Results 131 to 140 of about 62,357 (236)

Functional interaction between the ZO-1-interacting transcription factor ZONAB/DbpA and the RNA processing factor symplekin

, 2006
Epithelial tight junctions participate in the regulation of gene expression by controlling the activity of transcription factors that can interact with junctional components.
Choquet, A, Balda, MS, Hollande, F, Matter, K, Tsapara, A, Kavanagh, E, Buchert, M   +6 more
core  

Translação local de mRNAs em sindrome de Down

, 2011
Mestrado em Biologia AplicadaO Síndrome de Down (DS) é a causa genética mais frequente de atraso mental. À semelhança de outros síndromes em que ocorrem deficiências em termos de memória e aprendizagem, as anomalias em especial ao nível das espinhas ...
Rodrigues, Carina Teresa dos Santos
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Mutational effects of splicing and polyadenylation signal elements in a coupled in vitro splicing and polyadenylation system

, 1999
In the exon definition model for splicing, proposed by Berget and colleagues, the exons, denoted by splicing signals, form the units of splicing recognition.
Cooke, Charles Leo
core  

STUB1 polyadenylation signal variant AACAAA does not affect polyadenylation but decreases STUB1 translation causing SCAR16

, 2018
We present three siblings afflicted with a disease characterized by cerebellar ataxia, cerebellar atrophy, pyramidal tract damage with increased lower limb tendon reflexes, and onset of 31 to 57 years, which is not typical for a known disease ...
Temel, Sehime G., Turkgenc, Burcu, Temel, Sehime, Yakicier, Cengiz, Giray, Asli, Eker, Amber, Yakıcıer, Cengiz, Tolun, Aslihan, Giray, Aslı, Tolun, Aslıhan, Kutuk, Ozgur, Sanlidag, Burcin, Şanlıdağ, Burçin   +12 more
core   +1 more source

A distinct class of pan-cancer susceptibility genes revealed by an alternative polyadenylation transcriptome-wide association study

Nature Communications
Alternative polyadenylation plays an important role in cancer initiation and progression; however, current transcriptome-wide association studies mostly ignore alternative polyadenylation when identifying putative cancer susceptibility genes.
Hui Chen, Zeyang Wang, Lihai Gong, Qixuan Wang, Wenyan Chen, Jia Wang, Xuelian Ma, Ruofan Ding, Xing Li, Xudong Zou, Mireya Plass, Cheng Lian, Ting Ni, Gong-Hong Wei, Wei Li, Lin Deng, Lei Li   +16 more
doaj   +1 more source

Multiple mechanisms of polyadenylation site choice in male germ cells

, 2007
Polyadenylation, the process involved in the formation of the poly(A) tail at the 3¡¬ end of eukaryotic messenger RNAs (mRNAs), has been traditionally described as a two step process.
McMahon, K. Wyatt
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Alternative Polyadenylation in Sarcocystis neurona

, 2018
This project studied the occurrence of alternative polyadenylation during the growth of Sarcocystis neurona. S. neurona is an obligate intracellular parasite that causes equine protozoal myeloencephalitis.
Stevens, Ashley
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Cytoplasmic polyadenylation in development and beyond

, 2009
Maternal mRNA translation is regulated in large part by cytoplasmic polyadenylation. This process, which occurs in both vertebrates and invertebrates, is essential for meiosis and body patterning.
Richter, Joel D.
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Regulatory Mechanisms of Intronic Polyadenylation [PDF]

Eukaryotic gene expression involves several processes, including transcription, pre-mRNA processing, mRNA export, translation, and ultimately, mRNA decay.
Soles, Lindsey
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Domains of CstF-64 and their functions in polyadenylation

, 2007
Polyadenylation, a critical process for expression of most eukaryotic genes, requires multiple protein factors and pre-mRNA elements. However, the essential nature of polyadenylation proteins precludes in vivo determination of their precise functions. We
Hockert, John Andrew
core