Care Review, 2023 Hepatitis B is caused by a hepatitis B virus infection, causing inflammation of the liver. The therapeutic approach used to help treat HBV infection has been based on re-establishing a functioning T cell response and limiting additional negative ...
BRYAN GERVAIS DE LIYIS +5 more
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RNA stabilization by a poly(A) tail 3′-end binding pocket and other modes of poly(A)-RNA interaction
Science, 2021 Poly(A) and RNA: More ways to interact One of the most conserved RNA modifications across organisms is the addition of a polyadenosine, or poly(A), tail to the 3′ end of RNA molecules.
S. Torabi +7 more
semanticscholar +1 more source
Vaccines, 2020 Infectious diseases continue to be a significant cause of morbidity and mortality, and although efficacious vaccines are available for many diseases, some parenteral vaccines elicit little or no mucosal antibodies which can be a significant problem since
Celine A. Hayden +7 more
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Polyadenylated tail length variation pattern in ultra-rapid vitrified bovine oocytes [PDF]
Veterinary World, 2016 Aim: The current study aims at investigating the polyadenylated (poly[A]) tail length of morphologically high and low competent oocytes at different developmental stages.
D. J. Dutta, Himangshu Raj, Hiramoni Dev
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High frequency, spontaneous motA mutations in Campylobacter jejuni strain 81-176. [PDF]
PLoS ONE, 2014 Campylobacter jejuni is an important cause of bacterial diarrhea worldwide. The pathogenesis of C. jejuni is poorly understood and complicated by phase variation of multiple surface structures including lipooligosaccharide, capsule, and flagellum. When C.
Krystle L Mohawk +4 more
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PLoS ONE, 2021 IntroductionWhile Campylobacter jejuni is a leading foodborne bacterial pathogen worldwide, it poses a particular risk to susceptible populations in low- and middle-income countries (LMICs).
Tegan N Clarke +5 more
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eLife, 2020 La-related protein 4 (LARP4) directly binds both poly(A) and poly(A)-binding protein (PABP). LARP4 was shown to promote poly(A) tail (PAT) lengthening and stabilization of individual mRNAs presumably by protection from deadenylation (Mattijssen et al ...
Sandy Mattijssen +4 more
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Ribosomes slide on lysine-encoding homopolymeric A stretches
eLife, 2015 Protein output from synonymous codons is thought to be equivalent if appropriate tRNAs are sufficiently abundant. Here we show that mRNAs encoding iterated lysine codons, AAA or AAG, differentially impact protein synthesis: insertion of iterated AAA ...
Kristin S Koutmou +5 more
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