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Polycystic kidney disease [PDF]

, 2017
Policistična je bolest bubrega genetski poremećaj kod kojeg se u bubrezima razvijaju i rastu ciste. Zbog cistama uvećanih bubrega, onemogućena je njihova odgovarajuća funkcija što u konačnici dovodi do zatajenja bubrega, a samim time i do potrebe za ...
Lelas, Judita
core   +1 more source

Case Report: Autosomal dominant polycystic kidney disease and Wilms’ tumor in infancy and childhood

Frontiers in Pediatrics
BackgroundAutosomal dominant polycystic kidney disease (ADPKD) is rare but one of the most common inherited kidney diseases. Normal kidney function is maintained until adulthood in most patients.
Doviltyte Zina, Doviltyte Zina, Kiudeliene Rosita, Kiudeliene Rosita, Zviniene Kristina, Zviniene Kristina, Rutkauskiene Giedre, Rutkauskiene Giedre, Masalskiene Jurate, Masalskiene Jurate   +9 more
doaj   +1 more source

The Bile Acid Signaling Axis: Deciphering the Roles of FXR and TGR5 in Hepatic Steatosis, Fibrosis, and Cancer

Pharmacology Research &Perspectives, Volume 14, Issue 5, October 2026.
ABSTRACT Bile acids (BAs) serve not only as emulsifiers for lipid digestion but also as essential signaling molecules, governing various physiological and pathological processes through their interaction with the farnesoid X receptor (FXR) and the takeda G protein‐coupled receptor 5 (TGR5).
Jie Liu, Kui Sun, Hongmei Liu, Meiyang Zhu, Chunmeng Li, Yuqi He, Lin Qin   +6 more
wiley   +1 more source

Autosomal-dominant polycystic kidney disease (ADPKD): Executive summary from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference

, 2015
Autosomal-dominant polycystic kidney disease (ADPKD) affects up to 12 million individuals and is the fourth most common cause for renal replacement therapy worldwide. There have been many recent advances in the understanding of its molecular genetics and
Torres, Vicente E., Walz, Gerd, Steinman, Theodore I., Perrone, Ronald D., Pirson, Yves, Emma, Francesco, Ecder, Tevfik, Mei, Changlin, Sandford, Richard, Harr, Nicole, Hogan, Marie C., Cowley, Benjamin, Onuchic, Luiz F., Obrador, Gregorio T., Eckardt, Kai Uwe, Mrug, Michal, Bichet, Daniel G., Martin, Rodolfo S., Jha, Vivek, Ahn, Curie, Pavia, Luisa Sternfeld, Flamion, Bruno, Aussilhou, Beatrice, Budde, Klemens, Lagrafeuil, Corinne, Winston, Kaori Yamane, Bergmann, Carsten, Watnick, Terry, Dell, Katherine M., Serra, Andreas L., Harris, Peter C., Férec, Claude, Winearls, Christopher G., Higashihara, Eiji, Galletti, Flavia, Rangan, Gopala K., Korst, Uwe, Torra, Roser, Ong, Albert C.M., Bae, Kyongtae T., Gitomer, Bernice, Devuyst, Olivier, Schrier, Robert W., Drenth, Joost P.H., Grantham, Jared J., De Coninck, Brenda, Alam, Ahsan, Strandgaard, Svend, Bennett, William M., Chapman, Arlene B., Horie, Shigeo, Chauveau, Dominique, Odland, Dwight, Hodouchi, Eiko, Gansevoort, Ron T., Harris, Tess, Pei, York, Wheeler, David C., Kasiske, Bertram L.   +58 more
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Prenatal exome sequencing of fetuses with central nervous system anomalies based on prenatal ultrasound and magnetic resonance imaging diagnosis: A retrospective cohort study with a systematic review and meta‐analysis

Acta Obstetricia et Gynecologica Scandinavica, Volume 105, Issue 10, Page 1950-1964, October 2026.
Prenatal exome sequencing significantly improves diagnostic yield over chromosomal microarray analysis for fetal CNS abnormalities, with a diagnostic yield of 16% in our cohort and 27% in the meta‐analysis. Diagnostic yields vary across different phenotypes. Abstract Introduction Fetal central nervous system (CNS) abnormalities have diverse etiologies,
Jia Yao, Yan Wang, Gang Li, Zhitao Zhang, Yuan Lv, Lizhu Chen   +5 more
wiley   +1 more source

A Hypertensive Patient With Polycystic Horseshoe Kidney

Turkish Journal of Nephrology, 2019
Adult polycystic kidney disease is transmitted in autosomal dominant pattern with a reported incidence of 1 in 1000 to 1 in 5000 cases. Horseshoe kidney is a renal fusion anomaly with an incidence of 1 in 400 to 1 in 1800 live births.
Alper KIRKPANTUR, Bülent ALTUN, Mahmut İlker YILMAZ, Müjdat YENİCESU   +3 more
doaj  

Serum Copeptin Rises After Tolvaptan for Hyponatraemia, but Does Not Predict Risk of Rapid Sodium Rise: Pre‐Specified Secondary Analysis of the TVFR Trial

Clinical Endocrinology, Volume 105, Issue 4, Page 514-518, October 2026.
ABSTRACT Objective Hyponatraemia is a common electrolyte disorder often driven by excess arginine vasopressin (AVP). Copeptin is a stable surrogate marker co‐secreted with AVP. It is unclear whether treatment of hyponatraemia with tolvaptan, an AVP‐V2 receptor antagonist, impacts copeptin.
Annabelle M. Warren, Kay Weng Choy, Rudolf Hoermann, Nicholas Russell, Mathis Grossmann   +4 more
wiley   +1 more source

Management of Rapidly Progressive Autosomal Dominant Polycystic Kidney Disease

Turkish Journal of Nephrology
Autosomal dominant polycystic kidney disease (ADPKD) is the most common inherited kidney disease. In this disease, multiple cysts develop and grow over time in both kidneys.
İsmail Koçyiğit, Emre Aydın, Özgür Akın Oto, Kadir Gökhan Atılgan, Tevfik Ecder   +4 more
doaj   +1 more source

IMPROVE 2025: The 3rd International Meeting on Pathway‐Related Obesity: Vision & Evidence

Clinical Obesity, Volume 16, Issue 5, October 2026.
ABSTRACT An international cohort of 161 clinicians and researchers from 19 countries attended the 3rd International Meeting on Pathway‐Related Obesity: Vision & Evidence (IMPROVE) in Prague, Czech Republic, on 2–4 July 2025. The aims of the meeting were to advance understanding of hyperphagia and obesity caused by defects in the melanocortin‐4 receptor
Jesús Argente, Erica L. T. van den Akker, Metin Cetiner, Karine Clément, Elizabeth Forsythe, Alastair Garfield, Peter Kühnen, Gabriel Ángel Martos‐Moreno, David Meeker, Hermann L. Müller, Hanneke M. van Santen, Julia von Schnurbein, Bérénice Segrestin, Tomohiro Tanaka, Manuel Tena‐Sempere, Martin Wabitsch, Stefanie Zorn, I. Sadaf Farooqi   +17 more
wiley   +1 more source

Five‐Year Outcomes and Clinicopathological Correlations of Kidney Transplants From Deceased Donors With Diabetes

Clinical Transplantation, Volume 40, Issue 10, October 2026.
ABSTRACT Background Kidneys from deceased donors with diabetes mellitus are refused because diabetes is considered a marker of lower organ quality. We evaluated 5‐year outcomes according to donor‐recipient diabetes status and, secondarily, the prognostic value of pre‐implantation histopathological findings among accepted diabetic donor kidneys ...
Marina Colella‐Santos, Pedro Henrique Pepato, Henrique Machado de Sousa Proença, Luiz Antonio Ribeiro de Moura, José Medina‐Pestana, Renato Demarchi Foresto, Lúcio Requião‐Moura   +6 more
wiley   +1 more source