Results 101 to 110 of about 33,975 (227)

Non-ciliary Roles of IFT Proteins in Cell Division and Polycystic Kidney Diseases. [PDF]

Front Cell Dev Biol, 2020
Vitre B, Guesdon A, Delaval B.
europepmc   +1 more source

A Quarter Century of EHD Protein Research: From Endosomal Recycling to Ciliopathies

Traffic, Volume 27, Issue 3, September 2026.
Human EHD protein subcellular localization. ABSTRACT Eps15 homology domain‐containing proteins comprise a conserved family of membrane‐remodeling ATPases that regulate endocytic trafficking, membrane fission, receptor recycling, primary ciliogenesis and membrane dynamics across eukaryotes. Since the initial identification of EHD1 and its Caenorhabditis
Devin Frisby, Gunjan Misri, Naava Naslavsky, Steve Caplan   +3 more
wiley   +1 more source

Cardiorenal Outcomes of Dapagliflozin vs. Empagliflozin in Advanced Chronic Kidney Disease and Diabetes

Clinical Pharmacology &Therapeutics, Volume 120, Issue 1, Page 168-177, July 2026.
Target trial emulation of a multi‐institutional electronic health record network showed comparable cardiorenal effectiveness and safety of dapagliflozin versus empagliflozin in adults with type 2 diabetes and advanced‐stage chronic kidney disease.
Shih‐Hsuan Lin, Jia‐Jin Chen, Ching‐Chung Hsiao, Yu‐Wei Fang, Meng‐Ting Chen, Ming‐Hsien Tsai, Huang‐Yu Yang   +6 more
wiley   +1 more source

The Effects of Glucagon‐Like Peptide‐1 Receptor Agonists and Sodium‐Glucose Co‐Transporter‐2 Inhibitors on Lean Body Mass in Humans: A Systematic Review and Meta‐Analysis of Randomised Controlled Trials

Diabetes/Metabolism Research and Reviews, Volume 42, Issue 5, July 2026.
ABSTRACT Aims The use of pharmacotherapies with weight loss properties for the management of obesity and chronic disease are now routinely prescribed. We investigated the evidence from randomised‐controlled trials for the effects on lean body mass of glucagon‐like peptide‐1 receptor agonists (GLP‐1RA) and sodium‐glucose co‐transporter‐2 inhibitors ...
Rishi Jobanputra, Jack A. Sargeant, Tatiana Plekhanova, Emily James, Abdullah Almaqhawi, David R. Webb, Melanie J. Davies, Thomas Yates   +7 more
wiley   +1 more source

Assessment of glycemic susceptibility across multiple urological and reproductive disorders

Diabetology & Metabolic Syndrome
Objective To test the glycemic susceptibility in three urological cancers and eight urological/reproductive diseases using the Mendelian randomization (MR) method.
Xiongfeng Zeng, Zhen Li, Lede Lin, Xin Wei   +3 more
doaj   +1 more source

Dietary Phytochemical Index and Its Relationship With Diminished Ovarian Reserve: Evidence From a Case–Control Study

Endocrinology, Diabetes &Metabolism, Volume 9, Issue 4, July 2026.
A higher dietary phytochemical index was associated with lower odds of diminished ovarian reserve, highlighting the potential role of phytochemical‐rich diets in supporting ovarian function and reproductive health. ABSTRACT Introduction Diminished ovarian reserve (DOR) represents a significant contributor to female infertility and adverse reproductive ...
Mahdieh Khodarahmi, Gholamreza Askari, Mahdi Vajdi, Amin Mokari‐Yamchi, Hatav Ghasemi‐Tehrani, Maryam Kalatehjari, Abed Ghavami   +6 more
wiley   +1 more source

Diagnostic and therapeutic potential of interleukin-37 in kidney diseases: A mini-review

Український Журнал Нефрології та Діалізу
Interleukin-37 (IL-37) is a newly discovered anti-inflammatory cytokine from the IL-1 family that plays a key role in regulating both innate and adaptive immune responses.
Nadiia Demikhova, Larysa Kuts, Svitlana Bokova, Olga Vlasenko, Eda Merisalu   +4 more
doaj   +1 more source

A first‐trimester mechanistic framework integrating three Physiopathologic biomarker domains for pre‐eclampsia classification

International Journal of Gynecology &Obstetrics, Volume 174, Issue 1, Page 182-191, July 2026.
Abstract Objective To develop and internally validate a mechanistic, three‐domain framework for early classification and prediction of pre‐eclampsia (PE) using first‐trimester angiogenic, uteroplacental, and maternal vascular biomarkers. Methods In a prospective cohort of 1925 singleton pregnancies screened at 11 to 13.6 weeks, placental growth factor (
Johnatan Torres‐Torres, Salvador Espino‐y‐Sosa, Raigam Jafet Martinez‐Portilla, Elsa Romelia Moreno‐Verduzco, Irma Eloisa Monroy‐Muñoz, Juan Mario Solis‐Paredes, Javier Perez Duran, Hector Borboa‐Olivares, Lourdes Rojas‐Zepeda   +8 more
wiley   +1 more source

Low‐frequency electroacupuncture attenuates insulin resistance in a rat model of diet‐induced maternal obesity

Pregnancy, Volume 2, Issue 4, July 2026.
Abstract Introduction Maternal obesity is highly prevalent worldwide, conferring elevated risks of maternal/fetal complications and adult‐onset disease in offspring. Obesity and pregnancy are both states of insulin resistance. Percutaneous electrical stimulation of skeletal muscle, better known as electroacupuncture (EA), mitigates insulin resistance ...
David J. Carr, Elizabeth Kelley, Morgan Sekhon, Megan Kawasaki, Keara McElroy‐Yaggy, R. Chris Skinner, Paul D. Taylor, Anna L. David, Elisabet Stener‐Victorin, Thomas L. Jetton   +9 more
wiley   +1 more source

Role of MCP-1 as an inflammatory biomarker in nephropathy

Frontiers in Immunology
The Monocyte chemoattractant protein-1 (MCP-1), also referred to as chemokine ligand 2 (CCL2), belongs to the extensive chemokine family and serves as a crucial mediator of innate immunity and tissue inflammation.
Yanlong Liu, Ke Xu, Yuhua Xiang, Boyan Ma, Hailong Li, Yuan Li, Yue Shi, Shuju Li, Yan Bai   +8 more
doaj   +1 more source