Results 121 to 130 of about 63,203 (259)

Olaparib‐associated cutaneous vasculitis in a patient with breast cancer

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Marcial Álvarez‐Salafranca, Teresa Puértolas, Adrián Diago, María Carmen Gómez‐Mateo   +3 more
wiley   +1 more source

Tumor Infiltrating Lymphocyte Therapy Combined With PD‐1/LAG‐3 Inhibition in Patients With Recurrent Platinum‐Resistant Ovarian Cancer

International Journal of Cancer, Volume 159, Issue 7, Page 1735-1749, 1 October 2026.
The detection of tumor‐infiltrating lymphocytes (TILs) is a positive prognostic factor in ovarian cancer. Moreover, TILs are significantly boosted by immunotherapy, though ovarian cancer patients have seen limited benefit from immune therapies. This study investigated the safety and feasibility of TIL therapy combined with PD‐1 and LAG‐3 inhibitors in ...
Tine J. Monberg, Cathrine L. Lorentzen, Marie C. W. Westergaard, Trine Z. Iversen, Troels H. Borch, Marco Donia, Sigrid M. Mannering, Stine E. W. Banke, Özcan Met, Inge Marie Svane   +9 more
wiley   +1 more source

Homozygous Loss of Recombination Repair Genes and Poly ADP-Ribose Polymerase Inhibitor Benefit for Patients With Ovarian Cancer. [PDF]

JCO Precis Oncol
Swisher EM, Konecny G, Cohen J, Colon-Otero G, Danziger N, Lin DI, Li G, Quintanilha JCF, Decker B, Ross JS, Gearing M, Baker K, Scott T, Poyser L, Vallejos P, Elvin JA, Graf RP.   +16 more
europepmc   +1 more source

Prostate Cancer Development, Progression, and Therapy

MedComm – Oncology, Volume 5, Issue 3, September 2026.
This review provides an integrated overview of prostate cancer development, progression, and therapy, spanning historical milestones, molecular mechanisms, advanced research models, and emerging therapeutic strategies. It highlights recent advances in precision diagnosis, lineage plasticity, therapy resistance, and next‐generation treatments for ...
Xin Jin, Zicheng Xiao, Zexian Ding, Wei Li, Ruijiang Zeng, Yujun Shuai, Weimin Ci, Dan Xia, Xu Zhang, Haojie Huang   +9 more
wiley   +1 more source

Targeting poly(ADP-ribose) polymerase in metastatic prostate cancer: current landscape and future directions. [PDF]

Curr Opin Oncol
Shi X, Rifai S, Meher Z, Hussain A.
europepmc   +1 more source

The WHO Classification of Genetic Tumour Syndromes: Considerations for Genetics

Clinical Genetics, Volume 110, Issue 3, Page 389-401, September 2026.
The WHO Classification of Tumours underpins the diagnosis of neoplastic conditions. The new WHO classification of genetic tumour syndromes (GTS) provides international standards for their diagnosis. This diagram highlights the chromosomal distribution of the genes involved in the GTS covered in this classification.
Ian A. Cree, Mark J. Arends, Joseph D. Khoury, Erika R. E. Denton, Anthony J. Gill, Alexander J. Lazar, Ian M. Frayling, Stefan M. Pfister, Mark A. Rubin, Katia R. M. Leite, Raymond Dalgleish, Elspeth A. Bruford, Sharon E. Plon, Ada Hamosh, Michael Francis Walsh, Gabrielle Goldman‐Lévy, Harshima Wijesinghe, William D. Foulkes, Dilani Lokuhetty   +18 more
wiley   +1 more source

ZIP1 Is a Critical DNA Damage‐Responsive Zinc Transporter Induced by Bleomycin via the TNFα–NF‐κB Pathway

The FASEB Journal, Volume 40, Issue 16, 31 August 2026.
The zinc transporter ZIP1 is induced promptly following treatment with the DNA damage agent bleomycin through the TNFα–NF‐κB pathway. NF‐κB accumulates in the nucleus and upregulates the transcription of SLC39A1, the coding gene for ZIP1. The increased expression of ZIP1 leads to elevated intracellular zinc levels, which, in turn, enhance the DNA ...
Zichong Li, Jiajian Yuan, Ziqi Zhang, Hong Huang, Mei Hong   +4 more
wiley   +1 more source

Synthesis of the Core Tetracycle of the Spirobiflavonoid Daphnodorin C

European Journal of Organic Chemistry, Volume 29, Issue 30, 12 August 2026.
Core spirotetracycle of daphnodorin C: Oxidative ring contraction of benzofuro[3,2‐b]chromenones affords novel 2,3′‐spirobi[benzofuran]diones, rather than the isomeric spiroketals. The first synthesis of the spirobi[benzofuran]dione core structure of the spirobiflavonoid daphnodorin C is described.
Lukas Heemann, Peter G. Jones, Thomas Lindel   +2 more
wiley   +1 more source

Exacerbated salmonellosis in poly(ADP-ribose) polymerase 14-deficient mice. [PDF]

Microbiol Spectr
Vedantham M, Polari L, Rissanen T, Pulliainen AT.   +3 more
europepmc   +1 more source

From tumor‐centric to ecosystem‐based hypotheses in brain tumor research and care

Molecular Oncology, Volume 20, Issue 8, Page 1905-1912, August 2026.
Primary brain tumors, whether in adults or children, present a major challenge because of their dramatic prognosis and the ongoing lack of efficient therapeutic approaches. In recent years, a shift has occurred from tumor‐centric concepts to a more holistic view of these tumors as dynamic ecosystems.
Julie Gavard, Flavie Bénard, Eva Billat, Margaux Le Guyon, Victoria Maltret, Laura Merlet, Chloé Astrid Walter, Tony Avril, Eric Chevet   +8 more
wiley   +1 more source