Results 141 to 150 of about 46,408 (230)

Amino acid homeostasis in the kidney: Physiological roles and pathological dysregulation

open access: yesPhysiological Reports, Volume 14, Issue 15, August 2026.
Abstract Amino acids are fundamental to life as protein building blocks and key regulators of metabolism and signaling. The kidney plays a critical, yet underappreciated, role in amino acid homeostasis through three interconnected pillars: selective glomerular filtration, efficient tubular reabsorption, and metabolic processing, which includes de novo ...
Shuo Liu   +3 more
wiley   +1 more source

Epithelial cell expansion drives cyst progression in genetic models of autosomal recessive polycystic kidney disease. [PDF]

open access: yesiScience
Liu S   +12 more
europepmc   +1 more source

Intermittent exogenous ketosis increases erythropoietin in healthy adults: A randomized, placebo‐controlled study with preliminary sex‐specific observations

open access: yesPhysiological Reports, Volume 14, Issue 15, August 2026.
Intermittent exogenous ketosis stimulates erythropoietin, with greater EPO response and elevated ferritin in females but no significant changes in circulating hemoglobin or red blood cell count at 2 weeks. Abstract Exogenous ketosis may stimulate erythropoietin (EPO), yet its impact on erythropoiesis, iron metabolism, and potential sex‐specific ...
Henrik Holm Thomsen   +3 more
wiley   +1 more source

Centriolar Protein POC5 Regulates Human Adipogenesis and Cellular Senescence: Insights From a Novel Metabolic Ciliopathy

open access: yesThe FASEB Journal, Volume 40, Issue 14, 31 July 2026.
The identification of a patient carrying a novel homozygous p.(Gln206Ter) POC5 variant revealed a metabolic phenotype associated with POC5 deficiency. POC5 deficiency disrupts centriolar architecture and ciliary organization, leading to impaired proliferation, premature cellular senescence, and reduced insulin signaling.
Valeria Pistorio   +10 more
wiley   +1 more source

The Ion channel, CFTR, assembles with HIPPO pathway proteins TAZ and YAP in polycystic kidney disease. [PDF]

open access: yesJ Biol Chem
Sharma A   +6 more
europepmc   +1 more source

Cervical Artery Dissection in Autosomal Dominant Polycystic Kidney Disease. [PDF]

open access: yesMedicina (Kaunas)
Liu A   +4 more
europepmc   +1 more source

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