Results 61 to 70 of about 451,989 (311)
Role of Image Acquisition and Patient Phenotype Variations in Automatic Segmentation Model Generalization [PDF]
Purpose: This study evaluated the out-of-domain performance and generalization capabilities of automated medical image segmentation models, with a particular focus on adaptation to new image acquisitions and disease type. Materials: Datasets from both non-contrast and contrast-enhanced abdominal CT scans of healthy patients and those with polycystic ...
arxiv
Adenoma of the Ampulla of Vater: A Genetic Condition? [PDF]
The etiology of adenoma of the ampulla of Vater is not well understood. Previous authors reported the association of this neoplasm with polycystic kidney disease of two fraternal sisters. They concluded that these two conditions were somehow related.
Carey, Larry C., Serafini, Francesco M.
core +3 more sources
BackgroundAutosomal dominant polycystic kidney disease (ADPKD) is rare but one of the most common inherited kidney diseases. Normal kidney function is maintained until adulthood in most patients.
Doviltyte Zina+9 more
doaj +1 more source
Effect of ovariectomy on the progression of chronic kidney disease-mineral bone disorder (CKD-MBD) in female Cy/+ rats [PDF]
Male Cy/+ rats have shown a relatively consistent pattern of progressive kidney disease development that displays multiple key features of late stage chronic kidney disease-mineral bone disorder (CKD-MBD), specifically the development of cortical bone ...
Allen, Matthew R.+7 more
core +1 more source
BACKGROUND Previous clinical studies of autosomal dominant polycystic kidney disease (ADPKD) reported that loss of kidney function usually follows a steep and relentless course.
G. Brosnahan+15 more
semanticscholar +1 more source
A systems-biology approach to understanding the ciliopathy disorders. [PDF]
'Ciliopathies' are an emerging class of genetic multisystemic human disorders that are caused by a multitude of largely unrelated genes that affect ciliary structure/function.
Gleeson, Joseph G, Lee, Ji Eun
core +1 more source
Polycystic Kidney Disease Drug Development: A Conference Report
Autosomal dominant polycystic kidney disease (ADPKD) is part of a spectrum of inherited diseases that also includes autosomal recessive polycystic kidney disease, autosomal dominant polycystic liver disease, and an expanding group of recessively ...
Max C. Liebau+4 more
doaj
Polycystic kidney disease is one of the most common inheritable renal diseases, characterized by the formation of multiple fluid-filled renal cysts. This disease is a progressive and unfortunately incurable condition.
Tohru Kimura
doaj +1 more source
Autosomal Dominant Polycystic Kidney Disease: Core Curriculum 2016.
Autosomal dominant polycystic kidney disease (ADPKD) is the most common monogenic kidney disease. It is characterized by relentless development of kidney cysts, hypertension, and eventually end-stage renal disease (ESRD).
F. Chebib, V. Torres
semanticscholar +1 more source
Emerging targeted strategies for the treatment of autosomal dominant polycystic kidney disease. [PDF]
Autosomal dominant polycystic kidney disease (ADPKD) is a widespread genetic disease that leads to renal failure in the majority of patients. The very first pharmacological treatment, tolvaptan, received Food and Drug Administration approval in 2018 ...
Bourgeois, Bryan C+4 more
core +1 more source