Results 241 to 250 of about 122,513 (306)

Sequence-encoded tubular architectures in disordered spider silk proteins revealed by multiscale simulations and NMR. [PDF]

PNAS Nexus
Forman CJ, Onofrei D, Stengel D, Aldana JE, Paolini C, Gianneschi NC, Holland GP.   +6 more
europepmc   +1 more source

Biocompatible Sulfobetaine Polymer‐Artemisinin Conjugates Inducing Ferroptosis in Cancer Cells: Synthesis by Mechanochemical Solid‐State Polymerization and Characterization

Macromolecular Rapid Communications, EarlyView.
The amphiphilic copolymer incorporating a hydrophobic chain conjugated with artesunate into a biocompatible sulfobetaine polymer is synthesized by solid‐state copolymerization of sulfobetaine methacrylate and methacrylamide derivative conjugating artesunate.
Naoki Doi, Yukinori Yamauchi, Yasushi Sasai, Ryosuke Nagai, Ayaka Koike, Madoka Ikawa, Toru Yoshimoto, Satoshi Yamada, Masayuki Kuzuya, Shin‐ichi Kondo   +9 more
wiley   +1 more source

MARK2 regulates C9orf72 repeat-associated non-AUG translation. [PDF]

Proc Natl Acad Sci U S A
Lu YN, Li X, Hayes L, Zhao XF, Wang J.
europepmc   +1 more source

Neurodevelopmental Disorder with Dystonia and Chorea Linked to De Novo Variants in the Splicing Regulator SRRM4

Movement Disorders, EarlyView.
Abstract Background SRRM4 is an exclusively neural‐expressed splicing‐factor gene not yet associated with a monogenic condition. Objective We sought to delineate movement disorders caused by SRRM4 variants. De novo splice‐donor‐site variants at position +2 of intron 5 of SRRM4 (c.464+2T>C, c.464+2T>A) occurred in three unrelated patients with dystonia ...
Philip Harrer, Volker Kittke, Alice Saparov, Alexej Knaus, Shimriet Zeidler, Rachel Schot, Florian Kraft, Matthias Begemann, Suzanna Koudijs, Ugo Sorrentino, Chen Zhao, Ivana Dzinovic, Martin Pavlov, Elisabeth Graf, Antonia M. Stehr, Peter M. Krawitz, Christian Wilhelm, Saskia Biskup, Fahd Alsalloum, Steffen Berweck, Juliane Winkelmann, Konrad Oexle, Ingo Kurth, G. Christoph Korenke, Michael Zech   +24 more
wiley   +1 more source

Aberrant CDK4/6-driven cell-cycle reentry drives neuronal loss and defines a therapeutic target in C9orf72 ALS/FTD. [PDF]

iScience
Lian L, Robinson H, Daniels N, Prieto GA, Poplawski GHD, Lopez-Gonzalez R.   +5 more
europepmc   +1 more source

Quantification of 10B and 11B in Biological Samples in Translational Science and Clinical Applications for Boron Neutron Capture Therapy (BNCT)

Medicinal Research Reviews, EarlyView.
ABSTRACT Boron neutron capture therapy (BNCT) is a targeted radiotherapy that exploits the selective accumulation of the 10B isotope within tumors, followed by irradiation with low‐energy neutrons to induce high linear energy transfer particles with short path lengths, resulting in localized tumor cell destruction while sparing surrounding healthy ...
Christoph Selg, Wolfgang A. G. Sauerwein, Evamarie Hey‐Hawkins   +2 more
wiley   +1 more source

Recent Developments and Applications of Capillary and Microchip Electrophoresis in Proteomics and Peptidomics (2023-2025). [PDF]

J Sep Sci
Štěpánová S, Kašička V.
europepmc   +1 more source

Solvent‐Free Fabrication of Eco‐Friendly pH‐Sensitive Smart Films From Poly(Butylene Succinate) and Red Cabbage Anthocyanin for Tracking of Chicken Breast Spoilage

Polymer Engineering &Science, EarlyView.
Smart label design. ABSTRACT The growing interest to ensure food safety requires the development of smart indicator systems that are capable of real‐time tracking of spoilage, particularly for perishable foods. Therefore, the purpose of this work is to fabricate eco‐friendly, industrially viable pH‐sensitive smart films via solvent‐free melt ...
Bedriye Ucpinar
wiley   +1 more source

An overview of recent flexible- and soft-biomaterial applications in myocardial infarction and other cardiovascular diseases. [PDF]

Mater Today Bio
Calore AR, Torresan V, Marchionni M, Gandin A, Basso E, Biasion D, Mingoni S, Molena A, Sartor G, Brusatin G, Vida V.   +10 more
europepmc   +1 more source