TNKS1 mediates the PTEN-PI3K/AKT pathway to regulate glycolysis and proliferation in gliomas. [PDF]
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Mitochondrial acid-sensing ion channel 1a deficiency induces mitochondrial dysfunction in pulmonary arterial smooth muscle cells. [PDF]
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A Horizontally Transferred Alginate Metabolism Gene Cluster in the Human Gut Genus <i>Bacteroides</i>. [PDF]
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Genetic characterization of two novel picornaviruses from birds, white-tailed eagle (Haliaeetus albicilla) and pied avocet (Recurvirostra avosetta) in Hungary. [PDF]
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Structure and function of poly(A) binding proteins
Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression, 2004Poly (A) tails are found at the 3' ends of almost all eukaryotic mRNAs. They are bound by two different poly (A) binding proteins, PABPC in the cytoplasm and PABPN1 in the nucleus. PABPC functions in the initiation of translation and in the regulation of mRNA decay.
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