Results 251 to 260 of about 122,513 (306)

Curcumin induces and enhances the PARP1-mediated parthanatos in diffuse large B cell lymphoma. [PDF]

Oncol Lett
Wang Y, Qi R, Zhao X, Mei H, Qiu M, Liu F, Wang H.   +6 more
europepmc   +1 more source

Diverse reactivity of maleimides in polymer science and beyond

Polymer International, Volume 74, Issue 4, Page 296-306, April 2025.
This mini‐review provides a thorough overview of maleimide chemistry, highlighting its diverse reactivity in polymer and materials science applications. Abstract Maleimides are remarkably versatile functional groups, capable of participating in homo‐ and copolymerizations, Diels–Alder and (photo)cycloadditions, Michael additions, and other reactions ...
Bruce E Kirkpatrick, Kristi S Anseth, Tayler S Hebner   +2 more
wiley   +1 more source

Labeling of Amine-Modified Material Surfaces with PFB-Fluorescein. [PDF]

Nanotechnol Sci Appl
Jaskot K, Mielcarek AM, Popenda Ł, Kertmen A, Ivashchenko O, Grześkowiak BF, Fedoruk-Wyszomirska A, Bąkowska-Żywicka K, Tyczewska A, Barciszewski J, Perrigue PM.   +10 more
europepmc   +1 more source

Current Cell/Organoid and Animal Models for Primary Sclerosing Cholangitis

Portal Hypertension &Cirrhosis, EarlyView.
Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease with limited therapeutic options and a marked risk of progression to biliary fibrosis, cirrhosis, and malignancy. Progress in PSC research has been hindered by the lack of models that faithfully recapitulate the complex biliary microenvironment and disease heterogeneity ...
Qigu Yao, Sheng Cheng, Qiaoling Pan, Jiong Yu, Hongcui Cao   +4 more
wiley   +1 more source

MAP30, a type Ⅰ ribosome-inactivating protein, inhibits hepatocellular carcinoma by inducing apoptosis through mitochondria. [PDF]

Medicine (Baltimore)
Yang D, Peng D, Jia D, Zhou Y, Li H, Jiang Z, Meng Y.   +6 more
europepmc   +1 more source

Crop genotypic richness enhances biomass production and phosphorus acquisition in maize‐mycorrhiza symbiosis

PLANTS, PEOPLE, PLANET, EarlyView.
Our study tests how soil and plant biodiversity can enhance sustainability of crop production in Kenya. We tested whether mixtures of maize varieties performed better than monocultures and tested their response to arbuscular mycorrhizal fungi. Mycorrhizal responsiveness differed significantly by maize variety, and genetic mixtures outperformed ...
Grace Ng'endo Kanyita, Ezekiel Mugendi Njeru, Henry Birt, David Johnson   +3 more
wiley   +1 more source

Profiling heterologous 3' terminator-dependent expression variation in <i>Aspergillus oryzae</i>. [PDF]

Synth Syst Biotechnol
Zhang C, Elemosho R, Brancato ES, van der Luijt CRB, Hoof JB, Mumm NA, Mak T, Jahn LJ, Sommer MOA.   +8 more
europepmc   +1 more source

Safety, efficacy, pharmacokinetics, and mechanisms of novel 10B‐boronophenylalanine combined with a radio‐frequency quadrupole accelerator in boron neutron capture therapy: A preclinical study in head and neck squamous cell carcinoma

Precision Radiation Oncology, EarlyView.
This study demonstrates that the novel 10B‐BPA‐based BNCT system, combined with an RFQ accelerator, effectively targets head and neck squamous cell carcinoma. It induces tumor regression safely and efficiently by triggering DNA damage and activating the ROS/HIF‐1α/NF‐κB pathway, leading to caspase‐3‐mediated apoptosis.
Zhaoyuan Zhang, Junyan Li, Minhua Fan, Huafu Ouyang, Qiubo Chu, Huijie Yan, Yannan Zheng, Linxuan Huang, Gui Bao, Zhenting Ma, Shaobo Huang, Lin Li, Xiao Xu, Zhigang Liu   +13 more
wiley   +1 more source

Enzymatic and microbial routes to bioplastics: The green chemistry frontier of biopolymers. [PDF]

FEBS Open Bio
Gallo G, Piccoli E, Bombardi L, Aulitto M, Fusco S.   +4 more
europepmc   +1 more source

Impact of Stabilizing Osmolytes on the Conformational Dynamics of Human and Rat Islet Amyloid Polypeptides

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT The aggregation of human islet amyloid polypeptide (hIAPP) into cytotoxic oligomers and amyloid fibrils is a hallmark of type 2 diabetes mellitus (T2DM), leading to pancreatic β‐cell dysfunction. In contrast, rat IAPP (rIAPP) is largely non‐amyloidogenic. Osmolytes such as glucose, glycerol, and sorbitol are known to stabilize globular protein
Kiara A. Kidman, Claudio Pedrick, Cara A. Kreck, Ricardo L. Mancera   +3 more
wiley   +1 more source