Results 71 to 80 of about 24,424 (206)

Endocrine and androgenic response to altitude training in professional cyclists

The Journal of Physiology, EarlyView.
Abstract figure legend Steroidal and endocrine variables are altered during altitude training. Abstract This study investigated endocrine and steroidal blood markers in 31 male elite cyclists monitored over 7 weeks, including a 3 week altitude training camp either at 2050 m (n = 19) or 3000 m (n = 12).
Raphael Faiss, Bastien Krumm, Claes Cubel, Magnus Bak Klaris, Lasse Vestli Baekken, Yvette Dehnes, Jenna Goodrum, Geoff Miller, James Spragg, Martin Faulhaber, Francesco Botrè, Carsten Lundby   +11 more
wiley   +1 more source

Augmenting erythropoiesis using recombinant human erythropoietin at sea level blunts the high altitude induced increase in erythropoiesis

The Journal of Physiology, EarlyView.
Abstract figure legend Pharmacologically augmenting erythropoiesis with rEPO at sea level blunts the high altitude induced erythropoiesis. Abstract Erythropoiesis increases with high altitude (HA) acclimatization. Recombinant human erythropoietin (rEPO) induces erythropoiesis.
Roy M. Salgado, Thomas A. Mayer, Gabrielle E. W. Giersch, Billie K. Alba, David E. Barney Jr, Aaron R. Caldwell, Nisha Charkoudian, Brandon M. Roberts, Afton D. Seeley, K. Riley Connor, Andrew M. Greenfield, Adam J. Luippold, Mark L. Plamper, Jermaine A. Ward, Shauna M. Ward, Benjamin J. Ryan   +15 more
wiley   +1 more source

Method Comparison of Dried Blood Spot and Plasma Apolipoprotein B Measurement on a Semi‐Automated Analyser: Toward Accessible Lipid Profiling in Resource‐Limited Settings

Analytical Science Advances, Volume 7, Issue 1, June 2026.
ABSTRACT Apolipoprotein B (ApoB) is a key marker of atherogenic lipoprotein burden, but conventional plasma‐based testing requires venous sampling and centralized laboratory infrastructure. Dried blood spot (DBS) sampling offers a minimally invasive alternative suitable for decentralized settings.
Bronwyn Pitampersad, Savathree Madurai, Bhavani Manivannan, Kayla Pillay, Sharana Mahomed   +4 more
wiley   +1 more source

Polycythemia at Moderate Altitude: Rethinking Screening for Polycythemia Vera

Journal of Applied Hematology
BACKGROUND: Polycythemia is a clinical condition characterized by increased red blood cell mass (RCM). With the aim to increase the sensitivity of capturing patients with polycythemia vera (PV), the hemoglobin (Hb) and hematocrit (Hct) thresholds were ...
Husain Y. Alkhaldy, Ali M. Assiri
doaj   +1 more source

A Murine Bispecific Antibody Efficiently Redirects T Cells Against Calr Mutated Stem Cells In Vivo

American Journal of Hematology, Volume 101, Issue 4, Page 697-709, April 2026.
ABSTRACT Calreticulin (CALR) mutations are prevalent in 20%–30% of patients with BCR::ABL1‐negative myeloproliferative neoplasms (MPN). Mutant calreticulin (mutCALR), presented by the thrombopoietin receptor (MPL, also known as TPOR or CD110) on the surface of the disease‐initiating MPN progenitors, represents an ideal target for curative ...
Shengen Xiong, Tamara Wais, Cecilia Varga, Christina Schueller, Sarada Achyutuni, Robert Kralovics   +5 more
wiley   +1 more source

Polycythemia in Nephrotic Syndrome

Indian Journal of Kidney Diseases
The association of polycythemia with kidney diseases such as adult polycystic kidney disease, kidney tumors, and renal artery stenosis is well known. However, polycythemia associated with nephrotic syndrome (NS) is rarely seen and documented.
Anagha Auradkar, Sandhya Suresh, Ramprasad Elumalai   +2 more
doaj   +1 more source

Pathogenesis and Therapeutics for Chronic Pruritus of Unknown Origin: A Systematic Review

International Journal of Dermatology, Volume 65, Issue 4, Page 706-723, April 2026.
ABSTRACT Chronic pruritus of unknown origin (CPUO) is a distressing condition characterized by persistent itch lasting over 6 weeks without an identifiable cause. The underlying mechanisms remain poorly understood, complicating diagnosis and treatment.
Yagiz Matthew Akiska, Isha Gandhi, Robert Adler, Deena Fayyad, Perya Bhagchandani, Shabnam Afzal, Waleed Adawi, Shivani Patel, Shawn G. Kwatra   +8 more
wiley   +1 more source

Structural and Functional Validation of Pseudomonas Savastanoi Ethylene Forming Enzymes Reveals Flexibility in 2‐Oxoglutarate Binding Mode and Conformation

ChemBioChem, Volume 27, Issue 5, 13 March 2026.
Studies with naturally occuring variants of the Pseudomonas savastanoi ethylene‐forming enzyme (PsEFE) inform on the effect of residues on turnover and product ratio. Crystallographic studies imply a potential for metal ion sensing. Pseudomonas savastanoi pv.
Yihong Sun, Siddhant Dhingra, Mark D. Allen, Ethan S. Z. Cheng, Zhihong Zhang, Christopher J. Schofield, Lennart Brewitz   +6 more
wiley   +1 more source

What's Your Diagnosis? A Case of Extreme Thrombocytosis in a Dog

Veterinary Clinical Pathology, EarlyView.
Stephanie F. Anderson, King Long Hannah Lee, Megan Dietz, Sarah Guess, Laura White, Mara S. Varvil   +5 more
wiley   +1 more source

Is altitude‐induced polycythaemia an unintended evolutionary mistake?

Experimental Physiology, EarlyView.
Peter D. Wagner, Tatum S. Simonson
wiley   +1 more source