Results 91 to 100 of about 34,123 (218)

The pathogenesis of polycystic kidney disease.

open access: yesHistology and histopathology, 1995
Polycystic kidney disease (PKD) is a genetic or acquired disorder characterized by progressive distention of multiple tubular segments and manifested by fluid accumulation, growth of non-neoplastic epithelial cells and remodeling of the extracellular matrix resulting ultimately in some degree of renal functional impairment, with the potential for ...
Carone, F.A., Bacallao, R., Kanwar, Y.S.
openaire   +2 more sources

Therapeutic Potential of Chickpea‐Derived Bioactives: A Review With Perspective of Different In Vitro, Animal, and Human Studies

open access: yesLegume Science, Volume 8, Issue 3, September 2026.
ABSTRACT Chickpea (Cicer arietinum L.) is an important dietary legume worldwide and provides micronutrients and phytochemicals, including phenolics, flavonoids, carotenoids, bioactive peptides, dietary fiber, and resistant starch. This narrative review summarizes evidence from in vitro, animal, and human studies on the potential health relevance of ...
Rohama Shahid   +4 more
wiley   +1 more source

Molecular Mechanisms of Food Bioactive Constituents in the Management of Obesity and Hypertension: A Critical Review

open access: yesPhytochemicals in Food and Medicine, Volume 1, Issue 3, September 2026.
Obesity and hypertension co‐exist and share molecular mechanisms in terms of dietary therapy, modulated by food bioactive constituents. ABSTRACT Obesity and hypertension are among the most pressing global public health challenges. They frequently co‐exist, with obesity‐related hypertension accounting for an estimated 75% of the hypertension burden ...
Samuel Oluwasegun Maccarthy   +3 more
wiley   +1 more source

A Woman With “Polycystic Kidney Disease” [PDF]

open access: yesKidney International Reports, 2020
Tu, Yan   +6 more
openaire   +2 more sources

Course of Portal Hypertension and Its Prognostic Impact After Liver Transplantation

open access: yesUnited European Gastroenterology Journal, Volume 14, Issue 7, September 2026.
ABSTRACT Background While portal hypertension (PH) typically resolves after liver transplantation (LT), persistence of PH may affect post‐transplant outcomes. We assessed the evolution of PH after LT and its impact on adverse outcomes. Methods We recorded clinical, laboratory, and imaging parameters of LT recipients between 2016 and 2022 in Vienna and ...
Nina Dominik   +20 more
wiley   +1 more source

Obesity in Classic Congenital Adrenal Hyperplasia: Mechanisms, Complications and Management

open access: yesClinical Endocrinology, Volume 105, Issue 3, Page 271-284, September 2026.
ABSTRACT Classic congenital adrenal hyperplasia (CCAH) is an autosomal recessive genetic disorder primarily caused by 21‐hydroxylase deficiency. Although the survival rate of patients has significantly improved with glucocorticoid replacement therapy, long‐term use of supraphysiological doses and multiple factors inherent to the disease itself have led
Jialin Mu   +5 more
wiley   +1 more source

Abnormal Glycaemic Fluctuations Associated With Early Microvascular Changes in the Retina and Choroid of Nondiabetic Adults

open access: yesDiabetes, Obesity and Metabolism, Volume 28, Issue 9, Page 7864-7874, September 2026.
ABSTRACT Aims To evaluate the association between continuous glucose monitoring (CGM)‐derived glycaemic variability indicators and early microvascular changes of the retina and choroid in nondiabetic individuals. Materials and Methods Community‐based individuals at high risk for type 2 diabetes (T2DM) underwent detailed assessments including oral ...
Yan Jiang   +15 more
wiley   +1 more source

Dose–Response Association Between Systemic and Dermatologic Glucocorticoid Use and Type 2 Diabetes Mellitus: A Nationwide Case–Control Study

open access: yesDiabetes, Obesity and Metabolism, Volume 28, Issue 9, Page 8094-8102, September 2026.
ABSTRACT Aims To investigate the association and dose–response between systemic and topical glucocorticoids and odds of Type 2 diabetes mellitus. Materials and Methods We conducted a nationwide case–control study using Danish registry data from 2013 to 2021. People aged 40 years or older with incident type 2 diabetes mellitus (n = 149 113) were matched
David Vadsholt   +6 more
wiley   +1 more source

Assessment of glycemic susceptibility across multiple urological and reproductive disorders

open access: yesDiabetology & Metabolic Syndrome
Objective To test the glycemic susceptibility in three urological cancers and eight urological/reproductive diseases using the Mendelian randomization (MR) method.
Xiongfeng Zeng   +3 more
doaj   +1 more source

Home - About - Disclaimer - Privacy