Results 91 to 100 of about 287,802 (318)
We tested the hypothesis that levels of pentraxin high sensitivity C-reactive protein and pentraxin 3 might be correlated with cardiovascular complications in patients with essential thrombocythemia and polycythemia vera.
Tiziano Barbui+15 more
doaj +1 more source
Two-hit model of leukemogenesis in the evolution of polycythemia vera to acute myeloid leukemia [PDF]
Polycythemia vera (PV) is a chronic myeloproliferative disorder that can evolve to marrow fibrosis or acute leukemia (AML). Cytogenetic alterations can be detected in around 25% of patients at diagnosis and in up to 50% of those with progression.
Chauffaille, Maria de Lourdes Lopes Ferrari+2 more
core +1 more source
Pipobroman therapy of polycythemia vera [PDF]
Abstract Between 1971 and 1981, 74 patients with polycythemia vera were treated with pipobroman using a high-dose induction, low-dose maintenance regimen. Complete remission was achieved in 51 of 54 previously untreated patients (94.4%) and in 17 of 20 patients (85%) previously treated wih radioactive phosphorus (32 p) and busulfan.
Duhamel G+4 more
openaire +4 more sources
Expert Perspective: Hematologic Malignancies and Vasculitis
Arthritis &Rheumatology, EarlyView.
Michelle L. Robinette, Hetty E. Carraway
wiley +1 more source
Re-evaluation of hematocrit as a determinant of thrombotic risk in erythrocytosis
Here we critically evaluate the role of elevated hematocrit as the principal determinant of thrombotic risk in polycythemia and erythrocytosis, defined by an expansion of red cell mass.
Victor R. Gordeuk+2 more
doaj +1 more source
Hypercalcemia in a Patient with Polycythemia Vera [PDF]
A 59-year-old female with diabetes mellitus presented with hypercalcemia and polycythemia. Her serum calcium and intact parathyroid hormone (iPTH) levels were increased, and Tc-99m sesta-MIBI scanning showed hot uptake in the lower portion of the left thyroid lobe. After parathyroidectomy, her calcium, iPTH, and polycythemia were normalized.
Min Jee Kim+8 more
openaire +3 more sources
Hydroxyurea is the standard treatment in high-risk patients with polycythemia vera. However, estimates of its effect in terms of clinical outcomes (thrombosis, bleeding, hematologic transformations and mortality) are lacking. We performed a meta-analysis
A. Ferrari+7 more
semanticscholar +1 more source
ABSTRACT JAKoMo was a long‐term, multicenter, non‐interventional study observing the efficacy, safety, and quality of life (QOL) effects of ruxolitinib (RUX), managed per clinical routine at investigator discretion, for treatment of 943 patients with myelofibrosis (MF) in 122 German centers.
Steffen Koschmieder+15 more
wiley +1 more source
Gambaran Gen Jak2 Pada Penderita Polisitemia Vera Di Laboratorium Center for Biomedical Research (Cebior) Semarang [PDF]
Background: Polycythemia vera ( PV ) is one of the myeloproliferative Malignancies. The Jak2V617F mutation is found in approximately 96 percent of people with PV. JAK2 gene mutation results in the production of an activated JAK2 protein, which appears to
Faradz, S. M. (Sultana)+2 more
core +3 more sources
Transient Spinal Cord Ischemia as Presenting Manifestation of Polycythemia Vera
Spinal arterial vascularization is supplied by a large anastomotic net, making spinal ischemic events far less common than ischemic cerebral strokes. Polycythemia vera, due to blood hyperviscosity and activated platelet aggregation, is associated with a ...
Sónia Costa+3 more
doaj +1 more source