Results 101 to 110 of about 282,663 (297)
Dysregulated iron metabolism in polycythemia vera: etiology and consequences
Leukemia, 2018 Polycythemia vera (PV) is a chronic myeloproliferative neoplasm. Virtually all PV patients are iron deficient at presentation and/or during the course of their disease.
Y. Ginzburg +5 more
semanticscholar +1 more source
JEADV Clinical Practice, Volume 4, Issue 2, Page 407-415, June 2025.ABSTRACT Background Pruritus is a symptom frequently associated with systemic diseases, particularly hematological disorders. Objectives The aim of this study was to evaluate the association of pruritus with morbidity in myeloproliferative neoplasms (MPN).
J. Saucereau +4 more
wiley +1 more source
The SMAC mimetic LCL-161 selectively targets JAK2V617F mutant cells. [PDF]
, 2020 Background:Evasion from programmed cell death is a hallmark of cancer and can be achieved in cancer cells by overexpression of inhibitor of apoptosis proteins (IAPs).
Craver, Brianna M +6 more
core
Studies on the iron metabolism of erythroblasts in various blood diseases [PDF]
, 1960 The serum iron contents and the number of sideroblasts from various patients and the radioactivity of erythroblasts from the same patients incubated with Fe55 have been observed.
Kimura, Ikuro +2 more
core +1 more source
Ruxolitinib versus standard therapy for the treatment of polycythemia vera.
New England Journal of Medicine, 2015 BACKGROUND Ruxolitinib, a Janus kinase (JAK) 1 and 2 inhibitor, was shown to have a clinical benefit in patients with polycythemia vera in a phase 2 study.
A. Vannucchi +16 more
semanticscholar +1 more source
JAKing up hematopoietic proliferation [PDF]
, 2005 Mutations that deregulate proliferation and survival pathways have emerged as a common molecular theme in the pathogenesis of myeloproliferative disorders (MPDs).
Shannon, Kevin, Van Etten, Richard A.
core +1 more source
Seminars in Immunopathology, 2018 The first clinical trials of the safety and efficacy of interferon-alpha2 (IFN-alpha2) were performed about 30 years ago. Since then, several single-arm studies have convincingly demonstrated that IFN-alpha2 is a highly potent anti-cancer agent in ...
H. Hasselbalch, M. Holmström
semanticscholar +1 more source
Annals of Saudi Medicine, 2016 Polycythemia vera is a Philadelphia chromosome-negative myeloproliferative neoplasm. Chronic lymphocytic leukemia is a monoclonal expansion of a CD5+ CD19+ B lymphocytes.
Serdal Korkmaz +4 more
doaj +1 more source
Policitemia Vera en el perro : a propósito de un caso clínico [PDF]
, 1996 Se describe un caso de policitemia vera en perro. Se discute el diagnóstico diferencial del proceso, pronóstico y tramiento.A c1inical case of primary polycythemia in a dog is described.
Aceña Fabián, M. Carmen +4 more
core
Differential NOD/SCID mouse engraftment of peripheral blood CD34 + cells and JAK2V617F clones from patients with myeloproliferative neoplasms [PDF]
, 2010 We evaluated the NOD/SCID engraftment of CD34 + cells from polycythemia vera (PV) and secondary polycythemia patients (SP) and the JAK2V617F clone before and after transplantation. Peripheral blood CD34 + cells were transplanted intra-femorally.
Cheung, AMS +4 more
core +1 more source