Results 91 to 100 of about 303,632 (262)

Hyperviscosity‐Related Ischemic Stroke in an Adolescent With Unrepaired Tetralogy of Fallot: A Case Report From a Resource‐Limited Setting

Clinical Case Reports, Volume 14, Issue 4, April 2026.
ABSTRACT Tetralogy of Fallot (TOF) is the most common cyanotic congenital heart disease. Chronic hypoxemia in uncorrected TOF causes compensatory erythrocytosis and hyperviscosity, predisposing to cerebrovascular complications. Stroke in this context is rare but clinically significant, especially in resource‐limited settings where access to imaging and
Ayenew A. Wolie, Chernet T. Mengistie, Biruk T. Mengistie, Elleni D. Mulatu, Rahel N. Teferi, Birhanu T. Andeta, Gedefaw T. Minwagaw   +6 more
wiley   +1 more source

Myelopathy due to Spinal Extramedullary Hematopoiesis in a Patient with Polycythemia Vera

Case Reports in Orthopedics, 2017
Extramedullary hematopoiesis (EMH) occasionally occurs in patients exhibiting hematological disorders with decreased hematopoietic efficacy. EMH is rarely observed in the spinal epidural space and patients are usually asymptomatic.
Shuhei Ito, Nobuyuki Fujita, Naobumi Hosogane, Narihito Nagoshi, Mitsuru Yagi, Akio Iwanami, Kota Watanabe, Takashi Tsuji, Masaya Nakamura, Morio Matsumoto, Ken Ishii   +10 more
doaj   +1 more source

Evaluating the effect of anti–cancer nano drugs dosage and reduced leukemia and polycythemia vera levels on trend of the human blood and bone marrow cancers under synchrotron radiation

Trends in Research, 2019
Leukemia is a cancer of the blood and bone marrow; there are many types of leukemia, depending on which type of white blood cell is involved. Treatment varies with the type and stage of disease.
A. Heidari, R. Gobato
semanticscholar   +1 more source

Role of Chitinase 3–like‐1 in Myelofibrosis via Fibroblast‐Produced Extracellular Matrix Enhancement

Journal of Cellular Physiology, Volume 241, Issue 4, April 2026.
Our results indicate the involvement of CHI3L1 in the fibrocyte–fibroblast interaction and exacerbate BM fibrosis by promoting extracellular matrix formation. CHI3L1 is a missing link between fibrocytes and myofibroblasts and is a new potential therapeutic target for MF treatment.
Shoichiro Kato, Toshikuni Kawamura, Takaaki Maekawa, Hiraku Ogata, Noriaki Tachi, Yukiko Osawa, Shinichi Kobayashi   +6 more
wiley   +1 more source

Inflammation and thrombosis in essential thrombocythemia and polycythemia vera: different role of C-reactive protein and pentraxin 3

Haematologica, 2011
We tested the hypothesis that levels of pentraxin high sensitivity C-reactive protein and pentraxin 3 might be correlated with cardiovascular complications in patients with essential thrombocythemia and polycythemia vera.
Tiziano Barbui, Alessandra Carobbio, Guido Finazzi, Alessandro M. Vannucchi, Giovanni Barosi, Elisabetta Antonioli, Paola Guglielmelli, Alessandro Pancrazzi, Silvia Salmoiraghi, Pio Zilio, Cosimo Ottomano, Roberto Marchioli, Ivan Cuccovillo, Barbara Bottazzi, Alberto Mantovani, Alessandro Rambaldi   +15 more
doaj   +1 more source

Pathogenesis and Therapeutics for Chronic Pruritus of Unknown Origin: A Systematic Review

International Journal of Dermatology, Volume 65, Issue 4, Page 706-723, April 2026.
ABSTRACT Chronic pruritus of unknown origin (CPUO) is a distressing condition characterized by persistent itch lasting over 6 weeks without an identifiable cause. The underlying mechanisms remain poorly understood, complicating diagnosis and treatment.
Yagiz Matthew Akiska, Isha Gandhi, Robert Adler, Deena Fayyad, Perya Bhagchandani, Shabnam Afzal, Waleed Adawi, Shivani Patel, Shawn G. Kwatra   +8 more
wiley   +1 more source

Transient Spinal Cord Ischemia as Presenting Manifestation of Polycythemia Vera

Case Reports in Neurology, 2011
Spinal arterial vascularization is supplied by a large anastomotic net, making spinal ischemic events far less common than ischemic cerebral strokes. Polycythemia vera, due to blood hyperviscosity and activated platelet aggregation, is associated with a ...
Sónia Costa, Joana Marques, Anabela Barradas, Ana Valverde   +3 more
doaj   +1 more source

Nosocomial Co-Transmission of Avian Influenza A(H7N9) and A(H1N1)pdm09 Viruses between 2 Patients with Hematologic Disorders [PDF]

, 2016
A nosocomial cluster induced by co-infections with avian influenza A(H7N9) and A(H1N1)pdm09 (pH1N1) viruses occurred in 2 patients at a hospital in Zhejiang Province, China, in January 2014.
Bi, Y, Chai, C, Chen, E, Chen, H, Chen, HX, Gao, GF, Jiang, C, Jin, T, Liu, G, Liu, J, Liu, S, Mao, H, Peiris, JSM, Shao, H, Tan, S, Tang, Y, Wang, Q, Yu, H, Yu, Z, Zhu, C, Zhu, G, Zou, Z   +21 more
core   +1 more source

Targeting BCL‐xL in Myeloid Malignancies: From Inhibitors to PROTAC

Journal of Cellular and Molecular Medicine, Volume 30, Issue 7, April 2026.
ABSTRACT Restoring apoptosis in malignant cells represents a central goal of anticancer therapy. Tumour cells often escape cell death by overexpressing anti‐apoptotic members of the BCL‐2 protein family, particularly BCL‐2, BCL‐xL, and MCL1. These proteins inhibit the intrinsic mitochondrial apoptotic pathway through intricate interactions with pro ...
Daniela Cilloni, Alessandro Ferrando, Francesco Frassoni   +2 more
wiley   +1 more source

Re-evaluation of hematocrit as a determinant of thrombotic risk in erythrocytosis

Haematologica, 2019
Here we critically evaluate the role of elevated hematocrit as the principal determinant of thrombotic risk in polycythemia and erythrocytosis, defined by an expansion of red cell mass.
Victor R. Gordeuk, Nigel S. Key, Josef T. Prchal   +2 more
doaj   +1 more source