Results 91 to 100 of about 287,802 (318)

Inflammation and thrombosis in essential thrombocythemia and polycythemia vera: different role of C-reactive protein and pentraxin 3

open access: yesHaematologica, 2011
We tested the hypothesis that levels of pentraxin high sensitivity C-reactive protein and pentraxin 3 might be correlated with cardiovascular complications in patients with essential thrombocythemia and polycythemia vera.
Tiziano Barbui   +15 more
doaj   +1 more source

Two-hit model of leukemogenesis in the evolution of polycythemia vera to acute myeloid leukemia [PDF]

open access: yes, 2009
Polycythemia vera (PV) is a chronic myeloproliferative disorder that can evolve to marrow fibrosis or acute leukemia (AML). Cytogenetic alterations can be detected in around 25% of patients at diagnosis and in up to 50% of those with progression.
Chauffaille, Maria de Lourdes Lopes Ferrari   +2 more
core   +1 more source

Pipobroman therapy of polycythemia vera [PDF]

open access: yesBlood, 1982
Abstract Between 1971 and 1981, 74 patients with polycythemia vera were treated with pipobroman using a high-dose induction, low-dose maintenance regimen. Complete remission was achieved in 51 of 54 previously untreated patients (94.4%) and in 17 of 20 patients (85%) previously treated wih radioactive phosphorus (32 p) and busulfan.
Duhamel G   +4 more
openaire   +4 more sources

Expert Perspective: Hematologic Malignancies and Vasculitis

open access: yes
Arthritis &Rheumatology, EarlyView.
Michelle L. Robinette, Hetty E. Carraway
wiley   +1 more source

Re-evaluation of hematocrit as a determinant of thrombotic risk in erythrocytosis

open access: yesHaematologica, 2019
Here we critically evaluate the role of elevated hematocrit as the principal determinant of thrombotic risk in polycythemia and erythrocytosis, defined by an expansion of red cell mass.
Victor R. Gordeuk   +2 more
doaj   +1 more source

Hypercalcemia in a Patient with Polycythemia Vera [PDF]

open access: yesChonnam Medical Journal, 2012
A 59-year-old female with diabetes mellitus presented with hypercalcemia and polycythemia. Her serum calcium and intact parathyroid hormone (iPTH) levels were increased, and Tc-99m sesta-MIBI scanning showed hot uptake in the lower portion of the left thyroid lobe. After parathyroidectomy, her calcium, iPTH, and polycythemia were normalized.
Min Jee Kim   +8 more
openaire   +3 more sources

Clinical outcomes under hydroxyurea treatment in polycythemia vera: a systematic review and meta-analysis

open access: yesHaematologica, 2019
Hydroxyurea is the standard treatment in high-risk patients with polycythemia vera. However, estimates of its effect in terms of clinical outcomes (thrombosis, bleeding, hematologic transformations and mortality) are lacking. We performed a meta-analysis
A. Ferrari   +7 more
semanticscholar   +1 more source

Final Results From a Large, Non‐Interventional, Phase 4 Study of Ruxolitinib for the Treatment of Myelofibrosis in Clinical Routine

open access: yesEuropean Journal of Haematology, Volume 115, Issue 4, Page 380-390, October 2025.
ABSTRACT JAKoMo was a long‐term, multicenter, non‐interventional study observing the efficacy, safety, and quality of life (QOL) effects of ruxolitinib (RUX), managed per clinical routine at investigator discretion, for treatment of 943 patients with myelofibrosis (MF) in 122 German centers.
Steffen Koschmieder   +15 more
wiley   +1 more source

Gambaran Gen Jak2 Pada Penderita Polisitemia Vera Di Laboratorium Center for Biomedical Research (Cebior) Semarang [PDF]

open access: yes, 2015
Background: Polycythemia vera ( PV ) is one of the myeloproliferative Malignancies. The Jak2V617F mutation is found in approximately 96 percent of people with PV. JAK2 gene mutation results in the production of an activated JAK2 protein, which appears to
Faradz, S. M. (Sultana)   +2 more
core   +3 more sources

Transient Spinal Cord Ischemia as Presenting Manifestation of Polycythemia Vera

open access: yesCase Reports in Neurology, 2011
Spinal arterial vascularization is supplied by a large anastomotic net, making spinal ischemic events far less common than ischemic cerebral strokes. Polycythemia vera, due to blood hyperviscosity and activated platelet aggregation, is associated with a ...
Sónia Costa   +3 more
doaj   +1 more source

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