Blood Biomarkers and Surface‐Enhanced Raman Spectroscopy for Gout: A Comprehensive Review
Schematic illustrating gout disease progression from asymptomatic hyperuricemia to chronic tophaceous disease, highlighting the limitations of conventional imaging and biochemical diagnostics and the potential of engineered SERS platforms for ultrasensitive blood‐based detection of urate‐related biomarkers across disease stages, with the color gradient
Isuri Perera +6 more
wiley +1 more source
Toll-like Receptor 3 as a Context-Dependent Molecular Switch in Epithelial Cancers: Balancing Cell Death and Tumor-Supportive Programs. [PDF]
Pérez-Baños A, Tittarelli A.
europepmc +1 more source
Solution‐Processed Thin‐Film Transistors With Tunable Temporal Dynamics for Neuromorphic Computing
Solution‐processed CNT and CNT/P3HT ion‐gated transistors exhibit materials‐defined synaptic timescales: fast CNT devices for high‐frequency spiking and slow hybrid devices for temporal integration. Embedding these dynamics into coupled reservoir‐computing and spiking neural network simulations reveals that a Hybrid‐Reservoir / CNT‐SNN architecture ...
Kevin Schnittker +5 more
wiley +1 more source
This work developed a smart Janus wood membrane integrating asymmetric wettability with built‐in electrical sensing for oil‐water separation. The membrane achieved > 99.5% separation efficiency and high flux by leveraging wood's natural anisotropic pore structure.
Kaiwen Chen +10 more
wiley +1 more source
Retinoic Acid-inducible Gene-I Increases Interferon-stimulated Gene 15 Expression in Human Renal Proximal Tubule Epithelial Cells. [PDF]
Tachizaki M +3 more
europepmc +1 more source
Tandem organic solar cells with optimized ternary acceptor engineering achieved a power conversion efficiency of 15.53% and enabled a high‐voltage mini‐module (Voc 6.11 V). Integration into a bias‐free PV‐EC system further demonstrated efficient solar‐to‐ammonia (STA) conversion (97% Faradaic Efficiency, 4± 2% STA efficiency), highlighting scalable ...
Seyeong Song +11 more
wiley +1 more source
Eco-friendly synthesis of an antimicrobial polymer (1,4-bis(methacryloyl)piperazine) via maghnite catalysis: <i>in vitro</i> activity and <i>in silico</i> drug-likeness. [PDF]
Derkaoui S +7 more
europepmc +1 more source
We present a novel proteolysis‐targeting chimera (PROTAC) system conjugated to lipoic acid gold nanoclusters (PLANC), designed to degrade pTau, regulate inflammatory signaling, and effectively traverse the blood‐brain barrier (BBB). PLANC degraded pTau at various phosphorylation sites, with mechanistic studies confirming proteasome‐mediated degradation
Sarah Nevins +9 more
wiley +1 more source
iFLinkC-EZ: A scalable and automatable method for the assembly of complex fusion proteins and multi-gene expression constructs based on the iFLinkC framework. [PDF]
Kemp P +7 more
europepmc +1 more source

