Results 11 to 20 of about 24,007,230 (395)

Poly(a) selection introduces bias and undue noise in direct RNA-sequencing

open access: yesBMC Genomics, 2022
Background Genome-wide RNA-sequencing technologies are increasingly critical to a wide variety of diagnostic and research applications. RNA-seq users often first enrich for mRNA, with the most popular enrichment method being poly(A) selection.
Marcus J. Viscardi, Joshua A. Arribere
doaj   +2 more sources

Prediction of Poly(A) Sites by Poly(A) Read Mapping. [PDF]

open access: yesPLoS ONE, 2017
RNA-seq reads containing part of the poly(A) tail of transcripts (denoted as poly(A) reads) provide the most direct evidence for the position of poly(A) sites in the genome.
Thomas Bonfert, Caroline C Friedel
doaj   +5 more sources

Poly(A)-tail profiling reveals an embryonic switch in translational control

open access: yesNature, 2014
Poly(A) tails enhance the stability and translation of most eukaryotic messenger RNAs, but difficulties in globally measuring poly(A)-tail lengths have impeded greater understanding of poly(A)-tail function. Here we describe poly(A)-tail length profiling
Hazel L Sive, David P Bartel
exaly   +2 more sources

Roles of mRNA poly(A) tails in regulation of eukaryotic gene expression

open access: yesNature Reviews Molecular Cell Biology, 2021
Lori Anne Passmore, Jeff Coller
exaly   +2 more sources

Poly(Ethylene Glycol)-Poly(Lactic Acid) TLR7 Agonist as a Novel HBsAg Immune Response Stimulant

open access: yesFamily Medicine & Primary Care Review, 2023
Hepatitis B is caused by a hepatitis B virus infection, causing inflammation of the liver. The therapeutic approach used to help treat HBV infection has been based on re-establishing a functioning T cell response and limiting additional negative ...
BRYAN GERVAIS DE LIYIS   +5 more
doaj   +1 more source

RNA stabilization by a poly(A) tail 3′-end binding pocket and other modes of poly(A)-RNA interaction

open access: yesScience, 2021
Poly(A) and RNA: More ways to interact One of the most conserved RNA modifications across organisms is the addition of a polyadenosine, or poly(A), tail to the 3′ end of RNA molecules.
S. Torabi   +7 more
semanticscholar   +1 more source

Polyadenylated tail length variation pattern in ultra-rapid vitrified bovine oocytes [PDF]

open access: yesVeterinary World, 2016
Aim: The current study aims at investigating the polyadenylated (poly[A]) tail length of morphologically high and low competent oocytes at different developmental stages.
D. J. Dutta, Himangshu Raj, Hiramoni Dev
doaj   +1 more source

Co-Administration of Injected and Oral Vaccine Candidates Elicits Improved Immune Responses over Either Route Alone

open access: yesVaccines, 2020
Infectious diseases continue to be a significant cause of morbidity and mortality, and although efficacious vaccines are available for many diseases, some parenteral vaccines elicit little or no mucosal antibodies which can be a significant problem since
Celine A. Hayden   +7 more
doaj   +1 more source

Electrospinning and Post-Spun Chain Conformations of Synthetic, Hydrophobic Poly(α-amino acid)s. [PDF]

open access: yes, 2020
Electrospinning and post-spun conformations of hydrophobic poly(α-amino acid)s are described in this study. The poly(α-amino acid)s, poly(Gly), poly(L-Ala), poly(L-Val), and poly(L-Leu) were synthesized via corresponding N-carboxy-a-amino acid anhydrides.
Devarayan, Kesavan   +4 more
core   +1 more source

Home - About - Disclaimer - Privacy