Results 141 to 150 of about 98,685 (336)

Estimating the association and timing of occurrence between obesity and related comorbidity outcomes in a real‐world setting: A cohort study in the United States

Clinical Obesity, EarlyView.
Estimating the Association and Timing of Occurrence between Obesity and Related Comorbidity Outcomes in a Real‐World Setting: A Cohort Study in the United States. An observational, retrospective cohort study of adults with available body mass index (BMI) data during the period 2010–2019 in a large United States claims‐linked electronic health records ...
Firas Dabbous, Jigish Bhavsar, Jayashri Desai, Anthony Fabricatore, Bríain Ó. Hartaigh, Wojciech Michalak, Sariya Udayachalerm, Cynthia Saiontz‐Martinez, Zhenxiang Zhao, Fatima Cody Stanford   +9 more
wiley   +1 more source

Autopsy Report with Clinical and Pathophysiologic Discussion of Autosomal Dominant Adult Polycystic Kidney Disease

Case Reports in Urology, 2014
The average weight of a kidney is approximately 135 gm, measuring on average 10 × 6 × 4 cm. In hereditary conditions, autosomal dominant and autosomal recessive polycystic kidney disease, the shape, size, and the weight can be significantly abnormal ...
Anup Hazra, Richard Siderits, Cheryl Rimmer, Noah Rolleri   +3 more
doaj   +1 more source

Should a paediatrician perform abdominal ultrasonography inchildren of parents with polycystic kidney disease?

Pediatria i Medycyna Rodzinna, 2016
Autosomal dominant polycystic kidney disease produces symptoms mainly in adulthood. Renal cysts and/or elevated blood pressure can be the first signs of the disease in children.
Krzysztof Wróblewski, Katarzyna Młudzik, Susan Afshari, Piotr Grzelak, Marcin Tkaczyk   +4 more
doaj   +1 more source

Lactate and Lactylation in AKI‐to‐CKD: Epigenetic Regulation and Therapeutic Opportunities

Cell Proliferation, EarlyView.
ABSTRACT Lactate is not only a byproduct of glycolysis, but is also considered an energy source, gluconeogenic precursor, signalling molecule and protein modifier during the process of cellular metabolism. The discovery of lactylation reveals the multifaceted functions of lactate in cellular metabolism and opens new avenues for lactate‐related research.
Yi Hou, Dongwei Liu, Zuishuang Guo, Cien Wei, Fengyu Cao, Yue Xu, Qi Feng, Fengxun Liu   +7 more
wiley   +1 more source

The pathogenesis of polycystic kidney disease.

Histology and histopathology, 1995
Polycystic kidney disease (PKD) is a genetic or acquired disorder characterized by progressive distention of multiple tubular segments and manifested by fluid accumulation, growth of non-neoplastic epithelial cells and remodeling of the extracellular matrix resulting ultimately in some degree of renal functional impairment, with the potential for ...
Carone, F.A., Bacallao, R., Kanwar, Y.S.
openaire   +2 more sources

Polycystic kidney and Down Syndrome

Journal of Research in Medical Sciences, 2006
Kidney disease is not a common complication in Down Syndrome (DS). A variety of renal and urologic problems have been described in these patients and some develop renal failure. Coincidence of polycystic kidney disease and DS is a rare entity.
Azar Nickavar
doaj  

A Classification-Based Adaptive Segmentation Pipeline: Feasibility Study Using Polycystic Liver Disease and Metastases from Colorectal Cancer CT Images [PDF]

Automated segmentation tools often encounter accuracy and adaptability issues when applied to images of different pathology. The purpose of this study is to explore the feasibility of building a workflow to efficiently route images to specifically trained segmentation models.
arxiv   +1 more source

Stem cells and fluid flow drive cyst formation in an invertebrate excretory organ.

, 2015
Cystic kidney diseases (CKDs) affect millions of people worldwide. The defining pathological features are fluid-filled cysts developing from nephric tubules due to defective flow sensing, cell proliferation and differentiation.
Alexander, R., Alvarado, A., Lakshmanaperumal, N., McClain, M., McKinney, S., Rink, J., Vu, H.   +6 more
core   +1 more source

Developments in albuminuria testing: A key biomarker for detection, prognosis and surveillance of kidney and cardiovascular disease—A practical update for clinicians

Diabetes, Obesity and Metabolism, EarlyView.
Abstract Albuminuria, the abnormal presence of albumin in urine, is a key marker of kidney damage and a strong predictor of kidney and cardiovascular outcomes. Its clinical significance has evolved from early historical observations to its current role in chronic kidney disease (CKD) detection, risk stratification and treatment monitoring.
Jelle M. Beernink, Dominique van Mil, Gozewijn D. Laverman, Hiddo J. L. Heerspink, Ron T. Gansevoort   +4 more
wiley   +1 more source

Case Report: Autosomal dominant polycystic kidney disease and Wilms’ tumor in infancy and childhood

Frontiers in Pediatrics
BackgroundAutosomal dominant polycystic kidney disease (ADPKD) is rare but one of the most common inherited kidney diseases. Normal kidney function is maintained until adulthood in most patients.
Doviltyte Zina, Doviltyte Zina, Kiudeliene Rosita, Kiudeliene Rosita, Zviniene Kristina, Zviniene Kristina, Rutkauskiene Giedre, Rutkauskiene Giedre, Masalskiene Jurate, Masalskiene Jurate   +9 more
doaj   +1 more source