Results 121 to 130 of about 57,483 (236)

Characterising the Transcriptomic Response to Interferon and Infection in European Domestic Ferret Respiratory Tissues Using Long‐Read RNA Sequencing

open access: yesImmunology, Volume 177, Issue 2, Page 299-316, February 2026.
We utilised long‐read Nanopore sequencing to characterise the transcriptome of ferret cell lines stimulated with IFN‐α as well as nasal turbinates from ferrets infected with influenza A virus. We identified novel genes and isoforms and observed elongation of poly(A) tails in the ribosome and Coronavirus Disease‐19 pathways in response to IFN‐α ...
Rubaiyea Farrukee   +7 more
wiley   +1 more source

Transcriptional outputs and condensates – formation and function

open access: yesNew Phytologist, Volume 249, Issue 3, Page 1145-1154, February 2026.
Summary The dynamic spatiotemporal organization of macromolecules is key to the proper function of the cell, allowing the exquisite regulation of diverse processes from gene expression to enzymatic function. The formation of biomolecular condensates via phase separation (PS) acts as a general mechanism for selectively concentrating proteins, nucleic ...
Stephanie Hutin   +4 more
wiley   +1 more source

A distinct class of pan-cancer susceptibility genes revealed by an alternative polyadenylation transcriptome-wide association study

open access: yesNature Communications
Alternative polyadenylation plays an important role in cancer initiation and progression; however, current transcriptome-wide association studies mostly ignore alternative polyadenylation when identifying putative cancer susceptibility genes.
Hui Chen   +16 more
doaj   +1 more source

Functional characterization of NRT1/PTR FAMILY transporters: looking for a needle in a haystack

open access: yesNew Phytologist, Volume 249, Issue 3, Page 1124-1144, February 2026.
Summary NRT1/PTR FAMILY (NPF) transporters play crucial roles in plant physiology and development due to their involvement in nitrogen nutrition and their ability to transport multiple signaling molecules and metabolites. Whereas most eukaryotic and prokaryotic NPF orthologs are peptide transporters, most flowering plant NPF transport other substrates ...
Laura Morales de Los Ríos   +6 more
wiley   +1 more source

Alternative polyadenylation dysregulation contributes to the differentiation block of acute myeloid leukemia [PDF]

open access: bronze, 2021
Amanda G Davis   +12 more
openalex   +1 more source

The Response Regulator SprE (RssB) Modulates Polyadenylation and mRNA Stability inEscherichia coli

open access: green, 2009
Valerie J. Carabetta   +3 more
openalex   +1 more source

Alternative polyadenylation factors link cell cycle to migration [PDF]

open access: gold, 2018
Mithun Mitra   +11 more
openalex   +1 more source

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