Results 171 to 180 of about 279,067 (313)

Mechanically adjustable and degradable scaffolds for the treatment of articular cartilage defects

, 2014
Articular cartilage (AC) has long been known as the tissue that “once destroyed, is not repaired”. Damage to the AC may impair joint function, leading to osteoarthritis, joint destruction, and ultimately, joint replacement.
Ching, Kuan Yong
core  

Exploring an Alternative to mRNA Vaccine Cold Chain Storage: MRNA‐Lipid Nanoparticle Stability When Dried in a Polymer Matrix

Advanced Functional Materials, EarlyView.
The nanostructure, size, and function of mRNA‐loaded lipid nanoparticles are evaluated before drying, within polymer microneedles, and after rehydration. The results reveal the polymer and LNP loadings required to recover nanostructure and preserve the delivery performance in dry‐state formulations.
Brendan P. Dyett, Shahad K. Alsaiari, John L. Daristotle, Timothy A. Forster, Alicia Lau, Dhruv Varshney, Rania Afaneh, Andrew R. Hanna, Charles Sloane, David Mankus, Haitao Yu, Jiali Zhai, DongSoo Yun, Lisa H. Tostanoski, Abigail Lytton‐Jean, Dan H. Barouch, Charlotte E. Conn, Robert Langer, Ana Jaklenec, Calum J. Drummond   +19 more
wiley   +1 more source

Further characterization of a poly(U), poly(C) ribonuclease from the insect Ceratitis capitata

, 1992
A ribonuclease from 6 day old larvae of Ceratitis capitata has been purified to homogeneity by a four step procedure. The enzyme appears as a single polypeptide chain of approx. 34 kDa.
Fragoulis, E.G., Lalioti, V.S., Sideris, D.C.   +2 more
core  

The balance of poly(U) polymerase activity ensures germline identity, survival and development in Caenorhabditis elegans.

Development, 2018
Li Y, Maine EM.
europepmc   +1 more source

Dual‐Mode Magnetic Elastomer for On‐Demand Motion and Degradation

Advanced Functional Materials, EarlyView.
A dual‐mode magnetic elastomer is introduced, enabling DC field‐driven programmable actuation and AC field‐driven magnetothermal degradation. GHz‐range magnetic fields generate ultrafast heating of magnetic nanoparticles that activates cleavage of the silicone elastomer matrix.
Jieun Han, Hyun An, Min‐Ha Oh, Yu‐Lim Lee, Woojin Jeon, Kyung‐Sub Kim, Jae‐Hwan Lee, Seungmin Kang, Yoon‐Nam Kim, Ji‐Won Kang, Daewhan Kim, Min Sang Kwon, Sang‐Koog Kim, Seung‐Kyun Kang   +13 more
wiley   +1 more source

Moving Beyond Oligoethers: Polar Side‐Chain Engineering for Aqueous Mixed Ionic–Electronic Conductors

Advanced Functional Materials, EarlyView.
We investigate how side‐chain chemistry and hydrogen bonding affect electrochemical doping in poly(propylenedioxythiophene) polymers. Replacing oligoether side chains with hydroxyl or carboxylic acid groups nearly triples electrochemical conductivity.
Joshua M. Rinehart, Anna M. Österholm, James F. Ponder Jr., Lucas Q. Flagg, Lee J. Richter, John R. Reynolds   +5 more
wiley   +1 more source

Poly(I:C) Lipoamino Bundle LNPs Induce Tumor Cytotoxicity and Immune Activation with Enhanced Efficacy by Survivin Silencing. [PDF]

Int J Mol Sci
Yazdi M, Hasheminejad Z, Hachani K, Kache J, Grau M, Wollenberg B, Bashiri Dezfouli A, Wagner E.   +7 more
europepmc   +1 more source

High‐Index, Low‐Loss Optical Material Platforms for Ultra‐Broadband Ultraviolet‐to‐Visible Achromatic Metalenses

Advanced Functional Materials, EarlyView.
An integrated material platform combining engineered SiNx thin films and printable ZrO2 nanoparticle‐embedded resin enables broadband achromatic metalenses from the ultraviolet to visible range. The demonstrated meta‐optics achieve near‐diffraction‐limited focusing with minimal chromatic aberration.
Hyunjung Kang, Dongmin Jeon, Eunji Lee, Junsuk Rho   +3 more
wiley   +1 more source

Evaluating <i>Malat1</i>-derived 3'end sequences for functional transgene expression in human cells using synthetic mRNA delivery. [PDF]

RNA Biol
Rosemann J, Jahr GT, Macho J, Haemmerle M, Gutschner T.   +4 more
europepmc   +1 more source

Binder Engineering Suppresses Jahn–Teller‐Driven Mn Dissolution and Enables High‐Loading MnO2 Cathodes for Aqueous Zn‐Ion Batteries

Advanced Functional Materials, EarlyView.
A Zn2+‐coordinated poly(vinylidene fluoride) binder is shown to suppress Jahn–Teller‐driven Mn dissolution while improving dispersion, wettability, and structural integrity in thick MnO2 cathodes. This simple binder‐engineering strategy enables high‐loading aqueous Zn‐ion batteries with enhanced areal capacity, cycling stability, and practical promise ...
Insung Jang, Geun Yoo, Geon−Hyoung An
wiley   +1 more source