Results 161 to 170 of about 462,629 (365)
Autosomal dominant polycystic kidney disease is a genetic disorder which results in the development of multiple cysts in the kidneys and other parenchymal organs. The two genes in which mutations are known to cause autosomal dominant polycystic kidney
Izabela Cwojdzińska-Jankowska+1 more
doaj
Clinical aspects of polycystic disease of the kidneys. [PDF]
H. David Mitcheson+2 more
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Abstract Aims To identify predictors of diabetic ketoacidosis (DKA) in patients with an insulin‐deficient phenotype initiating sodium‐glucose cotransporter 2 inhibitor (SGLT2i) therapy. Materials and Methods This retrospective cohort study analysed data from 31 900 patients with diabetes aged 18–70 identified as having an insulin‐deficient phenotype ...
Anat Tsur+4 more
wiley +1 more source
Adult type of polycystic disease of kidneys and liver presenting in childhood [PDF]
B. G. Ockenden
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The pathogenesis of polycystic kidney disease.
Polycystic kidney disease (PKD) is a genetic or acquired disorder characterized by progressive distention of multiple tubular segments and manifested by fluid accumulation, growth of non-neoplastic epithelial cells and remodeling of the extracellular matrix resulting ultimately in some degree of renal functional impairment, with the potential for ...
Carone, F.A., Bacallao, R., Kanwar, Y.S.
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Malignant hypertension (MHT) is a rare, severe condition with high morbidity and mortality. Using data from 385 patients in the West Birmingham MHT Registry, this study evaluated nine machine learning (ML) algorithms to predict a composite outcome of all‐cause mortality/dialysis over a median 11‐year follow‐up.
Antonios A. Argyris+7 more
wiley +1 more source
The average weight of a kidney is approximately 135 gm, measuring on average 10 × 6 × 4 cm. In hereditary conditions, autosomal dominant and autosomal recessive polycystic kidney disease, the shape, size, and the weight can be significantly abnormal ...
Anup Hazra+3 more
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Targeting the vasopressin type-2 receptor for renal cell carcinoma therapy. [PDF]
Arginine vasopressin (AVP) and its type-2 receptor (V2R) play an essential role in the regulation of salt and water homeostasis by the kidneys. V2R activation also stimulates proliferation of renal cell carcinoma (RCC) cell lines in vitro.
Calvet, James P+10 more
core
Emerging roles for integrated stress response signaling in homeostasis
Integrated stress response (ISR), an evolutionarily conserved eukaryotic stress‐adaptive program in eukaryotes, has also been implicated in homeostatic functions. This review covers a broad body of literature and presents several homeostatic functions of ISR in the absence of stress: (a) developmental processes (morphogenesis, differentiation, aging), (
Shyama Nandakumar+2 more
wiley +1 more source
Case Report: Autosomal dominant polycystic kidney disease and Wilms’ tumor in infancy and childhood
BackgroundAutosomal dominant polycystic kidney disease (ADPKD) is rare but one of the most common inherited kidney diseases. Normal kidney function is maintained until adulthood in most patients.
Doviltyte Zina+9 more
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