An essential role for polyamines in tumor metastases [PDF]
Prasad S. Sunkara +2 more
openalex +1 more source
Lifespan‐Extending Endogenous Metabolites
Endogenous metabolites act as mediators of longevity by modulating conserved cellular pathways. We summarize mechanistic evidence linking specific metabolites to lifespan and healthspan benefits across model systems, with discussion of clinical evidence, translational opportunities, and remaining knowledge gaps.
Yizhou Jiang, Jing‐Dong J. Han
wiley +1 more source
Opposite effects of spermidine and GC7 in cell culture are dictated by distinct molecular targets. [PDF]
Tahara T +8 more
europepmc +1 more source
Root cell wall plasticity in iron homeostasis: an overlooked frontier in plant nutrition
Summary Iron (Fe) is an essential micronutrient for plant growth and development, yet its availability in soils is often limited or excessive, leading to widespread Fe deficiency or toxicity that constrains crop productivity. While Fe uptake, transport, and signaling pathways have been well characterized, the role of the root cell wall as a dynamic ...
Poonam Kanwar, Petra Bauer
wiley +1 more source
Profiling polyamine-protein interactions in live cells through photoaffinity labeling. [PDF]
Zakrzewski M +8 more
europepmc +1 more source
Purification of Polyamine Oxidase from Diabetic Type-I Females and Studies of the Inhibitory Effect of some Thiourea Compounds on its Activity [PDF]
Nashwan I. Abo +2 more
openalex +1 more source
Membranaktive Peptide (MAPs) wie zellpenetrierende Peptide (CPPs) und antimikrobielle Peptide (AMPs) können Lipidmembranen durchdringen und Membranporen bilden. Die Kombination aus einem Farbstoff‐Efflux‐Assay und einem supramolekularen Tandem‐Membran‐Assay in einem Zweikanalformat ermöglicht eine fortgeschrittene mechanistische Charakterisierung und ...
Mohammad A. Alnajjar +8 more
wiley +1 more source
Identification and Verification of Biomarkers Related to Polyamine Metabolism in Diabetic Nephropathy. [PDF]
Zhou S +7 more
europepmc +1 more source
Membrane‐active peptides (MAPs) such as cell‐penetrating peptides (CPPs) and antimicrobial peptides (AMPs) can translocate across lipid membranes and create membrane pores. The combination of a dye efflux and a supramolecular tandem membrane assay in a dual‐channel format enables an advanced mechanistic characterization and an exploration of the ...
Mohammad A. Alnajjar +8 more
wiley +1 more source
Integrated spatial metabolomics and transcriptomics reveal the molecular landscape of papillary thyroid cancer and its lymph node metastasis. [PDF]
Li K +9 more
europepmc +1 more source

