A unique poly(A) tail profile uncovers the stability and translational activation of TOP transcripts during neuronal differentiation. [PDF]
iScience, 2023 Baptissart M +6 more
europepmc +1 more source
Hydrogel‐Based Airway‐on‐Tube With Perfusable Endothelial Lumen and Outward Epithelialization
Advanced Materials, EarlyView.A hydrogel‐based airway‐on‐tube platform featuring a perfusable endothelial lumen and outward epithelialization is presented. The system supports primary human bronchial epithelial and lung microvascular endothelial coculture under air‐liquid interface conditions.
Ali Doryab +8 more
wiley +1 more source
Replication of alphaviruses requires a pseudoknot that involves the poly(A) tail. [PDF]
RNA, 2022 Olsthoorn RCL.
europepmc +1 more source
Conductive Hydrogels for Exogenous Sensing and Cell Fate Control
Advanced Materials, EarlyView.We engineer electrically conductive hydrogels by combining sulfated glycosaminoglycans with semiconducting polymers. These hydrogels bind bioactive proteins, including growth factors, whose release or retention can be modulated by low‐voltage stimulation. The hydrogels are also integrated as 3D channels in organic electrochemical transistors as part of
Teuku Fawzul Akbar +15 more
wiley +1 more source
Protocol for analyzing intact mRNA poly(A) tail length using nanopore direct RNA sequencing. [PDF]
STAR Protoc, 2023 Ogami K, Oishi Y, Hoshino SI.
europepmc +1 more source
Plasmonic Nanomachines: Creating Local Potential Gradients and Motions
Advanced Materials, EarlyView.Plasmonic nanomachines can generate optical, thermal, and chemical potential gradients to drive directional rectilinear, rotational, and twisting motions at the nanometer scale. The integration of multimodal plasmonic forces with functional materials and programmed structural distortions enables precise spatiotemporal actuation, thereby providing a ...
Yoonhee Kim +3 more
wiley +1 more source
Mechanical Stress Evolution in Polycrystalline Ge Thin Films Under MeV Ion Irradiation
Advanced Materials Interfaces, EarlyView.Irradiation of polycrystalline Ge thin films with 1.8 MeV Au ions alters residual stress through defect generation and lattice expansion. Increasing fluence drives progressive lattice disorder and eventual amorphization. Polycrystalline Ge resists amorphization longer than crystalline Ge, as grain boundaries facilitate defect diffusion, significantly ...
Karla J. Paz Corrales +10 more
wiley +1 more source
Remodeling of maternal mRNA through poly(A) tail orchestrates human oocyte-to-embryo transition. [PDF]
Nat Struct Mol Biol, 2023 Liu Y +12 more
europepmc +1 more source
3D Printed Multimaterial Microfluidic Transistors
Advanced Materials Technologies, EarlyView.We introduce a biocompatible, high resolution photopolymer resin that closely mimics the Young's Modulus (elasticity) and reversible stretchability (no hysteresis) of poly(dimethylsiloxane) (PDMS), enabling the fabrication of microfluidic transistors (i.e., microvalves capable of proportional amplification) by multimaterial stereolithography (mSLA ...
Alireza Ahmadianyazdi +7 more
wiley +1 more source
Intrinsically Unstructured Sequences in the mRNA 3' UTR Reduce the Ability of Poly(A) Tail to Enhance Translation. [PDF]
J Mol Biol, 2022 Lai WC +5 more
europepmc +1 more source