Results 141 to 150 of about 462,629 (365)

Diagnostic Yield and Clinical Impact of a Small Genetic Panel for Kidney Disease: A Multicenter, Retrospective European Study

Clinical Genetics, EarlyView.
In a multicenter study of 692 patients with kidney disease, a 44‐gene panel achieved a 36% diagnostic yield. The 36% yield was not significantly lower than with larger panels or whole‐exome sequencing. A post hoc machine‐learning model identified key predictors to stratify patients into four risk bins (11%–74% yield), enabling more cost‐effective ...
Silvia Giovanella, Antonio Miguel Poyatos‐Andújar, Maria Mar Aguila Garcia, Almudena Avila‐Fernandez, Ana Bustamante‐Aragonés, Carmen Ayuso, Antonio Percesepe, Davide Martorana, Maria Ferri, Alessandra Terracciano, Laura Massella, Johanna Chester, Francesca Testa, Giulia Ligabue, Marco Ferrarini, Dino Gibertoni, Gaetano Alfano, Elena Tenedini, Lucia Artuso, Marco Marino, Olga Calabrese, Enrico Tagliafico, Riccardo Magistroni   +22 more
wiley   +1 more source

Rationale and design of the RESOLVE trial: lanreotide as a volume reducing treatment for polycystic livers in patients with autosomal dominant polycystic kidney disease

BMC Nephrology, 2012
Background A large proportion of patients with autosomal dominant polycystic kidney disease (ADPKD) suffers from polycystic liver disease. Symptoms arise when liver volume increases.
Gevers Tom JG, Chrispijn Melissa, Wetzels Jack FM, Drenth Joost PH   +3 more
doaj   +1 more source

Discussion on Polycystic Disease of the Kidneys [PDF]

, 1924
Graham J. Forbes
openalex   +1 more source

Early and Severe Polycystic Kidney Disease and Related Ciliopathies: An Emerging Field of Interest

Nephron, 2018
Early and severe forms of polycystic kidney disease (PKD) do already manifest during childhood or adolescence. They are characterized by enlarged kidneys and diminished renal function that prenatally may result in Potter’s oligohydramnios sequence ...
C. Bergmann
semanticscholar   +1 more source

Effect of glucagon‐like peptide 1 receptor agonists on systolic blood pressure in patients with obesity, with or without diabetes: A systematic review and network meta‐analysis

Clinical Obesity, EarlyView.
Summary The effect of glucagon‐like peptide 1 receptor agonists (GLP‐1RAs) on systolic blood pressure (SBP) in patients with obesity with or without diabetes remains unclear. The aim was to compare the effect of different drug–dose combinations of GLP‐1RAs on SBP.
Abraish Ali, Asad Ali Siddiqui, Muhammad Shariq Usman, Izza Shahid, Muhammad Shahzeb Khan, Prinka Perswani   +5 more
wiley   +1 more source

Glomerular Basement Membrane Protein Expression and the Diagnosis and Prognosis of Autosomal Dominant Alport Syndrome

Kidney Medicine, 2019
Alport syndrome is a hereditary glomerular nephritis associated with hearing loss and eye abnormalities and is classified as X-linked Alport syndrome, autosomal recessive Alport syndrome, and autosomal dominant Alport syndrome.
Taro Akihisa, Masayo Sato, Yoshie Wakayama, Sekiko Taneda, Shigeru Horita, Orie Hirose, Shiho Makabe, Hiroshi Kataoka, Takayasu Mori, Eisei Sohara, Shinichi Uchida, Kosaku Nitta, Toshio Mochizuki   +12 more
doaj  

Our organ donation experience in a braindead polycystic kidney disease patient: Case report

Van Tıp Dergisi, 2018
Polycystic kidney disease is an otosomal dominant hereditary disorder which can progress to end stage kidney failure. In this disease, the cysts in distinct sizes and distinct number are seen in kidneys and in liver.
Hilmi Demirkıran, Celaleddin Soyalp, Mehmet Kilic, Cevdet Yardimci, Nureddin Yuzkat, Arzu Esen Tekeli, Muhammed Bilal Çeğin   +6 more
doaj   +1 more source

Polycystic Disease of the Liver, Pancreas and Kidneys [PDF]

, 1939
Manville W. Norton
openalex   +1 more source

Vascular Dysfunction, Oxidative Stress, and Inflammation in Autosomal Dominant Polycystic Kidney Disease.

American Society of Nephrology. Clinical Journal, 2018
BACKGROUND AND OBJECTIVES Both increased arterial stiffness and vascular endothelial dysfunction are evident in patients with autosomal dominant polycystic kidney disease, even early in the course of the disease when kidney function in preserved ...
Kristen L. Nowak, Wei Wang, Heather Farmer-Bailey, Berenice Y. Gitomer, Mikaela Malaczewski, J. Klawitter, A. Jovanovich, M. Chonchol   +7 more
semanticscholar   +1 more source

Estimating the association and timing of occurrence between obesity and related comorbidity outcomes in a real‐world setting: A cohort study in the United States

Clinical Obesity, EarlyView.
Estimating the Association and Timing of Occurrence between Obesity and Related Comorbidity Outcomes in a Real‐World Setting: A Cohort Study in the United States. An observational, retrospective cohort study of adults with available body mass index (BMI) data during the period 2010–2019 in a large United States claims‐linked electronic health records ...
Firas Dabbous, Jigish Bhavsar, Jayashri Desai, Anthony Fabricatore, Bríain Ó. Hartaigh, Wojciech Michalak, Sariya Udayachalerm, Cynthia Saiontz‐Martinez, Zhenxiang Zhao, Fatima Cody Stanford   +9 more
wiley   +1 more source