Results 21 to 30 of about 24,007,230 (395)

Mechanical properties and chemical stability of pivalolactone-based poly(ether ester)s [PDF]

, 1994
The processing, mechanical and chemical properties of poly(ether ester)s, prepared from pivalolactone (PVL), 1,4-butanediol (4G) and dimethyl terephthalate (DMT), were studied. The poly(ether ester)s could easily be processed by injection moulding, owing
Bantjes, A., Does, L. van der, Tijsma, E.J., Vulic, I.   +3 more
core   +7 more sources

Acoustical investigation of poly(dA).poly(dT), poly[d(A-T)].poly[d(A-T)], poly(A) . poly(U) and DNA hydration in dilute aqueous solutions [PDF]

Nucleic Acids Research, 1989
Apparent molar adiabatic compressibilities and apparent molar volumes of poly[d(A-T)].poly[d(A-T)], poly(dA).poly(dT), DNA and poly(A).poly(U) in aqueous solutions were determined at 1 degree C. The change of concentration increment of the ultrasonic velocity upon replacing counter ion Cs+ by the Mg2+ ion was also determined for these polymers.
V A, Buckin, B I, Kankiya, A P, Sarvazyan, H, Uedaira   +3 more
openaire   +2 more sources

Single molecule poly(A) tail-seq shows LARP4 opposes deadenylation throughout mRNA lifespan with most impact on short tails

eLife, 2020
La-related protein 4 (LARP4) directly binds both poly(A) and poly(A)-binding protein (PABP). LARP4 was shown to promote poly(A) tail (PAT) lengthening and stabilization of individual mRNAs presumably by protection from deadenylation (Mattijssen et al ...
Sandy Mattijssen, James R Iben, Tianwei Li, Steven L Coon, Richard J Maraia   +4 more
doaj   +1 more source

High frequency, spontaneous motA mutations in Campylobacter jejuni strain 81-176. [PDF]

PLoS ONE, 2014
Campylobacter jejuni is an important cause of bacterial diarrhea worldwide. The pathogenesis of C. jejuni is poorly understood and complicated by phase variation of multiple surface structures including lipooligosaccharide, capsule, and flagellum. When C.
Krystle L Mohawk, Frédéric Poly, Jason W Sahl, David A Rasko, Patricia Guerry   +4 more
doaj   +1 more source

A systematic review and meta-analysis of Penner serotype prevalence of Campylobacter jejuni in low- and middle-income countries.

PLoS ONE, 2021
IntroductionWhile Campylobacter jejuni is a leading foodborne bacterial pathogen worldwide, it poses a particular risk to susceptible populations in low- and middle-income countries (LMICs).
Tegan N Clarke, Megan A Schilling, Luca A Melendez, Sandra D Isidean, Chad K Porter, Frédéric M Poly   +5 more
doaj   +1 more source

Phosphodiester modifications in mRNA poly(A) tail prevent deadenylation without compromising protein expression

RNA: A publication of the RNA Society, 2020
Chemical modifications enable preparation of mRNAs with augmented stability and translational activity. In this study, we explored how chemical modifications of 5′,3′-phosphodiester bonds in the mRNA body and poly(A) tail influence the biological ...
Dominika Strzelecka, M. Śmietański, Pawel J. Sikorski, Marcin Warmiński, J. Kowalska, J. Jemielity   +5 more
semanticscholar   +1 more source

Charge transport in poly(dG)-poly(dC) and poly(dA)-poly(dT) DNA polymers [PDF]

, 2003
We investigate the charge transport in synthetic DNA polymers built up from single types of base pairs. In the context of a polaron-like model, for which an electronic tight-binding system and bond vibrations of the double helix are coupled, we present ...
Archilla, J. F. R., Hennig, D., Palmero, F., Starikov, E. B.   +3 more
core   +2 more sources

Ribosomes slide on lysine-encoding homopolymeric A stretches

eLife, 2015
Protein output from synonymous codons is thought to be equivalent if appropriate tRNAs are sufficiently abundant. Here we show that mRNAs encoding iterated lysine codons, AAA or AAG, differentially impact protein synthesis: insertion of iterated AAA ...
Kristin S Koutmou, Anthony P Schuller, Julie L Brunelle, Aditya Radhakrishnan, Sergej Djuranovic, Rachel Green   +5 more
doaj   +1 more source

Nanopore native RNA sequencing of a human poly(A) transcriptome

bioRxiv, 2018
High-throughput complementary DNA sequencing technologies have advanced our understanding of transcriptome complexity and regulation. However, these methods lose information contained in biological RNA because the copied reads are often short and ...
R. Workman, Alison D. Tang, Paul S. Tang, Miten Jain, J. R. Tyson, P. Zuzarte, Timothy Gilpatrick, Roham Razaghi, J. Quick, Norah Sadowski, N. Holmes, Jaqueline Goes de Jesus, K. Jones, T. Snutch, N. Loman, Benedict Paten, M. Loose, J. Simpson, Hugh E. Olsen, Angela N. Brooks, M. Akeson, W. Timp   +21 more
semanticscholar   +1 more source

Impact of poly(A)-tail G-content on Arabidopsis PAB binding and their role in enhancing translational efficiency

Genome Biology, 2019
Background Polyadenylation plays a key role in producing mature mRNAs in eukaryotes. It is widely believed that the poly(A)-binding proteins (PABs) uniformly bind to poly(A)-tailed mRNAs, regulating their stability and translational efficiency.
Taolan Zhao, Qing Huan, Jing Sun, Chunyan Liu, Xiuli Hou, Xiang Yu, Ian M. Silverman, Yi Zhang, Brian D. Gregory, Chun-Ming Liu, Wenfeng Qian, Xiaofeng Cao   +11 more
doaj   +1 more source