Results 121 to 130 of about 104,144 (317)
A SspI PCR-RFLP detecting a silent allele at the goat CSN2 locus [PDF]
, 2005 The comparison between the cDNA sequence obtained and the published sequences of the goat CSN2 alleles showed a new single nucleotide polymorphism (SNP) (transition C-T) at the 180th nucleotide of the ninth exon.
COSENZA, GIANFRANCO +4 more
core +1 more source
Brain Pathology, EarlyView.Default mode network (DMN) consists, in part, of the frontal (FC), precuneus (PreC), and posterior cingulate cortex (PCC), which plays a critical role in episodic memory and retrieval of autobiographical memories, displays spatiotemporal differences in the onset of amyloid and hypometabolism that reflects tau neurodegeneration and loss of connectivity ...
Sylvia E. Perez +8 more
wiley +1 more source
Tissue‐specific mechanisms of alternative polyadenylation: Testis, brain, and beyond (2018 update)
Wiley Interdisciplinary Reviews - RNA, 2019 Alternative polyadenylation (APA) is how genes choose different sites for 3′ end formation for mRNAs during transcription. APA often occurs in a tissue‐ or developmental stage‐specific manner that can significantly affect gene activity by changing the ...
C. MacDonald
semanticscholar +1 more source
The regulation of Hox gene expression during animal development [PDF]
, 2013 Hox genes encode a family of transcriptional regulators that elicit distinct developmental programmes along the head-to-tail axis of animals. The specific regional functions of individual Hox genes largely reflect their restricted expression patterns ...
Alonso, Claudio R, Mallo, Moisés
core +1 more source
Diversity of U1 Small Nuclear RNAs and Diagnostic Methods for Their Mutations
Cancer Science, Volume 116, Issue 8, Page 2270-2280, August 2025.Complex interindividual U1 snRNA diversity was unveiled. Mutations in such complex loci were precisely detected with a pangenome graph reference, which enhances the possibility of the human pangenome reference in cancer genomics. ABSTRACT U1 small nuclear RNA (snRNA) mutations are recurrent non‐coding alterations found in various malignancies, yet ...
Takuma Nakashima +15 more
wiley +1 more source
Nucleic Acids Research, 2019 Cleavage factor I mammalian (CFIm) complex, composed of cleavage and polyadenylation specificity factor 5 (CPSF5) and serine/arginine-like protein CPSF6, regulates alternative polyadenylation (APA).
Sooin Jang +7 more
semanticscholar +1 more source
ELAV links paused Pol II to alternative polyadenylation in the Drosophila nervious system
, 2015 Alternative polyadenylation (APA) has been implicated in a variety of developmental and disease processes. A particularly dramatic form of APA occurs in the developing nervous system of flies and mammals, whereby various developmental genes undergo ...
Esposito, E. +8 more
core +1 more source
Preferential superficial cortical layer activation during seizure propagation
Epilepsia, Volume 66, Issue 3, Page 929-941, March 2025.Abstract Objective Focal cortical seizures travel long distances from the onset zone, but the long‐distance propagation pathways are uncertain. In vitro and in vivo imaging techniques have investigated the local spread of seizures but did not elucidate long‐distance spread. Furthermore, classical studies in slices suggested seizure spread locally along
Anastasia Brodovskaya +4 more
wiley +1 more source
APAatlas: decoding alternative polyadenylation across human tissues
Nucleic Acids Res., 2019 Alternative polyadenylation (APA) is an RNA-processing mechanism on the 3′ terminus that generates distinct isoforms of mRNAs and/or other RNA polymerase II transcripts with different 3′UTR lengths.
Wei Hong +10 more
semanticscholar +1 more source
Editorial: Alternative Polyadenylation in Development and Disease
Frontiers in Genetics, 2022 Athma A. Pai, Yang I. Li, Paolo Provero
doaj +1 more source