Results 101 to 110 of about 34,123 (218)
Diagnostic and therapeutic potential of interleukin-37 in kidney diseases: A mini-review
Interleukin-37 (IL-37) is a newly discovered anti-inflammatory cytokine from the IL-1 family that plays a key role in regulating both innate and adaptive immune responses.
Nadiia Demikhova +4 more
doaj +1 more source
ABSTRACT Aims Treatment options for metabolic dysfunction‐associated steatotic liver disease (MASLD) are limited. While glucagon‐like peptide‐1 receptor agonists (GLP‐1 RA) and sodium‐glucose cotransporter‐2 (SGLT‐2) inhibitors improve cardiovascular outcomes, comparative effectiveness on liver‐related outcomes remains unclear.
Gregor A. Maier +4 more
wiley +1 more source
Prevalence of Obesity and Related Conditions and GLP‐1 Use in Medicare Fee‐for‐Service Beneficiaries
ABSTRACT Aims This study estimated the number and percentage of Medicare fee‐for‐service (FFS) beneficiaries who use GLP‐1 RAs, are currently eligible or could become eligible if ongoing‐trial indications receive approval and coverage. Materials and Methods This retrospective cohort study used Medicare enrolment and claims data, representing 100% of ...
Sonia Kim +3 more
wiley +1 more source
Role of MCP-1 as an inflammatory biomarker in nephropathy
The Monocyte chemoattractant protein-1 (MCP-1), also referred to as chemokine ligand 2 (CCL2), belongs to the extensive chemokine family and serves as a crucial mediator of innate immunity and tissue inflammation.
Yanlong Liu +8 more
doaj +1 more source
ABSTRACT Aims This study aimed to analyse incident glucose lowering drug (GLD) utilisation in Australia between the period 2014 and 2024. Materials and Methods Australian Pharmaceutical Benefits Scheme (PBS) data (10% PBS dataset) were analysed to assess the proportions of incident monotherapy, dual therapy and triple therapy and the proportion of ...
Peter S. Hamblin +5 more
wiley +1 more source
Polycythemia in Nephrotic Syndrome
The association of polycythemia with kidney diseases such as adult polycystic kidney disease, kidney tumors, and renal artery stenosis is well known. However, polycythemia associated with nephrotic syndrome (NS) is rarely seen and documented.
Anagha Auradkar +2 more
doaj +1 more source
ABSTRACT Background Regular exercise is recommended for patients undergoing haemodialysis; however, participation rates remain low in Japan. Perceived benefits and barriers are key cognitive determinants of exercise behaviour, yet no validated instrument exists to assess these perceptions among Japanese patients receiving haemodialysis.
Ryota Kumakura +5 more
wiley +1 more source
The Role of Fat‐Free Mass in Weight‐Related Complications: A Rapid Review and Meta‐Analysis
ABSTRACT Background This review synthesized evidence on the association between fat‐free mass (FFM) metrics and weight‐related metabolic complications in adults with overweight or obesity. Methods A systematic search of Medline, Embase, Web of Science, and Google Scholar (inception to October 2024) identified 32 observational studies involving 138,935 ...
Tadesse Asmamaw Dejenie +4 more
wiley +1 more source
A Quarter Century of EHD Protein Research: From Endosomal Recycling to Ciliopathies
Human EHD protein subcellular localization. ABSTRACT Eps15 homology domain‐containing proteins comprise a conserved family of membrane‐remodeling ATPases that regulate endocytic trafficking, membrane fission, receptor recycling, primary ciliogenesis and membrane dynamics across eukaryotes. Since the initial identification of EHD1 and its Caenorhabditis
Devin Frisby +3 more
wiley +1 more source
ABSTRACT Background Breast cancer is the most common malignancy in women, and its incidence is increasing worldwide. Type 2 diabetes mellitus (T2DM) is a significant comorbidity in patients with breast cancer that negatively affects prognosis. Metformin, a first‐line antidiabetic drug, has been suggested to possess antineoplastic properties. This study
Ensiyeh Bahadoran +4 more
wiley +1 more source

