Results 181 to 190 of about 72,887 (326)

Harnessing benzamides as plant stress inhibitors, growth promoters and in management of crop resilience—A review

Plant Biology, EarlyView.
Benzamides boost crop resilience by inhibiting poly(ADP‐ribose) polymerase (PARP) to enhance stress tolerance and, through their antimicrobial, herbicidal, and insecticidal derivatives, they offer broad protection for sustainable crop improvement. Abstract Benzamides have emerged as potent stress inhibitors and growth promoters in plant biotechnology ...
M. J. Koetle, T. E. Motaung, S. O. Amoo
wiley   +1 more source

Synthesis, [18F] radiolabeling, and evaluation of poly (ADP-ribose) polymerase-1 (PARP-1) inhibitors for in vivo imaging of PARP-1 using positron emission tomography

, 2014
Dong Zhou, Wenhua Chu, Jinbin Xu, Lynne A. Jones, Xin Peng, Shihong Li, Delphine L. Chen, Robert H. Mach   +7 more
openalex   +1 more source

Incidence of myelodysplastic syndrome and acute myeloid leukemia in patients receiving poly-ADP ribose polymerase inhibitors for the treatment of solid tumors: A meta-analysis of randomized trials

, 2021
Roni Nitecki, Alexander Melamed, Allison Gockley, Jessica L. Floyd, Kate J. Krause, Robert L. Coleman, Ursula A. Matulonis, Sharon H. Giordano, Karen H. Lu, J. Alejandro Rauh‐Hain   +9 more
openalex   +2 more sources

Stellettin B renders glioblastoma vulnerable to poly (ADP-ribose) polymerase inhibitors via suppressing homology-directed repair. [PDF]

Signal Transduct Target Ther, 2023
Peng X, Wang Y, Zhang S, Tao Z, Dai Y, Claret FX, Elkabets M, Lin HW, Chen ZS, Kong D.   +9 more
europepmc   +1 more source

Hyperthermia‐induced cytotoxicity and modulation of PD‐L1 and MHC‐I expression in human non‐small cell lung cancer cell lines

Experimental Physiology, EarlyView.
Abstract Hyperthermia has recently been applied to treat human non‐small cell lung cancer (NSCLC). However, the mechanisms underlying cytotoxic sensitivity of NSCLC cells to hyperthermia are not fully understood. In this study, five NSCLC cell lines with different epidermal growth factor receptor (EGFR), Kirsten rat sarcoma and tumor protein p53 ...
Yun‐Chieh Tu, Wei‐Chen Yeh, Yi‐Wei Fang, Ko‐Hsuan Lo, Lei‐Ni Liang, Xu‐Chen Liu, Chia‐Chi Tsai, Chih‐Cheng Cheng, Meng‐Chieh Lin, Hsin‐Hsien Yu, Bor‐Chyuan Su   +10 more
wiley   +1 more source

Effects of the Poly(ADP-Ribose) Polymerase Inhibitor Olaparib in Cerulein-Induced Pancreatitis

, 2019
Akbar Ahmad, Aline Haas de Mello, Bartosz Szczęsny, Gábor Törő, Michela Marcatti, Nadiya Druzhyna, Lucas Liaudet, Stefano Tarantini, Reinaldo Salomão, Francisco García Soriano, Csaba Szabó   +10 more
openalex   +2 more sources

Across barriers: poly ADP-ribose polymerase inhibitors beyond progression in high grade serous ovarian cancer with brain metastases [PDF]

, 2020
Lawrence Kasherman, Ainhoa Madariaga, Marjan Rouzbahman, Kieran Murphy, David Shultz, Tracy Stockley, Amit M. Oza   +6 more
openalex   +1 more source

Cost-Effectiveness of Poly ADP-Ribose Polymerase Inhibitors in Cancer Treatment: A Systematic Review. [PDF]

Front Pharmacol, 2022
Chan VKY, Yang R, Wong ICK, Li X.
europepmc   +1 more source

Protein design and RNA design: Perspectives

Quantitative Biology, Volume 14, Issue 2, June 2026.
Abstract Advances in deep learning and generative modeling have transformed the landscape of protein and RNA design, enabling rapid and precise creation of novel biomolecules with tailored structures and functions. In protein design, generative deep learning frameworks now support backbone generation, sequence optimization, and joint sequence–structure
Xi Chen, Xu Dai, Peilong Lu
wiley   +1 more source

Radiation-induced neuroinflammation: a potential protective role for poly(ADP-ribose) polymerase inhibitors? [PDF]

Neurooncol Adv, 2022
Gutierrez-Quintana R, Walker DJ, Williams KJ, Forster DM, Chalmers AJ.   +4 more
europepmc   +1 more source