Results 201 to 210 of about 71,002 (280)

Different Immune Cells Modified With Chimeric Antigen Receptors Are Being Applied to Ovarian Cancer: Which Is the Most Effective?

Cancer Medicine, Volume 15, Issue 5, May 2026.
ABSTRACT Ovarian Cancer (OC), the deadliest gynecological malignancy, poses a major therapeutic challenge in advanced stages owing to its high recurrence rate and metastatic potential. In this regard, it is noteworthy that immunotherapy has recently gained significant attention in OC treatment, a phenomenon attributable to notable advances in over‐the ...
Liying Wang, Yisen Cao, Yuan Ren, Yuhang Zhang, Liang Wang   +4 more
wiley   +1 more source

Efficacy and safety of angiogenesis inhibitors combined with poly ADP ribose polymerase inhibitors in the maintenance treatment of advanced ovarian cancer: a meta-analysis. [PDF]

Front Oncol
Huang R, Ji F, Huang L, Qin Y, Liang Z, Huang M, Li C, Ban J.   +7 more
europepmc   +1 more source

Utilization of Poly(ADP-Ribose) Polymerase Inhibitors in Ovarian Cancer: A Retrospective Cohort Study of US Healthcare Claims Data. [PDF]

Adv Ther, 2022
Arend RC, O'Malley DM, Banerjee S, McLaurin K, Davidson R, Long GH.   +5 more
europepmc   +1 more source

Cryptocaryone Exhibits ROS/MAPK‐Dependent Antiproliferative and Apoptosis‐Inducing Effects on Triple‐Negative Breast Cancer Cells and Proof‐of‐Concept Breast Cancer Mouse Model

Drug Development Research, Volume 87, Issue 3, May 2026.
ABSTRACT Omics’ technologies have enabled clinicians to gain previously unprecedented insights into the molecular complexity and clinical heterogeneity of triple‐negative breast cancer (TNBC). Increasingly it is being realized that TNBC does not respond well to current targeted therapies.
Ya‐Ting Chuang, Wangta Liu, Tsu‐Ming Chien, Ammad Ahmad Farooqi, Hsun‐Shuo Chang, Jun‐Ping Shiau, Hsueh‐Wei Chang   +6 more
wiley   +1 more source

Colon-Targeted Poly(ADP-ribose) Polymerase Inhibitors Synergize Therapeutic Effects of Mesalazine Against Rat Colitis Induced by 2,4-Dinitrobenzenesulfonic Acid. [PDF]

Pharmaceutics
Kang C, Kim J, Jeong Y, Yoo JW, Jung Y.
europepmc   +1 more source

Guidance on the management of adverse reactions induced by poly(ADP-ribose) polymerase inhibitors. [PDF]

Zhejiang Da Xue Xue Bao Yi Xue Ban, 2022
Society of Obstetrics and Gynecology of Zhejiang Medical Association, Society of Urology of Zhejiang Medical Association, Committee of Breast Cancer of Zhejiang Anticancer Association, Committee of Clinical Pharmacy on Oncology of Zhejiang Anticancer Association (preparation), Committee of Urology of Zhejiang Society for Mathematical Medicine.   +4 more
europepmc   +1 more source

Potential Biological Targets of Anticancer Metal‐Based Drug Candidates: A Systematic Review

Drug Development Research, Volume 87, Issue 3, May 2026.
ABSTRACT The discovery of Cisplatin marked the beginning of the metallodrug era in oncology. Despite their clinical success, platinum‐based compounds present important limitations, including drug resistance and systemic toxicity. These challenges have stimulated interest in alternative metal complexes capable of interacting with biomolecular targets ...
Allysson L. dos S. Ferreira, Bruna B. Dantas, Jailton De Souza‐Ferrari, Edilson B. Alencar Filho   +3 more
wiley   +1 more source

Poly ADP Ribose Polymerase Inhibitors Potentiate Proton Therapy End-of-Range Effects by Accelerating Replication Forks and Promoting Transcription Conflict. [PDF]

Int J Radiat Oncol Biol Phys
Han Y, Zhou Q, Dibbs A, Chen B, Weiskittel TM, Remmes NB, Wu Z, Ebner DK, Kloeber JA, Callaghan CM, Bendel AE, Mullikin TC, Laack NN, Xu-Welliver M, Lou Z, Mutter RW.   +15 more
europepmc   +1 more source

Dietary Ergothioneine as a Novel Anti‐Aging Nutraceutical: Mechanisms, Bioavailability, and Future Perspectives

Food Frontiers, Volume 7, Issue 3, May 2026.
ABSTRACT Ergothioneine (EGT), a natural thiol derivative, has gained attention as a geroprotective nutraceutical. Preclinical research shows EGT scavenges free radicals, maintains mitochondrial integrity, slows telomere erosion, and regulates proteostasis via autophagy and senescent cell clearance.
Tian‐Tian Tian, Liang Chen, Zhen‐Zhen Dong, Chao Yang   +3 more
wiley   +1 more source

Poly (ADP-Ribose) Polymerase inhibitors (PARPi) therapy response in an acral melanoma patient with EMSY gene amplification. [PDF]

JAAD Case Rep
Nassief G, Butt OH, Zhou AY, Ansstas G.
europepmc   +1 more source