Results 261 to 270 of about 72,887 (326)

Poly(ADP-ribose) polymerases as modulators of mitochondrial activity [PDF]

, 2019
Bai, Péter, Fodor, Tamás, Liaudet, Lucas, Nagy, Lilla Nikoletta, Pacher, Pál   +4 more
core   +1 more source

Targeted Combination of Poly(ADP-ribose) Polymerase Inhibitors and Immune Checkpoint Inhibitors Lacking Evidence of Benefit: Focus in Ovarian Cancer. [PDF]

Int J Mol Sci
Bailey M, Morand S, Royfman R, Lin L, Singh A, Stanbery L, Walter A, Hamouda D, Nemunaitis J.   +8 more
europepmc   +1 more source

Poly (ADP-Ribose) Polymerase-1 (PARP-1) Inhibitors in Diabetic Retinopathy: An Attractive but Elusive Choice for Drug Development [PDF]

Etelka Pöstyéni, R. Gábriel, Andrea Kovács-Valasek   +2 more
openalex   +1 more source

Role of poly(ADP-ribosyl)ation in a 'two-hit' model of hypoxia and oxidative stress in human A549 epithelial cells in vitro [PDF]

, 2017
Erdélyi, Katalin, Pacher, Pál, Szabó, Csaba, Virág, László   +3 more
core   +1 more source

Genomics and Discrimination in New Zealand Health and Life Insurance

Journal of the Royal Society of New Zealand, Volume 56, Issue 1, February 2026.
The use of genomics offers substantial benefits to society by revolutionising approaches to healthcare and personalised medicine. It enables early detection of genetic predispositions to various diseases, allowing for proactive and tailored treatment plans, access to clinical trials, and improved health outcomes.
Andrew N. Shelling, Harry G. Fraser, Kimberley Gamet, Fay Sowerby   +3 more
wiley   +1 more source

Immunotherapy of COVID-19 with poly (ADP-ribose) polymerase inhibitors: starting with nicotinamide. [PDF]

Biosci Rep, 2020
Badawy AA.
europepmc   +1 more source

Treatment‐Related and Immune‐Related Adverse Events Associated With Immune Checkpoint Inhibitor‐Based Combination Therapies for Breast Cancer: A Systematic Review and Meta‐Analysis

Thoracic Cancer, Volume 17, Issue 3, February 2026.
This systematic review and meta‐analysis (100 trials, 9192 patients) clarifies breast cancer ICI‐based combination toxicity hierarchies. ICI‐ADC has higher grade ≥ 3 TRAEs; ICI‐mTKI has the worst irAEs, while ICI‐PARPi/HER2‐targeted combinations present the lowest risks.
Yunwei Lu, Huan Li, Ke Li, Yiting Chen, Shu Wang   +4 more
wiley   +1 more source

Regulation of R‐Loop Dynamics by Proteins and Long Noncoding RNAs: An Emerging Paradigm for Cancer Treatment

Cancer Science, Volume 117, Issue 2, Page 297-307, February 2026.
R‐loops are three‐stranded nucleic acid structures whose dysregulation leads to genomic instability and cancer progression. This review summarizes the protein and lncRNA machineries that regulate R‐loop dynamics and discusses the therapeutic potential of targeting these pathways in cancer.
Miho M. Suzuki, Keiko Shinjo, Tatsunori Nishimura, Yutaka Kondo   +3 more
wiley   +1 more source

Excitotoxicity in the lung: N-methyl-D-aspartate-induced, nitric oxide-dependent, pulmonary edema is attenuated by vasoactive intestinal peptide and by inhibitors of poly(ADP-ribose) polymerase.

, 1996
Sami I. Said, Hasan Berisha, H. Pakbaz
openalex   +2 more sources

Changes in Epithelial Ovarian Cancer Recurrence and Survival According to Treatment Paradigm Shifts

Journal of Obstetrics and Gynaecology Research, Volume 52, Issue 2, February 2026.
ABSTRACT Aim To evaluate oncologic outcomes in patients with epithelial ovarian cancer (EOC) amid evolving surgical and systemic therapy paradigms. Methods This retrospective cohort study included patients diagnosed with EOC from June 2003 to December 2020 at a single tertiary center, grouped by diagnosis period.
Jeongyun Kim, Dong Hoon Suh, Kidong Kim, Jae Hong No, Yong Beom Kim   +4 more
wiley   +1 more source