Results 81 to 90 of about 2,624,306 (259)
Liver Organoids: From Disease Modelling to Regenerative Medicine
Cell Proliferation, EarlyView.Liver organoids provide a versatile platform for disease modelling and drug discovery, leveraging stem cells and engineering techniques. They bridge research and clinical applications, offering significant potential for advancing precision medicine and regenerative therapies for liver diseases.
Tiepeng Wang +5 more
wiley +1 more source
Molecular and cellular pathogenesis of autosomal recessive polycystic kidney disease
Brazilian Journal of Medical and Biological Research, 2006 Autosomal recessive polycystic kidney disease (ARPKD) is an inherited disease characterized by a malformation complex which includes cystically dilated tubules in the kidneys and ductal plate malformation in the liver.
L.F. Menezes, L.F. Onuchic
doaj
Diabetes, Obesity and Metabolism, EarlyView.ABSTRACT Aims This study quantified the real‐world healthcare costs and utilisation associated with diagnosed metabolic dysfunction‐associated steatotic liver disease (MASLD) among adults with Type 2 diabetes (T2D). Methods We conducted a retrospective cohort study using IQVIA PharMetrics Plus Closed Health Plan data from January 2016 to June 2025 ...
Tien Hoang Tran +3 more
wiley +1 more source
Impaired carotid viscoelastic properties in women with polycystic ovaries [PDF]
, 2002 Background-The purpose of this study was to assess the elastic properties of the carotid arteries in women with polycystic ovarian syndrome, asymptomatic women with polycystic ovaries.
Seifalian, AM, Lakhani, K, Hardiman, P
core
AUTOSOMAL – DOMINANT POLYCYSTIC KIDNEY DISEASE – A GLEAM OF HOPE? [PDF]
, 2014 The review contains information about modern conception ofautosomal–dominant polycystic kidney disease, its genetics, epidemiology, pathogenesis, course, clinical presentation and the results of recent clinical ...
V.V. Doretskyi, Y.V. Doretskyi
core +1 more source
Hemodialysis International, EarlyView.ABSTRACT Background Optimizing volume status is central to hemodialysis care and may influence patient‐reported outcome measures as recovery time. We evaluated the implementation of a structured decision aid (Recova) integrating symptom assessment with bioimpedance spectroscopy in routine hemodialysis practice.
Maaike Nielen +7 more
wiley +1 more source
Polycystic Diseases in Visceral Organs
Obstetrics and Gynecology International, 2011 Primary cilia are nonmotile, microtubule-based, antenna-like organelles projecting from the apical surface of most mammalian cells. Elegant studies have established the importance of ciliary structure and function in signal transduction and the sensory ...
Shakila Abdul-Majeed, Surya M. Nauli
doaj +1 more source
Phenotypic variability in siblings with autosomal recessive polycystic kidney disease
, 2022 © 2022 International Society of NephrologyIntroduction: Autosomal recessive polycystic kidney disease (ARPKD) is a rare monogenic disorder characterized by early onset fibrocystic hepatorenal changes.
GÖKCE, İBRAHİM
core +1 more source
Hemodialysis International, EarlyView.ABSTRACT Background Uremic pruritus (UP) remains a common and distressing complication in patients with end‐stage renal disease (ESRD) receiving maintenance hemodialysis. The burden is particularly pronounced in low‐ and middle‐income countries where twice‐weekly hemodialysis is frequently practiced because of resource limitations. Gabapentin is widely
Bilal Mohsin +9 more
wiley +1 more source
CRISPR-Cas9 system in autosomal dominant polycystic kidney disease: a comprehensive review [PDF]
Childhood Kidney DiseasesGenetic kidney diseases are caused by mutations in specific genes that significantly affect kidney development and function. Although the underlying pathogenic genes of many kidney diseases have been identified, an understanding of their mechanisms and ...
Seungyeon Kang +4 more
doaj +1 more source